-
公开(公告)号：AU2010284240B2
公开(公告)日：2016-11-10
申请号：AU2010284240
申请日：2010-08-18
Applicant: ARRAY BIOPHARMA INC , VENTIRX PHARMACEUTICALS INC
Inventor： HOWBERT JAMES JEFFRY , DIETSCH GREGORY , HERSHBERG ROBERT , BURGESS LAURENCE E , LYSSIKATOS JOSEPH P , NEWHOUSE BRAD , YANG HONG WOON
IPC: C07D223/14 , A61K31/4025 , A61K31/454 , A61K31/55 , A61P31/00 , A61P35/00 , C07D401/14 , C07D403/10
Abstract: Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.
-
公开(公告)号：CY1112238T1
公开(公告)日：2015-12-09
申请号：CY111101002
申请日：2011-10-21
Applicant: ARRAY BIOPHARMA INC
Inventor： HANS JEREMY , WALLACE ELI M , ZHAO QIAN , LYSSIKATOS JOSEPH P , AICHER TOM , LAIRD ELLEN , ROBINSON JOHN , ALLEN SHELLEY
IPC: A61K31/4245 , C07D413/00 , C07D417/00
Abstract: Ηεφεύρεσηαυτήαφοράαναστολείςμιτωτικώνκινεσινών, ιδιαιτέρως KSP καιμεθόδουςπαρασκευήςαυτώντωναναστολέων. Ηεφεύρεσηεπίσηςπαρέχειφαρμακευτικέςσυνθέσειςπουπεριλαμβάνουντουςαναστολείςτηςεφεύρεσηςκαιμεθόδουςχρήσηςτωναναστολέωνκαιφαρμακευτικώνσυνθέσεωνστηθεραπείακαιπρόληψηδιαφόρωνδιαταραχών.
-
公开(公告)号：CA2606708C
公开(公告)日：2015-01-06
申请号：CA2606708
申请日：2006-05-01
Applicant: ARRAY BIOPHARMA INC
Inventor： HANS JEREMY , WALLACE ELI M , ZHAO QIAN , ALLEN SHELLEY , LAIRD ELLEN , LYSSIKATOS JOSEPH P , ROBINSON JOHN E , CORRETTE CHRISTOPHER P , DELISLE ROBERT KIRK , VOEGTLI WALTER CHARLES
IPC: C07D417/04 , A61K31/433 , A61K31/437 , C07D285/12 , C07D513/04
Abstract: This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.
-
公开(公告)号：IL212398A
公开(公告)日：2014-09-30
申请号：IL21239811
申请日：2011-04-14
Applicant: ASTRAZENECA AB , ARRAY BIOPHARMA INC , LYSSIKATOS JOSEPH P , BLAKE JIM , ALLISON MARLOW L , WALLACE ELI , SEO JEONGBEOB , YANG HOON WOON , STOREY RICHARD ANTHONY , BOOTH REBECCA JANE , PITTAM JOHN DAVID , LEONARD JOHN , FIELDING MARK RICHARD
Inventor： LYSSIKATOS JOSEPH P , BLAKE JIM , ALLISON MARLOW L , WALLACE ELI , SEO JEONGBEOB , YANG HOON WOON , STOREY RICHARD ANTHONY , BOOTH REBECCA JANE , PITTAM JOHN DAVID , LEONARD JOHN , FIELDING MARK RICHARD
IPC: A61K20060101 , A61P20060101 , C07D20060101
Abstract: This invention relates to a series of novel heterocyclic compounds that are useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. This invention also relates to a method of using such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
-
公开(公告)号：SI2334677T1
公开(公告)日：2013-12-31
申请号：SI200930782
申请日：2009-08-18
Applicant: ARRAY BIOPHARMA INC
Inventor： ALLEN SHELLEY , CELESTE LAURA L , DAVIS T GREGG , DELISLE ROBERT KIRK , GRESCHUK JULIE MARIE , GROSS STEFAN D , HICKEN ERIK JAMES , JACKSON LEILA J , LYSSIKATOS JOSEPH P , KALLAN NICHOLAS C , MARMSATER FREDRIK P , MUNSON MARK C , PHENEGER JED , RAST BRYSON , ROBINSON JOHN E , SCHLACHTER STEPHEN T , TOPALOV GEORGE T , WRIGHT A DALE , ZHAO QIAN
IPC: C07D471/00 , A61K31/00
-
Patent Agency Ranking
公开(公告)号：MY149960A
公开(公告)日：2013-11-15
申请号：MYPI20101331
申请日：2006-05-17
Applicant: ARRAY BIOPHARMA INC , ASTRAZENECA AB
Inventor： MARLOW ALLISON L , LEONARD JOHN , FIELDING MARK RICHARD , WALLACE ELI M , SEO JEONGBEOB , LYSSIKATOS JOSEPH P , YANG HONG WOON , BLAKE JAMES , STORY RICHARD ANTHONY , BOOTH REBECCA JANE , PITTAM JOHN DAVID
IPC: C07D237/24
Abstract: DISCLOSED ARE MEK INHIBITORS USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES, SUCH AS CANCER AND INFLAMMATION, IN MAMMALS, AND INFLAMMATORY CONDITIONS. ALSO DISCLOSED ARE METHODS OF USING SUCH COMPOUNDS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES IN MAMMALS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS.
