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公开(公告)号:DK270489A
公开(公告)日:1989-12-05
申请号:DK270489
申请日:1989-06-02
Applicant: HOECHST AG
Inventor: BONIN WERNER , HABERMANN PAUL , TRIPIER DOMINIQUE , WOEHNER ELISABET
IPC: A61K38/55 , A61K35/56 , A61K38/00 , A61P7/02 , C07K1/14 , C07K1/16 , C07K14/00 , C07K14/435 , C07K14/44 , C07K14/81 , C07K15/08 , C07K3/28 , A61K37/02
Abstract: The invention relates to a new active substance-amblyommin-for anticoagulant therapy and to a process for the isolation thereof from hard ticks. The isolated protein having a thrombin-inhibitory action has a molecular weight of 20000 to 30000 dalton, an isoelectric point between 5.05 and 5.65 and the partial amino acid sequences Ile-Leu-Phe-Thr-Gln-Gly-Asn-X-Gly-Glu-Leu-Glu-Asn-X-Phe-Glu-, Lys-Ile-Leu-Phe-X-Gln-Gly- and Ala-Ser-Tyr-Ile-Val-X-Ser-Glu-Ser-Ile-Gln-Ile-Leu-X-Leu-Ser-Glu-Gly-Ile- in which each radical X can be identical or different and each represents a naturally occurring amino acid.
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公开(公告)号:ZA889014B
公开(公告)日:1989-08-30
申请号:ZA889014
申请日:1988-12-01
Applicant: HOECHST AG
Inventor: KOCH VOLKER , VOLKER KOCH , SCHNATTERER STEFAN , STEFAN SCHNATTERER , BONIN WERNER , WERNER BONIN , KERN MANFRED , MANFRED KERN , KNAUF WERNER , WERNER KNAUF , WALTERSDORFER ANNA , ANNA WALTERSDORFER
IPC: A01N43/88 , A01N47/30 , A01N47/34 , A01P7/02 , A01P7/04 , C07C317/24 , C07C317/42 , C07C323/22 , C07C323/27 , C07C323/44 , C07C335/26 , C07D273/04 , C07C , A01N , C07D
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公开(公告)号:ZA8809014B
公开(公告)日:1989-08-30
申请号:ZA8809014
申请日:1988-12-01
Applicant: HOECHST AG
Inventor: KOCH VOLKER , VOLKER KOCH , SCHNATTERER STEFAN , STEFAN SCHNATTERER , BONIN WERNER , WERNER BONIN , KERN MANFRED , MANFRED KERN , KNAUF WERNER , WERNER KNAUF , WALTERSDORFER ANNA , ANNA WALTERSDORFER
IPC: A01N43/88 , A01N47/30 , A01N47/34 , A01P7/02 , A01P7/04 , C07C317/42 , C07C323/27 , C07C323/44 , C07C335/26 , C07D273/04 , C07C , A01N , C07D
CPC classification number: C07C317/42 , A01N43/88 , A01N47/34 , C07C323/27 , C07C335/26 , C07D273/04
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公开(公告)号:AU2653688A
公开(公告)日:1989-06-08
申请号:AU2653688
申请日:1988-12-02
Applicant: HOECHST AG
Inventor: KOCH VOLKER , SCHNATTERER STEFAN , BONIN WERNER , KERN MANFRED , KNAUF WERNER , WALTERSDORFER ANNA
IPC: A01N43/88 , A01N47/30 , A01N47/34 , A01P7/02 , A01P7/04 , C07C317/24 , C07C317/42 , C07C323/22 , C07C323/27 , C07C323/44 , C07C335/26 , C07D273/04 , C07C149/437 , C07C147/12 , C07C147/14 , C07C157/12
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公开(公告)号:DK270489D0
公开(公告)日:1989-06-02
申请号:DK270489
申请日:1989-06-02
Applicant: HOECHST AG
Inventor: BONIN WERNER , HABERMANN PAUL , TRIPIER DOMINIQUE , WOEHNER ELISABET
IPC: A61K38/55 , A61K35/56 , A61K38/00 , A61P7/02 , C07K1/14 , C07K1/16 , C07K14/00 , C07K14/435 , C07K14/44 , C07K14/81 , C07K15/08 , C07K3/28 , A61K37/02
Abstract: The invention relates to a new active substance-amblyommin-for anticoagulant therapy and to a process for the isolation thereof from hard ticks. The isolated protein having a thrombin-inhibitory action has a molecular weight of 20000 to 30000 dalton, an isoelectric point between 5.05 and 5.65 and the partial amino acid sequences Ile-Leu-Phe-Thr-Gln-Gly-Asn-X-Gly-Glu-Leu-Glu-Asn-X-Phe-Glu-, Lys-Ile-Leu-Phe-X-Gln-Gly- and Ala-Ser-Tyr-Ile-Val-X-Ser-Glu-Ser-Ile-Gln-Ile-Leu-X-Leu-Ser-Glu-Gly-Ile- in which each radical X can be identical or different and each represents a naturally occurring amino acid.
