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公开(公告)号:BR0213773A
公开(公告)日:2004-10-13
申请号:BR0213773
申请日:2002-10-31
Applicant: BASF AG
Inventor: ZELDER OSKAR , POMPEJUS MARKUS , DER HARTWIG SCHR , GER BURKHARD KR , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
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公开(公告)号:DE10239082A1
公开(公告)日:2004-03-04
申请号:DE10239082
申请日:2002-08-26
Applicant: BASF AG
Inventor: KROEGER BURKHARD , ZELDER OSKAR , KLOPPROGGE CORINNA , SCHROEDER HARTWIG , HAEFNER STEFAN
Abstract: Method for fermentative production of at least one sulfur-containing fine chemical (I) by fermenting a (I)-producing coryneform bacterium (A); concentrating (I) in medium or cells, then isolating it. (A) expresses at least one heterologous nucleotide sequence (II) that encodes a protein (III) with O-acetylhomoserine-sulfhydrolase (metY) activity. An Independent claim is also included for preparation of a feed additive (B) that contains L-methionine by culturing/fermenting an L-Met producing microorganisms; removing water from the fermentation broth and optionally also up to 100% of the biomass, then drying the treated broth to recover (B) in powdered or granular form.
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公开(公告)号:DE10222858A1
公开(公告)日:2003-12-04
申请号:DE10222858
申请日:2002-05-23
Applicant: BASF AG
Inventor: SCHROEDER HARTWIG , KROEGER BURKHARD , ZELDER OSKAR , KLOPPROGGE CORINNA , HAEFNER STEFAN
Abstract: The invention relates to methods for the production of sulfur-containing fine chemicals, in particular L-methionine, by fermentation using bacteria in which a nucleotide sequence encoding an S-adenosylmethionine synthase (metK) gene is expressed.
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公开(公告)号:CA2484955A1
公开(公告)日:2003-11-27
申请号:CA2484955
申请日:2003-05-13
Applicant: BASF AG
Inventor: LEE HEUNG-SHICK , HAEFNER STEFAN , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , ZELDER OSKAR
Abstract: Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the ac eB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by insertin g, deleting or substituting up to 20% of the amino acids.
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115.
公开(公告)号:AU2003229691A8
公开(公告)日:2003-10-27
申请号:AU2003229691
申请日:2003-04-16
Applicant: BASF AG
Inventor: HAFNER STEFAN , KLOPPROGGE CORINNA , SCHRODER HARTWIG , ZELDER OSKAR , KROGER BURKHARD
IPC: A23K1/00 , A23K1/16 , C12N1/15 , C12N9/10 , C12N15/09 , C12P11/00 , C12P13/12 , C12R1/15 , C12N15/63
Abstract: The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metH) gene.
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公开(公告)号:AU2002365499A1
公开(公告)日:2003-06-10
申请号:AU2002365499
申请日:2002-10-31
Applicant: BASF AG
Inventor: POMPEJUS MARKUS , SCHRODER HARTWIG , KROGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR , ZELDER OSKAR
Abstract: Isolated nucleic acid (I) that encodes particular protein sequences (II) that have, at specific positions, an amino acid alteration. Independent claims are also included for: (1) Vector that contains at least one (I); (2) Host cell transfected with at least one vector of (1); and (3) Method for preparing fine chemicals by culturing cells of (2).
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公开(公告)号:DE10154245A1
公开(公告)日:2003-06-05
申请号:DE10154245
申请日:2001-11-05
Applicant: BASF AG
Inventor: ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
IPC: C07H21/04 , C07K14/34 , C12N1/21 , C12N9/12 , C12N9/16 , C12N9/90 , C12N15/31 , C12P13/08 , C12R1/15 , C12N15/11 , C12N15/77 , C12P13/04
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
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公开(公告)号:DE10155505A1
公开(公告)日:2003-05-22
申请号:DE10155505
申请日:2001-11-13
Applicant: BASF AG
Inventor: ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to an isolated nucleic acid molecule coding for a polypeptide comprising the amino acid sequence which is respectively referred to in table 1/column 2. Said nucleic acid molecule which is in the amino acid position indicated in table 1/column 4 codes for a different proteinogenous amino acid to the one which is indicated on the same line in table 1/column 5.
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公开(公告)号:AU2002346807A1
公开(公告)日:2003-05-19
申请号:AU2002346807
申请日:2002-10-31
Applicant: BASF AG
Inventor: SCHRODER HARTWIG , ZELDER OSKAR , KLOPPROGGE CORINNA , POMPEJUS MARKUS , KROGER BURKHARD , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
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公开(公告)号:DE10154292A1
公开(公告)日:2003-05-15
申请号:DE10154292
申请日:2001-11-05
Applicant: BASF AG
Inventor: ZELDER OSKAR , POMPEJUS MARKUS , SCHROEDER HARTWIG , KROEGER BURKHARD , KLOPPROGGE CORINNA , HABERHAUER GREGOR
Abstract: The invention relates to novel nucleic acid molecules, the use thereof in the construction of bio-engineering improved microorganisms and methods for the production of fine chemicals, especially amino acids with the aid of said bio-engineered improved microorganisms.
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