-
公开(公告)号：MY149957A
公开(公告)日：2013-11-15
申请号：MYPI20062270
申请日：2006-05-17
Applicant: ARRAY BIOPHARMA INC , ASTRAZENECA AB
Inventor： MARLOW ALLISON L , LEONARD JOHN , FIELDING MARK RICHARD , WALLACE ELI M , SEO JEONGBEOB , LYSSIKATOS JOSEPH P , YANG HONG WOON , BLAKE JAMES , STOREY RICHARD ANTHONY , BOOTH REBECCA JANE , PITTAM JOHN DAVID
Abstract: DISCLOSED ARE MEK INHIBITORS USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES, SUCH AS CANCER AND INFLAMMATION, IN MAMMALS, AND INFLAMMATORY CONDITIONS. ALSO DISCLOSED ARE METHODS OF USING SUCH COMPOUNDS IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES IN MAMMALS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS.
-
公开(公告)号：PL2137184T3
公开(公告)日：2013-09-30
申请号：PL08744440
申请日：2008-03-27
Applicant: ARRAY BIOPHARMA INC
Inventor： ALLEN SHELLEY , GRESCHUK JULIE MARIE , KALLAN NICHOLAS C , MARMSÄTER FREDRIK P , MUNSON MARK C , RIZZI JAMES P , ROBINSON JOHN E , SCHLACHTER STEPHEN T , TOPALOV GEORGE T , ZHAO QIAN , LYSSIKATOS JOSEPH P
IPC: C07D471/04 , A61K31/33 , A61P35/00
-
公开(公告)号：PL2361905T3
公开(公告)日：2013-07-31
申请号：PL11003827
申请日：2006-05-17
Applicant: ARRAY BIOPHARMA INC , ASTRAZENECA AB
Inventor： STOREY RICHARD ANTHONY , BOOTH REBECCA JANE , PITTAM JOHN DAVID , MARLOW ALLISON L , WALLACE ELI , SEO JEONGBEOB , LYSSIKATOS JOSEPH P , YANG HONG WOON , BLAKE JIM , LEONARD JOHN , FIELDING MARK RICHARD
IPC: C07D237/24 , A61K31/501 , A61P35/00 , C07D213/80 , C07D213/82 , C07D213/85
-
公开(公告)号：DK2137184T3
公开(公告)日：2013-07-22
申请号：DK08744440
申请日：2008-03-27
Applicant: ARRAY BIOPHARMA INC
Inventor： ALLEN SHELLEY , GRESCHUK JULIE MARIE , KALLAN NICHOLAS C , MARMSAETER FREDRIK P , MUNSON MARK C , RIZZI JAMES P , ROBINSON JOHN E , SCHLACHTER STEPHEN T , TOPALOV GEORGE T , ZHAO QIAN , LYSSIKATOS JOSEPH P
IPC: C07D471/04 , A61K31/33 , A61P35/00
-
-
-
-
-
-
-
-
-
Search Results
330
records
(took 0.026 seconds)
