公开(公告)号：DK554776A

公开(公告)日：1977-06-14

申请号：DK554776

申请日：1976-12-10

Applicant: HOECHST AG

Inventor： BARTMANN W ,  KUNSTMANN R ,  LERCH U ,  SCHOELKENS B

IPC: C07D207/27 ,  A61K31/40 ,  A61K31/4015 ,  A61P43/00 ,  C07D207/26 ,  C07D

公开(公告)号：DK546176A

公开(公告)日：1977-06-06

申请号：DK546176

申请日：1976-12-03

Applicant: HOECHST AG

Inventor： BARTMANN W ,  BECK G ,  LERCH U ,  SEEGER K ,  TEUFEL H

IPC: A61K9/00 ,  A61K31/20 ,  A61P43/00 ,  C07C67/00 ,  C07C401/00 ,  C07C405/00 ,  C07D307/935 ,  C07F9/40 ,  C07C

公开(公告)号：SE7607331L

公开(公告)日：1976-12-28

申请号：SE7607331

申请日：1976-06-24

Applicant: HOECHST AG

Inventor： BARTMANN W ,  KUNSTMANN R ,  LERCH U ,  SCHOLKENS B

IPC: C07D207/27 ,  C07D207/26 ,  C07D498/04

公开(公告)号：DK287476A

公开(公告)日：1976-12-28

申请号：DK287476

申请日：1976-06-25

Applicant: HOECHST AG

Inventor： BARTMANN W ,  KUNSTMANN R ,  LERCH U ,  SCHOLKENS B

IPC: C07D207/27 ,  C07D207/26 ,  C07D498/04 ,  C07D

公开(公告)号：SE7606318L

公开(公告)日：1976-12-06

申请号：SE7606318

申请日：1976-06-03

Applicant: HOECHST AG

Inventor： BARTMANN W ,  BECK G ,  REUSCHLING D-B ,  SEEGER K ,  TEUFEL H

IPC: C07D333/16 ,  A61K31/557 ,  A61K31/5575 ,  A61P1/04 ,  A61P7/02 ,  A61P7/10 ,  A61P9/12 ,  A61P43/00 ,  C07C67/00 ,  C07C401/00 ,  C07C405/00 ,  C07D307/935 ,  C07D333/00 ,  C07D333/32 ,  C07D333/64 ,  C07D333/78 ,  C07D409/12 ,  C07D409/14 ,  C07F9/54 ,  C07C177/00

Abstract: The present invention relates to thienyl-prostaglandin derivatives and to a process for their manufacture. The compounds according to the invention have valuable pharmaceutical properties.

公开(公告)号：DK532376A

公开(公告)日：1976-11-25

申请号：DK532376

申请日：1976-11-25

Applicant: HOECHST AG

Inventor： TEUFEL H ,  BARTMANN W ,  GRANZER E ,  MUSIL J

IPC: C07C20060101 ,  C07C

公开(公告)号：ZA75957B

公开(公告)日：1976-01-28

申请号：ZA75957

申请日：1975-02-14

Applicant: HOECHST AG

Inventor： BECK G ,  LERCH U ,  BABEJ M ,  BARTMANN W

IPC: C07C405/00 ,  C07C ,  A61K ,  C07D

公开(公告)号：ZA747430B

公开(公告)日：1975-12-31

申请号：ZA747430

申请日：1974-11-20

Applicant: HOECHST AG

Inventor： BABEJ M ,  LERCH U ,  BARTMANN W ,  BECK G

IPC: C07D319/08 ,  C07C67/00 ,  C07C401/00 ,  C07C405/00 ,  C07D307/935 ,  C07D339/06 ,  C07D493/08 ,  C07C ,  C07D ,  A61K

Abstract: The present invention relates to novel not naturally occuring analogues of prostanoic acids of the formula (I) as well as a process for their preparation. The compounds of the invention have valuable pharmacological properties similar to those of the natural prostaglandins and therefore can be used as medicaments.

公开(公告)号：SE7507096L

公开(公告)日：1975-12-22

申请号：SE7507096

申请日：1975-06-19

Applicant: HOECHST AG

Inventor： TEUFEL H ,  BARTMANN W ,  BECK G ,  GRANZER E

IPC: A61K31/15 ,  A61K20060101 ,  C07C20060101 ,  C07C67/00 ,  C07C239/00 ,  C07C251/66 ,  C07C131/00

Abstract: Procedure for the preparation of substituted 0-acyl acrylaldoximes of the formula I **(See formula)** where X represents a chlorine or bromine atom, R represents an alcoholic, alkoxy or alkylamino group, an alkenyl, alkenoxy or alkenylamino group each having 1 to 12 carbon atoms, or an aryl, aryloxy, arylalkyl group, arylalkoxy, arylamino or arylalkoxylaminos possibly substituted with one or two alcohol groups, each with 1 to 6 carbon atoms-, and R1, R2, R3 and R4 are the same or different and mean in each case a hydrogen atom, a halogen atom or an alcoholic or alkoxy group in each case with 1 to 6 carbon atoms, characterized in that the 2,3-diaryl-3-halogen-acryloxy compounds of formula II are acylated **(See formula)** wherein X, R1, R2, R3 and R4 have the meanings given in the description of formula I, in the presence of aprotic solvents with the aid of acylating agents, to form 0-acyl-2,3-diaryl-3- halogen-acryl-oximes of formula I. (Machine-translation by Google Translate, not legally binding)

公开(公告)号：DK281175A

公开(公告)日：1975-12-22

申请号：DK281175

申请日：1975-06-20

Applicant: HOECHST AG

Inventor： TEUFEL H ,  BARTMANN W ,  BECK G ,  GRANZER E

IPC: A61K31/15 ,  A61K20060101 ,  C07C20060101 ,  C07C67/00 ,  C07C239/00 ,  C07C251/66 ,  C07C

Abstract: Procedure for the preparation of substituted 0-acyl acrylaldoximes of the formula I **(See formula)** where X represents a chlorine or bromine atom, R represents an alcoholic, alkoxy or alkylamino group, an alkenyl, alkenoxy or alkenylamino group each having 1 to 12 carbon atoms, or an aryl, aryloxy, arylalkyl group, arylalkoxy, arylamino or arylalkoxylaminos possibly substituted with one or two alcohol groups, each with 1 to 6 carbon atoms-, and R1, R2, R3 and R4 are the same or different and mean in each case a hydrogen atom, a halogen atom or an alcoholic or alkoxy group in each case with 1 to 6 carbon atoms, characterized in that the 2,3-diaryl-3-halogen-acryloxy compounds of formula II are acylated **(See formula)** wherein X, R1, R2, R3 and R4 have the meanings given in the description of formula I, in the presence of aprotic solvents with the aid of acylating agents, to form 0-acyl-2,3-diaryl-3- halogen-acryl-oximes of formula I. (Machine-translation by Google Translate, not legally binding)