公开(公告)号：US2275173A

公开(公告)日：1942-03-03

申请号：US36761140

申请日：1940-11-28

Applicant: REMINGTON ARMS CO INC

Inventor： WILLI BRUN

IPC: C07C205/24

CPC classification number: C07C201/10 ,  C07B2200/13 ,  Y10S149/111 ,  C07C205/24

公开(公告)号：US2275171A

公开(公告)日：1942-03-03

申请号：US36760940

申请日：1940-11-28

Applicant: REMINGTON ARMS CO INC

Inventor： WILLI BRUN

IPC: C07C205/24

CPC classification number: C07C201/10 ,  C07B2200/13 ,  C07C205/24

公开(公告)号：US2137234A

公开(公告)日：1938-11-22

申请号：US67404933

申请日：1933-06-02

Applicant: REMINGTON ARMS CO INC

Inventor： WILLI BRUN

IPC: C07C205/24

CPC classification number: C07C201/10 ,  C07B2200/13 ,  C07C205/24

公开(公告)号：EP2298749B1

公开(公告)日：2014-12-24

申请号：EP10177806.6

申请日：1999-05-04

Applicant: BASF SE

Inventor： Rheinheimer, Joachim ,  von Deyn, Wolfgang ,  Gebhardt, Joachim ,  Rack, Michael ,  Lochtman, Rene ,  Götz, Norbert ,  Keil, Michael ,  Witschel, Matthias ,  Hagen, Helmut ,  Mißlitz, Ulf ,  Baumann, Ernst

IPC: C07D261/04 ,  C07D413/10 ,  C07C251/40 ,  C07C319/14

CPC classification number: C07C249/06 ,  C07C201/10 ,  C07C201/12 ,  C07C205/44 ,  C07C209/62 ,  C07C251/48 ,  C07C253/00 ,  C07C255/50 ,  C07C315/04 ,  C07C319/14 ,  C07D261/04 ,  C07D413/10 ,  C07C323/09 ,  C07C317/24 ,  C07C317/32 ,  C07C205/06 ,  C07C211/52

公开(公告)号：EP2196468A1

公开(公告)日：2010-06-16

申请号：EP10001846.4

申请日：2006-01-12

Applicant: Schering Corporation

Inventor： Wu, George G. ,  Sudhakar, Anantha ,  Wang, Tao ,  Xie, Ji ,  Chen, Frank Xing ,  Poirier, Marc ,  Huang, Mingsheng ,  Sabesen, Vijay ,  Kwok, Daw-long ,  Cui, Jian ,  Yang, Xiaojing ,  Thiruvengadam, Tiruvettipuram K. ,  Liao, Jing

IPC: C07F9/58

CPC classification number: C07D263/56 ,  C07C69/606 ,  C07C69/732 ,  C07C201/10 ,  C07C201/12 ,  C07C205/44 ,  C07C205/55 ,  C07C231/10 ,  C07C231/12 ,  C07C235/28 ,  C07C303/32 ,  C07C309/08 ,  C07C2601/16 ,  C07D277/64 ,  C07D307/92 ,  C07D333/56 ,  C07D405/06 ,  C07D413/06 ,  C07D417/06 ,  C07F7/1852 ,  C07F9/582 ,  Y02P20/55 ,  C07C233/28

Abstract: This application discloses a compound which is useful in the preparation of himbacine analogs as well as processes for its preparation:

wherein R 9 is selected from the group consisting of C 1 -C 10 alkyl, aryl, heteroaryl, and arylalkyl.

Abstract translation: 本申请公开了一种可用于制备烟肼类似物的化合物及其制备方法：其中R 9选自C 1 -C 10烷基，芳基，杂芳基和芳基烷基。

公开(公告)号：EP1077955B1

公开(公告)日：2007-06-27

申请号：EP99922160.9

申请日：1999-05-04

Applicant: BASF Aktiengesellschaft

Inventor： RHEINHEIMER, Joachim ,  VON DEYN, Wolfgang ,  GEBHARDT, Joachim ,  RACK, Michael ,  LOCHTMAN, Rene ,  GÖTZ, Norbert ,  KEIL, Michael ,  WITSCHEL, Matthias ,  HAGEN, Helmut ,  MISSLITZ, Ulf ,  BAUMANN, Ernst

IPC: C07D261/04 ,  C07D413/10 ,  C07C251/40 ,  C07C319/14

CPC classification number: C07C249/06 ,  C07C201/10 ,  C07C201/12 ,  C07C205/44 ,  C07C209/62 ,  C07C251/48 ,  C07C253/00 ,  C07C255/50 ,  C07C315/04 ,  C07C319/14 ,  C07D261/04 ,  C07D413/10 ,  C07C323/09 ,  C07C317/24 ,  C07C317/32 ,  C07C205/06 ,  C07C211/52

