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    NEAR INFRARED OPTICAL IMAGING SYSTEM FOR HEMODYNAMIC IMAGING, PULSE MONITORING, AND MAPPING SPATIO-TEMPORAL FEATURES
    111.
    发明公开
    NEAR INFRARED OPTICAL IMAGING SYSTEM FOR HEMODYNAMIC IMAGING, PULSE MONITORING, AND MAPPING SPATIO-TEMPORAL FEATURES 审中-公开
    光学NAHINFRAROTABBILDUNGSSYSTEM血流显像，脉冲计数器和图示的时空特征

    公开(公告)号：EP3091897A2

    公开(公告)日：2016-11-16

    申请号：EP15733318.8

    申请日：2015-01-06

    Applicant: The Florida International University Board of Trustees

    Inventor： GODAVARTY, Anuradha ,  JUNG, Youngjin

    IPC: A61B5/026 ,  A61B5/021 ,  A61B5/145

    CPC classification number: A61B5/02028 ,  A61B5/0059 ,  A61B5/02416 ,  A61B5/065 ,  A61B5/14551 ,  A61B5/7207 ,  A61B5/742 ,  A61B2560/0431 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/108 ,  G01J3/2823 ,  G01N2021/3155 ,  G01N2201/0221

    Abstract: The present application describes techniques to image biological tissue to determine biological information of an imaged tissue sample such as changes in hemoglobin concentrations, blood flow rate (pulse), and/or spatio-temporal features. Embodiments include illuminating the tissue sample with light in the near-infrared (NIR) spectrum, which is minimally absorbed but scattered through the tissue sample. By detecting the NIR light that is attenuated through, transmitted through, and/or reflected off the tissue to be imaged, the resulting NIR intensity signals may be further analyzed to provide this data. Embodiments include using multiple NIR light sources having varying wavelengths to obtain changes in the oxy- and deoxy-hemoglobin concentrations of the imaged tissue region. The tissue sample may be imaged over a time period, and the NIR images may be viewed statically or in real time after post-processing analyses have been performed.

    Abstract translation: 本申请描述的技术来图像生物组织成像的组织样本的速率的确定性矿生物信息：诸如血红蛋白浓度的变化，血流量（脉冲），和/或空间 - 时间特征。 实施例包括在近红外（NIR）光谱的光照射组织样品，所有这一切都被最低限度吸收而穿过组织样本散射。 通过检测通过衰减的NIR灯，反式mitted通过，和/或反射离开要被成像的组织，将得到的NIR强度信号可以被进一步分析，以提供该数据。 实施例包括使用具有不同波长的多个NIR光源，以获得在所成像的组织区域的氧和脱氧血红蛋白浓度的变化。 组织样品可以在一段时间内被成像，及后处理分析已经完成后的NIR图像可以被静态地或实时地观看。

    DEVICE FOR SETTING REGION OF INTEREST FOR ANALYSIS
    115.
    发明公开
    DEVICE FOR SETTING REGION OF INTEREST FOR ANALYSIS 审中-公开
    用于设置分析区域的设备

    公开(公告)号：EP2966433A1

    公开(公告)日：2016-01-13

    申请号：EP13876990.6

    申请日：2013-03-08

    Applicant: Shimadzu Corporation

    Inventor： NODA, Akira

    IPC: G01N21/35

    CPC classification number: G02B21/361 ,  G01J3/0248 ,  G01J3/0275 ,  G01J3/0289 ,  G01J3/108 ,  G01J3/28 ,  G01J3/453 ,  G01N21/35 ,  G01N2021/3595 ,  G02B21/365 ,  G06K9/0014 ,  G06K9/6202 ,  G06T7/0004 ,  G06T7/11 ,  G06T2207/10048 ,  G06T2207/10056 ,  G06T2207/20056 ,  G06T2207/30164

    Abstract: Provided is an analysis target region setting apparatus that can accurately set an analysis target region, based on an observation image of a sample obtained with an optical microscope and the like irrespective of texture on the sample surface when the analysis target region is set therein. The analysis target region setting apparatus according to the present invention divides the observation image into a plurality of sub-regions based on pixel information on each pixel constituting the observation image. Subsequently, consolidation information on each sub-region is calculated, and two adjacent sub-regions themselves are consolidated based on the consolidation information. According to this, it is possible to divide the observation image into sub-regions having similar pixel information with a disregard of noise attributed to the shape of a surface and the like. A user designates one sub-region from among the sub-regions finally obtained, as the analysis target region.

    Abstract translation: 本发明提供一种分析对象区域设定装置，该分析对象区域设定装置在分析对象区域被设定的情况下，能够基于通过光学显微镜等得到的样本的观察图像，与样本表面的纹理无关地高精度地设定分析对象区域。 根据本发明的分析目标区域设定设备基于构成观察图像的每个像素的像素信息将观察图像划分为多个子区域。 随后，计算每个子区域的合并信息，并根据合并信息合并两个相邻的子区域本身。 据此，可以将观察图像划分为具有相似像素信息的子区域，而不考虑归因于表面形状等的噪声。 用户从最终获得的子区域中指定一个子区域作为分析目标区域。

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