公开(公告)号：AU2562695A

公开(公告)日：1995-12-18

申请号：AU2562695

申请日：1995-05-09

Applicant: BASF AG

Inventor： KARL ULRICH ,  MULLER STEFAN ,  POTZOLLI BERND DE

IPC: C07B61/00 ,  C07C227/18 ,  C07C229/12 ,  C07C269/06 ,  C07C271/22 ,  C07C323/59

Abstract: A process for preparing N-protected N-alkylated amino acids of the formula I:in which the substituents have the meanings stated in the description, comprises mixing a compound of the formula IIwith a solution of potassium tert-butanolate in a non-protic organic solvent, and subsequently adding a C1-2-alkyl halide.

公开(公告)号：AU2408295A

公开(公告)日：1995-11-29

申请号：AU2408295

申请日：1995-04-26

Applicant: BASF AG

Inventor： AMBERG WILHELM ,  BERNARD HARALD ,  BUSCHMANN ERNST ,  HAUPT ANDREAS ,  JANITSCHKE LOTHAR ,  JANSSEN BERND ,  KARL ULRICH ,  KLING ANDREAS ,  MULLER STEFAN ,  POTZOLLI BERND DE ,  RITTER KURT ,  THYES MARCO ,  ZIERKE THOMAS

IPC: A61K38/00 ,  A61P35/00 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06

Abstract: Compounds of the formulawhere R1, R2, R3 and R4 have the meaning stated in the description, and a process for preparing them are described. The compounds are suitable as starting material for synthesizing substances which are active against tumors.