Abstract: The invention relates to a method for producing isoxazolene of the formula (I), where the substituents have the following meanings: R1 is hydrogen, C¿1?-C6 alkyl, R?2 is C¿1-C6 alkyl, R?3, R4, R5¿ are hydrogen, C¿1?-C6 alkyl or R?4 and R5¿ together form a linkage, R6 is a heterocyclic ring, and n is 0, 1 or 2. Said method comprises the production of an intermediate compound of the formula (VI) where R?1, R3, R4 and R5¿ have the meanings given above. This step is followed by halogenation, thiomethylation, oxidation and acylation to yield compounds of formula (I). The invention also relates to new intermediate products for producing compounds of formula (I) and new methods for producing the intermediate products.

公开(公告)号：EP1486479A1

公开(公告)日：2004-12-15

申请号：EP04253380.2

申请日：2004-06-07

Applicant: MITSUI CHEMICALS, INC.

Inventor： Funaki, Setsuko, c/o Mitsui Chemicals, Inc. ,  Taniguchi, Yoshiteru, c/o Mitsui Chemicals, Inc. ,  Nobori, Tadahito, c/o Mitsui Chemicals, Inc. ,  Yamamoto, Yoshihiro, c/o Mitsui Chemicals, Inc. ,  Hara, Isao, c/o Mitsui Chemicals, Inc. ,  Hayashi, Takaomi, c/o Mitsui Chemicals, Inc. ,  Mizutani, Kazumi, c/o Mitsui Chemicals, Inc. ,  Kiyono, Shinji, c/o Mitsui Chemicals, Inc.

IPC: C07B39/00 ,  C07B37/04 ,  C07B41/00 ,  C07B43/00 ,  C07D307/24 ,  C07D307/14 ,  C07C17/20 ,  C07C253/14 ,  C07C255/19 ,  C07C331/18 ,  C07D307/32 ,  C07C319/14 ,  C07C45/63 ,  C07C205/02 ,  C07C209/08 ,  C07F9/06

CPC classification number: C07D307/33 ,  C07B37/04 ,  C07B41/00 ,  C07B43/00 ,  C07C17/208 ,  C07C29/124 ,  C07C67/10 ,  C07C67/11 ,  C07C67/287 ,  C07C201/10 ,  C07C209/08 ,  C07C253/14 ,  C07C253/30 ,  C07C319/14 ,  C07C331/14 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2603/18 ,  C07D307/14 ,  C07D307/24 ,  C07C23/08 ,  C07C69/003 ,  C07C323/22 ,  C07C205/02 ,  C07C323/56 ,  C07C255/46 ,  C07C255/41 ,  C07C255/20 ,  C07C255/19 ,  C07C255/16 ,  C07C255/03 ,  C07C211/42 ,  C07C69/145 ,  C07C69/24 ,  C07C69/63 ,  C07C33/24

Abstract: The invention pertains to a method in which a halogen atom of an organic compound is replaced with a group derived from a nucleophilic agent, at high yield and high efficiency, by the following method which includes a step of reacting the nucleophilic agent with an organic material having a halogen atom bonded to a carbon atom having four σ bonds, more specifically: a method for producing an organic compound having Q, the method including a step of reacting a compound represented by general formula (2) with an organic starting material having at least one halogen atom bonded to a carbon atom having four σ bonds so as to replace the halogen atom in the organic starting material with Q:

        MQ a      (2)

(wherein M represents an alkali metal atom, an alkali earth metal atom, or a rare earth metal atom; Q represents a moiety of an inorganic acid or an active hydrogen compound derived by eliminating a proton, wherein Q is a halogen atom different from the halogen atom in the organic starting material having the halogen atom bonded to the carbon atom having the four σ bonds; and a represents an integer of 1 to 3) in the presence of a compound represented by general formula (1)
(wherein Z - represents an anion derived by eliminating a proton from an inorganic acid or an active hydrogen compound; R 2 is the same or different; R 2 each independently represent a C 1 -C 10 hydrocarbon group or two R 2 on the same nitrogen atom may be bonded with each other to form a ring with the nitrogen atom).

