公开(公告)号：WO1997000640A1

公开(公告)日：1997-01-09

申请号：PCT/US1996010594

申请日：1996-06-19

Applicant: ADVANCED MEDICAL SYSTEMS, INC.

Inventor： ADVANCED MEDICAL SYSTEMS, INC. ,  HOJAIBAN, George ,  MALINOUSKAS, Donald

IPC: A61B05/00

CPC classification number: A61B5/14552 ,  A61B5/0261 ,  G11C7/106 ,  G11C7/1069

Abstract: Uterine activity is sensed (13) by passing (14, 16) light through the patient's abdominal wall and detecting (12) the light reflected from abdominal tissues. The intensity of the reflected light varies with the state of contraction of the patient's uterus. The use of light for monitoring uterine activity avoids the problems of size, fixation, and measurement accuracy exhibited by the conventional tocodynamometer technique.

Abstract translation: 通过通过（14,16）光穿过患者的腹壁感测（13）子宫活动，并检测（12）从腹部组织反射的光。 反射光的强度随患者子宫收缩状态而变化。 使用光线来监测子宫活动，避免了传统的心脏计量技术显示尺寸，固定和测量精度的问题。

公开(公告)号：WO1996039922A1

公开(公告)日：1996-12-19

申请号：PCT/US1996004502

申请日：1996-04-02

Applicant: OPTIX LP

Inventor： OPTIX LP ,  BLOCK, Myron, J. ,  SODICKSON, Lester

IPC: A61B05/00

CPC classification number: A61B5/14532 ,  A61B5/0059 ,  A61B5/14546 ,  A61B5/14558 ,  G01N21/359 ,  G01N21/4795 ,  G01N21/49 ,  G01N2021/3137

Abstract: An improved method and apparatus for use in optical testing of concentration in samples has been developed. The apparatus restricts the solid angle of illumination and the solid angle of detection to eliminate a high proportion of the scattered radiation while allowing the ballistic radiation and the snake-like radiation to be transmitted. In samples which contain multiple scattering centers, this allows less correction for variations in effective pathlength and allows easier calibration of the apparatus. The use of polarized radiation as a means of minimizing scattered radiation in the sample is also disclosed. In a second embodiment the detector collects only polarized radiation while excluding depolarized (multiple scattered) radiation. The radiation preferrably is chosen to be in the 700-1500 nm wavelength range. The sample preferrably is a portion of a mammalian body, the analyte to be analyzed is selected from the group consisting of glucose, glucose identifying substances, mixtures thereof or from the group consisting of hemoglobin, deoxyhemoglobin and mixtures thereof. The concentration measurement can be used to derive oxygen saturation of the blood.

Abstract translation: 已经开发了用于样品中浓度的光学测试的改进的方法和装置。 该装置限制了立体照明角度和立体检测角度，以消除散射辐射的高比例，同时允许弹道辐射和蛇状辐射传播。 在包含多个散射中心的样品中，这样可有效地校正光束长度的变化，并允许更容易校准仪器。 还公开了使用偏振辐射作为使样品中的散射辐射最小化的手段。 在第二实施例中，检测器仅收集偏振辐射，同时排除去极化（多散射）辐射。 辐射优选地选择在700-1500nm波长范围内。 样品优选地是哺乳动物体的一部分，待分析的分析物选自葡萄糖，葡萄糖鉴定物质，其混合物或由血红蛋白，脱氧血红蛋白及其混合物组成的组。 浓度测量可用于导出血液的氧饱和度。

公开(公告)号：WO1996035369A1

公开(公告)日：1996-11-14

申请号：PCT/SE1996000618

申请日：1996-05-10

Applicant: SYNECTICS MEDICAL AB ,  ESSEN-MÖLLER, Anders

Inventor： SYNECTICS MEDICAL AB

IPC: A61B05/00

CPC classification number: A61B5/14542 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/425

Abstract: A method and apparatus for determining the production of certain substances secreted in the body, for instance such substances as hydrochloric acid, bile salts, pancreas enzymes, pepsins, trypsins, porphyrins, nitrogen oxide and carbon dioxide. A dialyzable calibrating substance (21) is added to body fluid to a known extent, said calibrating substance containing the substance whose production shall be determined; the amount of calibrating substance dialyzed in a dialysis catheter in time is determined, the amount of substance whose production shall be determined dialyzed in the dialysis catheter in time is determined and a quotient (F(t)) between the added and dialyzed quantities of calibrating substance in time is determined and is correlated with a corresponding quotient (G(t)) for the substance whose production shall be determined, so as to determine said production.