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公开(公告)号:AU7364187A
公开(公告)日:1987-12-03
申请号:AU7364187
申请日:1987-05-29
Applicant: HOECHST AG
Inventor: GIENCKE WOLFGANG , MILDENBERGER HILMAR , HEUBACH GUNTHER , SACHSE BURKHARD , FUSS ANDREAS , WALTERSDORFER ANNA , KNAUF WERNER , KERN MANFRED , BONIN WERNER
IPC: A01N43/54 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/48 , C07D239/50 , C07D239/52
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公开(公告)号:ZA8702742B
公开(公告)日:1987-11-25
申请号:ZA8702742
申请日:1987-04-16
Applicant: HOECHST AG
Inventor: KOCH VOLKER , VOLKER KOCH , FUSS ANDREAS , ANDREAS FUSS , BONIN WERNER , WERNER BONIN , KNAUF WERNER , WERNER KNAUF , WALTERDORFER ANNA , ANNA WALTERDORFER
IPC: A01N43/88 , A01N47/34 , C07C67/00 , C07C275/24 , C07C275/44 , C07C275/54 , C07C325/00 , C07C335/26 , C07D273/04 , C07D319/12 , C07C
CPC classification number: C07C275/54 , A01N43/88 , A01N47/34 , C07C275/44 , C07C335/26 , C07D273/04 , C07D319/12
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公开(公告)号:HUT42291A
公开(公告)日:1987-07-28
申请号:HU117386
申请日:1986-03-20
Applicant: HOECHST AG
Inventor: KOCH VOLKER , BONIN WERNER , KNAUF WERNER , WALTERSDORFER ANNA
IPC: A01N47/34 , C07C275/44 , C07D207/32 , C07D207/325 , A01N47/40 , C07C127/19 , C07D207/30 , C07D213/60
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公开(公告)号:ZW4280A1
公开(公告)日:1980-09-10
申请号:ZW4280
申请日:1980-02-21
Applicant: HOECHST AG
Inventor: STAHLER GERHARD , AKHILESWAR SINHARAY , BONIN WERNER
Abstract: Compounds of the formula in which R1 is halogen, alkyl, alkoxy, alkylthio, CF3, NO2, CN2, phenoxy, halophenoxy, phenylthio or halophenylthio, R2 is CN or COOR3, R3 is alkyl, alkoxyalkyl or cycloalkyl and n is 0 to 3 are effective insecticides and acaricides and especially ectoparasiticides.
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公开(公告)号:AU7917275A
公开(公告)日:1976-09-23
申请号:AU7917275
申请日:1975-03-17
Applicant: HOECHST AG
Inventor: STAHLER GERHARD , EMMEL LUDWIG , BONIN WERNER
Abstract: Mono- and dithiophosphonic acid esters of the formula I in which R is optionally substituted alkyl, cycloalkyl, cycloalkenyl, or optionally substituted phenyl, R' is optionally substituted alkyl, alkenyl, or cycloalkyl, R'' and R''' which are identical or different, are hydrogen, halogen, methyl, methoxy, nitro or trifluoromethyl, and X is oxygen or sulfur, are useful insecticides and acaricides.
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