Abstract translation: 本发明涉及一种方法，其中有机化合物的卤素原子以高产率和高效率被来自亲核剂的基团替代，包括使亲核剂与有机材料反应的步骤 具有与具有四个σ键的碳原子键合的卤素原子，更具体地说：一种制备具有Q的有机化合物的方法，所述方法包括使通式（2）表示的化合物与具有式 与具有四个σ键的碳原子键合的至少一个卤素原子，以用Q：MQa（其中M表示碱金属原子，碱土金属原子或稀土金属原子）代替有机原料中的卤素原子 ; Q表示无机酸或通过除去质子衍生的活性氢化合物的部分，其中Q是与有机起始垫中的卤素原子不同的卤素原子 具有与具有四个σ键的碳原子键合的卤素原子的化合物; （1）表示的化合物（其中Z 1表示通过从无机酸或活性氢化合物中除去质子而得到的阴离子）的存在下，a表示1〜3的整数。 R2相同或不同; R2各自独立地表示C1-C10烃基，或者相同氮原子上的两个R2可以彼此键合以与氮原子形成环）。

公开(公告)号：EP0473464B1

公开(公告)日：1995-06-14

申请号：EP91401381.8

申请日：1991-05-29

Applicant: TAOKA CHEMICAL CO., LTD

Inventor： Kimura, Osamu ,  Horikawa, Yasuhiko ,  Yamashita, Masaya ,  Morino, Kazutaka ,  Koyama, Shinichi

IPC: C07C205/26 ,  C07C201/00

CPC classification number: C07C201/08 ,  C07C201/10 ,  C07C201/16 ,  C07C205/26

公开(公告)号：EP0540311A1

公开(公告)日：1993-05-05

申请号：EP92309875.0

申请日：1992-10-28

Applicant: EXXON RESEARCH AND ENGINEERING COMPANY

Inventor： Chiang, Long Yong ,  Upasani, Ravindra Balawant ,  Swirczewski, John Willard

IPC: C01B31/00 ,  C07C219/24 ,  C07C233/41 ,  C07C205/41 ,  C07C65/01 ,  C07C63/04 ,  B01J21/18 ,  C08G63/20 ,  C08G63/02 ,  C08G69/44

CPC classification number: B82Y30/00 ,  B82Y40/00 ,  C01B32/15 ,  C01B32/152 ,  C07C37/70 ,  C07C51/27 ,  C07C51/285 ,  C07C63/70 ,  C07C201/10 ,  C07C201/12 ,  C07C205/41 ,  C07C209/68 ,  C07C213/02 ,  C07C213/08 ,  C07C231/06 ,  C07C231/12 ,  C07C2603/97 ,  C07C2604/00 ,  C08G63/16 ,  Y10S977/734 ,  Y10S977/738 ,  Y10S977/753 ,  Y10S977/842 ,  Y10S977/848 ,  C07C205/18 ,  C07C215/44 ,  C07C219/24 ,  C07C211/42 ,  C07C233/06 ,  C07C237/02 ,  C07C39/12

Abstract: One embodiment of the present invention is directed to polysubstituted fullerene moieties having a plurality of substituents thereon, selected from hydroxy, oxide, nitro, amino, organocarboxy, amide, and mixtures thereof. Another embodiment is directed toward the preparation of the novel polysubstituted fullerenes which method comprises contacting fullerenes with an electrophilic reagent such as nitronium ion or an organic peracid. When the electrophilic agent is nitronium ion, the fullerene is further contacted with a nucleophilic reagent. The polysubstituted fullerenes are particularly useful as cross-linking agents in polymers and/or as core building blocks of star polymers.

Abstract translation: 本发明的一个实施方案涉及在其上具有多个取代基的多取代富勒烯部分，其选自羟基，氧化物，硝基，氨基，有机羧基，酰胺及其混合物。 另一个实施方案涉及新型多取代富勒烯的制备，该方法包括使富勒烯与亲电试剂如硝鎓离子或有机过酸接触。 当亲电子试剂是硝鎓离子时，富勒烯进一步与亲核试剂接触。 多取代的富勒烯特别可用作聚合物中的交联剂和/或作为星形聚合物的核心结构单元。

公开(公告)号：EP0151835A1

公开(公告)日：1985-08-21

申请号：EP84300713.9

申请日：1984-02-06

Applicant: UNIROYAL CHEMICAL COMPANY, Inc.

Inventor： Gay, Walter A. ,  Dietrich, Robert F.

IPC: C07C79/12 ,  C07C149/34

CPC classification number: C07C323/00 ,  C07C201/10 ,  C07C205/12

Abstract: Disclosed is a process for producing pentachloronitrobenzene (PCNB) by reacting hexachlorobenzene (HEX) with sodium hydrosulfide (NaSH) in the presence of sodium hydroxide (NaOH), sodium carbonate (Na 2 CO 3 ), or mixtures thereof to produce the sodium salt of pentachlorothiophenol (PCTP), followed by reacting it (or PTCP itself after acidifying) with nitric acid in the presence of sulfuric acid or oleum.