Abstract translation: 用于测定体内分泌的某些物质的产生的方法和装置，例如盐酸，胆汁盐，胰酶，胰蛋白胨，胰蛋白胨，卟啉，氮氧化物和二氧化碳等物质。 将可透析校正物质（21）以已知程度添加到体液中，所述校准物质含有测定其生产的物质; 确定在透析导管中及时透析的校准物质的量，确定在透析导管中及时确定透析的生产量的物质的量，并且校准的添加量和透析量之间的商（F（t）） 物质在时间上被确定，并与其生产确定的物质的相应商（G（t））相关，以便确定所述生产。

公开(公告)号：WO1996034564A1

公开(公告)日：1996-11-07

申请号：PCT/US1996002437

申请日：1996-03-04

Applicant: MARKS, Lloyd, A.

IPC: A61B05/00

CPC classification number: A61B5/02141 ,  A61B5/02233

Abstract: A multiple blood pressure cuff system comprises a plurality of inflatable cuffs (12a-12e) of a range of widths and lengths which collectively share a common pressure source (14) and a common pressure measuring device (16). A manifold (18) pneumatically connects each cuff (12a-12e) to the common pressure source (14), pressure measuring device (16), and stopcock valves (20a-20e) allow airflow to be directed to the particular cuff in use. A mounting board (24) is provided for affixing the system to a wall or cabinet and for conveniently supporting and displaying the cuffs (12a-12e) that are not in use.

Abstract translation: 多血压袖带系统包括多个宽度和长度范围的可充气袖口（12a-12e），其共同共同的公共压力源（14）和公共压力测量装置（16）。 歧管（18）将每个箍（12a-12e）气动地连接到公共压力源（14），压力测量装置（16）和活塞阀（20a-20e），使气流在使用中被引导到特定的袖带。 提供安装板（24），用于将系统固定在墙壁或机柜上，并且便于支撑和显示未使用的袖带（12a-12e）。

公开(公告)号：WO1996032882A1

公开(公告)日：1996-10-24

申请号：PCT/US1996003349

申请日：1996-03-12

Applicant: HEARTPORT, INC.

Inventor： HEARTPORT, INC. ,  STEVENS, John, H. ,  REITZ, Bruce, A. ,  ROTH, Alex, T. ,  PETERS, William, S. ,  GIFFORD, Hanson, S.

IPC: A61B05/00

CPC classification number: A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/06061 ,  A61B17/2909 ,  A61B17/320016 ,  A61B17/3211 ,  A61B17/3417 ,  A61B17/3468 ,  A61B18/1442 ,  A61B18/1482 ,  A61B18/1492 ,  A61B90/37 ,  A61B90/50 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00349 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623 ,  A61B2017/00867 ,  A61B2017/00907 ,  A61B2017/0243 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/2943 ,  A61B2017/2946 ,  A61B2017/306 ,  A61B2017/3405 ,  A61B2017/3486 ,  A61B2017/3492 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00291 ,  A61B2018/00363 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2018/00898 ,  A61B2018/00982 ,  A61B2018/1465 ,  A61F2/2427 ,  A61M25/1011 ,  A61M39/0247 ,  A61M2025/028 ,  A61M2039/0279 ,  A61M2039/0297 ,  A61M2205/3344 ,  A61M2205/3355 ,  A61M2205/366 ,  Y10S623/904

Abstract: Devices, systems, and methods are provided for accessing the interior of the heart, and performing procedures therein while the heart is beating. A tubular access device (22) is positioned through an intercostal space and through a muscular wall of the heart. The access device (22) includes a balloon or flange for sealing (32) the penetration to prevent leakage of blood. An obturator (52) is positionable in the access device, and includes cutting means (60) located at its distal end. Elongated instruments are introduced through the access device to perform surgical procedures including septal device repair, ablation, and electrophysiological mapping.

Abstract translation: 提供了用于访问心脏内部的装置，系统和方法，以及在心脏跳动时执行其中的程序。 管状进入装置（22）通过肋间空间并通过心脏的肌肉壁定位。 进入装置（22）包括用于密封（32）穿透以防止血液泄漏的气囊或凸缘。 闭塞器52位于进入装置中，并且包括位于其远端的切割装置（60）。 通过进入装置引入细长的仪器以执行外科手术，包括中隔装置修复，消融和电生理测绘。

公开(公告)号：WO1996026670A1

公开(公告)日：1996-09-06

申请号：PCT/US1996000975

申请日：1996-01-24

Applicant: MEDTRONIC, INC.

Inventor： MEDTRONIC, INC. ,  HALPERIN, Louis, E. ,  MIESEL, Keith, A. ,  UFFORD, Keith, A. ,  SVENSK, James, R. ,  PATRICK, Timothy ,  HASSLER, Beth, Anne, H. ,  VARRICHIO, Anthony, J.

