公开(公告)号：KR101193607B1

公开(公告)日：2012-11-09

申请号：KR1020110015268

申请日：2011-02-21

Applicant: 한국과학기술원

Inventor： 박현규 ,  원병연

IPC: G01N27/22 ,  G01N33/48 ,  G06F3/044

CPC classification number: G06F3/044 ,  G01N27/3276

Abstract: There is provided a method of detecting biomolecules using a capacitive touch screen receiving a touch with a conductor as an input signal to perform an output on a display screen, and more particularly to a method of detecting target biomolecules by applying biomolecules having electrical conductivity to a touch panel and detecting a change in capacitance of a surface of a touch panel generated according to the concentration of the biomolecules. A method of detecting biomolecule according to the present invention uses a capacitive touch screen capable of being cheaply manufactured on a large scale, such that the method may have advantages such as cheap cost and a short analysis time and simply detect biomolecules in a personal terminal such as a smart phone, a tablet PC, and the like, on which a capacitive touch screen is mounted, as compared to the existing method requiring an expensive exclusive analysis apparatus based on absorbance or fluorescence having a large volume, a skilled experimental technique such as electrophoresis, or a long analysis time to thereby be performed only in an experimental room equipped with specialists and equipment.

公开(公告)号：KR1020120095754A

公开(公告)日：2012-08-29

申请号：KR1020110015268

申请日：2011-02-21

Applicant: 한국과학기술원

Inventor： 박현규 ,  원병연

IPC: G01N27/22 ,  G01N33/48 ,  G06F3/044

CPC classification number: G06F3/044 ,  G01N27/3276

Abstract: PURPOSE: A method for detecting target organic molecule using a touch screen of a capacitance mode is provided to simply detect an organic molecule with a private terminal in which a touch screen of a capacitance mode is loaded. CONSTITUTION: A method for detecting target organic molecule using a touch screen of a capacitance mode is as follows. A standard specimen or one or more organic molecules desired to detect are applied to a touch panel of a touch screen of a capacitance mode. A sub panel coated with a transparent electrode in which a conducting wire is connected or a sub panel which both sides are coated with the transparent electrode is laminated on a touch panel so that a side in which the transparent electrode is coated contact to the touch panel. A conductor contacts with the conducting wire connected to the transparent electrode or the electronic transparent in a surface opposite to the surface contacting to the touch panel, thereby changing the capacitance of a surface of the touch panel. One position of contact signals is measured by using a touch controller, thereby detecting the concentration of the organic molecule.

Abstract translation: 目的：提供使用电容模式的触摸屏来检测目标有机分子的方法，以简单地检测具有电容模式的触摸屏的专用终端的有机分子。 构成：使用电容模式的触摸屏检测目标有机分子的方法如下。 将标准样品或希望检测的一种或多种有机分子应用于电容模式的触摸屏的触摸面板。 涂覆有导电线的透明电极的子面板或两侧都涂覆有透明电极的子面板层叠在触摸面板上，使得其中涂覆有透明电极的一面与触摸面板接触 。 导体与连接到透明电极的导线或电子透明体在与触摸面接触的表面相对的表面上接触，从而改变触摸面板的表面电容。 通过使用触摸控制器测量接触信号的一个位置，从而检测有机分子的浓度。

公开(公告)号：KR1020110033575A

公开(公告)日：2011-03-31

申请号：KR1020090091123

申请日：2009-09-25

Applicant: 한국과학기술원

Inventor： 박현규 ,  이진우 ,  김문일 ,  심종민 ,  이태화

IPC: C12N11/14 ,  G01N33/552

Abstract: PURPOSE: A porous silica composite and a method for preparing the same are provided to sensitively diagnose pathogens, small molecular material, proteins, and DNA. CONSTITUTION: A porous silica composite comprises: magnetic nanoparticles with peroxidase activity; and an enzyme which provides a reactive substrate catalyzed by peroxidase or an enzyme using a reactant catalyzed by peroxidase. The substrate catalyzed by hydrogen peroxide is hydrogen peroxide. The reactant catalyzed by peroxidase is water(H_2O) or oxygen(O_2). The porous silica is MSU, SBA, MCM, or KIT. A method for preparing the porous silica composite comprises: a step of precipitating the magnetic particles inside a pore of the silica; and a step of fixing the enzyme into the pore.