IPC: A61B05/00

CPC classification number: A61B5/0031 ,  A61B5/7217 ,  A61B2560/0257 ,  A61B2562/0247 ,  A61N1/3655 ,  A61N1/36564 ,  Y10S977/90 ,  Y10S977/905

Abstract: An endocardial lead (12) for implantation in a right heart chamber (RV) for responding to blood pressure and temperature and providing modulated pressure and temperature related signals to an implanted or external hemodynamic monitor (100) and/or cardiac pacemaker or pacemaker/cardioverter/defibrillator. The lead (12) has a sensor module (20) formed in its distal end and is coupled to a monitor (100) that powers a sensor circuit in the sensor module. The sensor module is formed with a pickoff capacitor (Cp) that changes capacitance with pressure changes and a reference capacitor (Cp) that is relatively insensitive to pressure changes. The sensor circuit provides charge current that changes with temperature variation at the implant site, alternately charges and discharges the two capacitors, and provides timing pulses having distinguishable parameters at the end of each charge cycle that are transmitted to a demodulator (150). The demodulator (150) detects and synchronizes the timing pulses and derives pressure and temperature analog voltage values representative of the intervals between the timing pulses which are digitized and stored in the monitor. The monitor may also be coupled with other sensors (106, 152) for measuring and storing related patient body parameters, e.g. blood gas, ECG, and patient activity.

Abstract translation: 一种用于植入右心室（RV）以响应血压和温度并向植入或外部血液动力学监测器（100）和/或心脏起搏器或起搏器/心律转复器提供调制的压力和温度相关信号的心内膜引线（12） /除颤器。 引线（12）具有形成在其远端的传感器模块（20），并耦合到对传感器模块中的传感器电路供电的监视器（100）。 传感器模块由传感器电容器（Cp）形成，该电容器可以改变压力变化的电容和对压力变化相对不敏感的参考电容器（Cp）。 传感器电路提供随着植入部位温度变化而变化的充电电流，交替地对两个电容器进行充电和放电，并且在每个充电周期结束时提供发送到解调器（150）的具有可区分参数的定时脉冲。 解调器（150）检测并同步定时脉冲，并且导出代表数字化并存储在监视器中的定时脉冲之间的间隔的压力和温度模拟电压值。 监视器还可以与其他传感器（106,152）耦合，用于测量和存储相关的患者身体参数，例如， 血气，心电图和患者活动。

公开(公告)号：WO1996025087A1

公开(公告)日：1996-08-22

申请号：PCT/US1995015670

申请日：1995-12-01

Applicant: MEDWAVE, INC.

Inventor： MEDWAVE, INC. ,  ARCHIBALD, G., Kent ,  CURAN, Timothy, G. ,  DANIELSON, Orland, H. ,  POLIAC, Marius, O. ,  THEDE, Roger, C.

IPC: A61B05/00

CPC classification number: A61B5/02116 ,  A61B2562/0247

Abstract: A device for supporting a sensing surface above an underlying artery of a patient includes a hold down assembly (36) and a sensor interface (38) pivotally coupled to the hold down assembly (36). The hold down assembly is secured at a spaced position relative to the underlying artery of the patient. The sensor interface (38) includes a flexible diaphragm (168), a compressible side wall (162, 164) and a mount (152). The flexible diaphragm (168) has an active portion (168b) for transmitting blood pressure pulses of the underlying artery. The compressible side wall (162, 164) encircles the active portion (168b) and has a top end and a bottom end. The bottom end (162, 164) is secured to the flexible diaphragm (168). The mount (152) is coupled to the top end of the compressible side wall (162, 164). The mount (152) has a connection located below the top end of the compressible side wall (162, 164) for receiving a movable member (128) of the hold down assembly (36) so that the movable member (128) may be pivotally coupled to the sensor interface (38) below the top end of the compressible side wall (162, 164).

Abstract translation: 用于支撑患者的下面动脉之上的感测表面的装置包括压紧组件（36）和枢转地联接到压紧组件（36）的传感器接口（38）。 按压组件固定在相对于患者的下面动脉的间隔位置处。 传感器接口（38）包括柔性隔膜（168），可压缩侧壁（162,164）和安装座（152）。 柔性隔膜（168）具有用于传递下面的动脉的血压脉冲的活动部分（168b）。 可压缩侧壁（162,164）围绕有效部分（168b）并且具有顶端和底端。 底端（162,164）固定到柔性隔膜（168）上。 安装件（152）联接到可压缩侧壁（162,164）的顶端。 安装件（152）具有位于可压缩侧壁（162,164）的顶端下方的连接件，用于接收压紧组件（36）的可动构件（128），使得可移动构件（128）可枢转 耦合到可压缩侧壁（162,164）的顶端下方的传感器接口（38）。

公开(公告)号：WO1996023441A1

公开(公告)日：1996-08-08

申请号：PCT/US1996001226

申请日：1996-01-26

Applicant: MICROVENA CORPORATION

Inventor： MICROVENA CORPORATION ,  ERICKSON, David, S. ,  MAZZOCCHI, Rudy

IPC: A61B05/00

CPC classification number: A61M25/09 ,  A61M2025/09166 ,  A61M2025/09175

Abstract: An embodiment of the invention provides a guidewire having a coil which comprises at least a distal coil segment (24) and a proximal coil segment (22), one of the coil segments being more radiopaque than at least one of the other coil segments. An elongate wire (14) may extend within the lumen of the coil. In a two segment coil, the distal end of the distal coil segment is attached to the wire (14) and the proximal end of the distal coil segment is attached to the distal end of the proximal coil segment while the proximal end of the proximal coil segment is attached to the wire (14).

Abstract translation: 本发明的一个实施例提供了一种具有线圈的导丝，该线圈至少包括远侧线圈段（24）和近端线圈区段（22），其中一个线圈段比其他线圈段中的至少一个更不透射线。 细长线（14）可以在线圈的内腔内延伸。 在两段线圈中，远侧线圈段的远端附接到线（14），并且远端线圈段的近端附接到近端线圈段的远端，而近端线圈的近端 片段附接到线（14）。

公开(公告)号：WO1996022727A1

公开(公告)日：1996-08-01

申请号：PCT/FR1996000141

申请日：1996-01-26

Applicant: SABIN, Pierre

IPC: A61B05/00

CPC classification number: A61B5/04001 ,  A61B5/0031 ,  A61B5/6865 ,  A61F2250/0001

Abstract: A medical apparatus comprising a transcutaneous device (3) comprising a base (6) having means for attachment to a bone (5) of the organism and sealed connection means fitted either with a temporary stopper (7) or a transcutaneous pillar (8) containing electrical connections (27) complementary to the electrical connections (21) incorporated in the base (6), the base also comprising a sealed bacteriological protective membrane (34) which can be perforated by at least electrically conductive pins (30) which the said electrical connections (27) comprise.

Abstract translation: 一种包括经皮装置（3）的医疗装置，包括具有附接到所述生物体的骨骼（5）的装置的基部（6）和用临时塞子（7）或经皮柱（8）装配的密封连接装置，所述临时塞子（7）或经皮支柱（8） 电连接（27）与引入基座（6）中的电气连接（21）互补，基座还包括密封的细菌保护膜（34），该密封细菌保护膜可以由至少导电销（30）穿孔， 连接（27）包括。

公开(公告)号：WO1996020637A1

公开(公告)日：1996-07-11

申请号：PCT/US1995015063

申请日：1995-11-16

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DUDAR, Thomas, E. ,  GRAHAM, Peter

IPC: A61B05/00

CPC classification number: A61M25/0643 ,  A61B5/15003 ,  A61B5/150656 ,  A61B5/150732 ,  A61B5/154 ,  A61M5/3271 ,  A61M25/0631

Abstract: This invention is a protective shield (18) for a blood sampling unit that is movably engaged to an adapter (10) having a needle (12) attached. The shield attaches to a tube holder when the needle is covered by the shield. Longitudinal grooves (56) on the adapter (52) guide the shield between a first position, covering the needle, and a second position, exposing the needle. The shield can be locked in either the first position or the second position. The blood sampling unit is safely disassembled or re-assembled when the needle is covered by the shield. In an embodiment of the invention, a tip protector (42), removably attached to the adapter, extends through the length of the tube holder (44) to prevent needlesticks. The blood sampling unit and the tube holder can be assembled and disassembled when the tip protector is attached to the adapter, covering the needle. The tip protector is removed during a clinical procedure and then replaced after the clinical procedure is finished.

Abstract translation: 本发明是一种用于采血单元的保护罩（18），其可移动地接合到具有附接的针（12）的适配器（10）。 当针被护罩覆盖时，护罩连接到管座。 适配器（52）上的纵向槽（56）引导屏蔽在覆盖针的第一位置和第二位置之间，使针露出。 屏蔽可以锁定在第一位置或第二位置。 当针被护罩覆盖时，采血单元可以安全地拆卸或重新组装。 在本发明的一个实施例中，可移除地附接到适配器的尖端保护器（42）延伸穿过管保持器（44）的长度以防止针刺。 当尖端保护器附接到适配器上时，采血单元和管座可以组装和拆卸，覆盖针头。 在临床过程中将尖端保护器移除，然后在临床手术完成后更换。