Abstract translation: 目的：提供多孔二氧化硅复合物及其制备方法，以敏感地诊断病原体，小分子材料，蛋白质和DNA。 构成：多孔二氧化硅复合材料包括：具有过氧化物酶活性的磁性纳米颗粒; 以及提供由过氧化物酶或酶催化的反应性底物的酶，其使用由过氧化物酶催化的反应物。 由过氧化氢催化的底物是过氧化氢。 由过氧化物酶催化的反应物是水（H_2O）或氧（O_2）。 多孔二氧化硅是MSU，SBA，MCM或KIT。 一种多孔二氧化硅复合体的制造方法，其特征在于，包括使所述二氧化硅的细孔内的磁性粒子析出的工序; 以及将酶固定到孔中的步骤。

公开(公告)号：KR1020080114396A

公开(公告)日：2008-12-31

申请号：KR1020070063912

申请日：2007-06-27

Applicant: 한국과학기술원

Inventor： 박현규 ,  정철희 ,  문효영 ,  이태화

IPC: C12Q1/68 ,  B82Y5/00

CPC classification number: C12Q1/6834 ,  B82Y5/00 ,  C12Q1/6837

Abstract: A method for fixating a biomass on a substrate using gold nanoparticle is provided to increase an immobilization capacity of the biomass compared with an existing method by uniting gold nanoparticles with many biomasses by a three dimensional structure and be uniformly immobilized and steadily formed compared with the existing covalent bond due to bond by the adsorption with the gold nanoparticles and the substrate. A method for fixating a biomass on a substrate using gold nanoparticles includes steps of: (a) manufacturing gold nanoparticles-biomass composite by mixing the gold nanoparticles and the biomass; and (b) fixing the substrate of the gold nanoparticles-biomass composite through adsorption of the substrate and the gold nanoparticles by spotting the composite on the substrate.

Abstract translation: 提供了一种使用金纳米颗粒固定在基材上的生物质的方法，以增加生物量与现有方法的固定能力，通过三维结构将金纳米颗粒与许多生物质结合在一起，并与现有的方法相比被均匀地固定和稳定地形成 由于通过与金纳米颗粒和基底的吸附而结合而引起的共价键。 使用金纳米颗粒在基材上固定生物质的方法包括以下步骤：（a）通过混合金纳米颗粒和生物质来制造金纳米颗粒 - 生物质复合材料; 和（b）通过在基材上点样复合材料来吸附底物和金纳米颗粒来固定金纳米颗粒 - 生物质复合材料的基材。

公开(公告)号：KR100787489B1

公开(公告)日：2007-12-24

申请号：KR1020040066675

申请日：2004-08-24

Applicant: 한국과학기술원

Inventor： 박현규 ,  이태화

IPC: G01N21/31 ,  B82Y35/00 ,  B82Y30/00

Abstract: 본 발명은 은 나노입자에 결합된 키랄성 화합물을 원평광 이색성 분광법을 이용하여 분석하는 방법에 관한 것으로, 더욱 상세하게는, 은 나노입자와 키랄성 물질이 티올기를 통해서 결합함으로써 근자외선 영역에서 새로운 원평광 이색성 분광 신호가 나타나고, 이러한 현상을 키랄성 화합물의 분석에 이용하는 방법에 관한 것이다.
본 발명에서 특징적으로 얻어지는 원평광 이색성 분광 시그널은 키랄성 물질의 유·무, 키랄성 물질 내에 함유되어 있는 티올기의 유·무 및 은 나노입자와 결합된 키랄성 물질의 작용기들 사이의 수소결합의 여부를 측정하는데 유용하다.
은 나노입자, 키랄성 물질, 원평광 이색성 분광법