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公开(公告)号:EP2368890B9
公开(公告)日:2013-10-30
申请号:EP11160830.3
申请日:2010-06-10
Applicant: AbbVie Bahamas Limited
Inventor: Randolph, John T. , Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachin V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Charles A. , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary E. , YI, Gao
IPC: C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC classification number: C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
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公开(公告)号:EP2337781A2
公开(公告)日:2011-06-29
申请号:EP10724656.3
申请日:2010-06-10
Applicant: Abbott Laboratories
Inventor: RANDOLPH, John T. , DEGOEY, David A. , KATI, Warren M. , HUTCHINS, Charles W. , DONNER, Pamela L. , KRUEGER, Allan C. , MOTTER, Christopher E. , NELSON, Lissa T. , PATEL, Sachin V. , MATULENKO, Mark A. , KEDDY, Ryan G. , JINKERSON, Tammie K. , SOLTWEDEL, Todd N. , HUTCHINSON, Douglas K. , FLENTGE, Charles A. , WAGNER, Rolf , MARING, Clarence J. , TUFANO, Michael D. , BETEBENNER, David A. , ROCKWAY, Todd W. , LIU, Dachun , PRATT, John K. , LAVIN, Michael J. , SARRIS, Kathy , WOLLER, Kevin R. , WAGAW, Seble H. , CALIFANO, Jean C. , LI, Wenke , CASPI, Daniel.D. , BELLIZZI, Mary, E.
IPC: C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC classification number: C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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143.Preparation of nitro compounds by vapor phase nitration of olefins 失效
Title translation: 通过蒸气相氮化合物制备硝基化合物公开(公告)号:EP0174600B1
公开(公告)日:1988-03-09
申请号:EP85111167.4
申请日:1985-09-04
Applicant: W.R. GRACE & CO.
Inventor: Wang, Shue-Cieh Paul
CPC classification number: C07C201/06 , C07C205/02
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公开(公告)号:EP0085328B1
公开(公告)日:1986-11-12
申请号:EP83100324.9
申请日:1983-01-15
Applicant: W.R. GRACE & CO.
Inventor: Sherwin, Martin B.
CPC classification number: C07C201/06 , C07C201/08 , C07C205/02
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145.Preparation of nitro compounds by vapor phase nitration of oxygenated hydrocarbons 失效
Title translation: 通过蒸气相氮化处理的硝基化合物制备硝基化合物公开(公告)号:EP0146203A3
公开(公告)日:1986-03-12
申请号:EP84305503
申请日:1984-08-13
Applicant: W.R. GRACE & CO.
Inventor: Wang, Shu-chieh Paul , Sherwin, Martin B.
CPC classification number: C07C45/29 , C07C201/06 , C07C47/06 , C07C205/02
Abstract: Nitro compounds are selectively formed by contacting, at elevated temperature and pressure and in a homogeneous gas phase, an organic oxygenated hydrocarbon having from two to ten carbon atoms with N0 2 alone or in the presence of oxygen and/or water.
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146.Trisubstituted heterocycles as replication inhibitors of hepatitis C virus HCV 有权
Title translation: 三 - 取代的杂环如丙型肝炎病毒HCV复制的抑制剂公开(公告)号:EP2628481B1
公开(公告)日:2016-02-24
申请号:EP13167828.6
申请日:2010-06-10
Applicant: AbbVie Bahamas Ltd.
Inventor: Randolph, John T. , Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger Allan C. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachin V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel.D. , Bellizzi, Mary, E. , Gao, Yi
IPC: A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4439 , A61P31/14 , C07D401/14 , C07D417/14 , C07D403/14
CPC classification number: C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
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公开(公告)号:EP2853531A3
公开(公告)日:2015-08-12
申请号:EP14190636.2
申请日:2010-06-10
Applicant: AbbVie Bahamas Ltd.
Inventor: Randolph, John T. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Rolf , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Degoey, David A. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary, E. , Gao, Yi , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E , Nelson, Lissa T. , Patel, Sachin V.
IPC: C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC classification number: C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
Abstract translation: 描述了有效抑制丙型肝炎病毒(“HCV”)复制的化合物。 本发明还涉及制备这些化合物的方法,包含这些化合物的组合物,以及使用这些化合物治疗HCV感染的方法。
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公开(公告)号:EP2368890B1
公开(公告)日:2013-04-17
申请号:EP11160830.3
申请日:2010-06-10
Applicant: AbbVie Bahamas Limited
Inventor: Randolph, John T. , Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachin V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Charles A. , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Liu, Dachun , Pratt, John K. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary E. , YI, Gao
IPC: C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC classification number: C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
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公开(公告)号:EP2368890A1
公开(公告)日:2011-09-28
申请号:EP11160830.3
申请日:2010-06-10
Applicant: Abbott Laboratories
Inventor: Randolph, John T. , Degoey, David A. , Kati, Warren M. , Hutchins, Charles W. , Donner, Pamela L. , Krueger, Allan C. , Motter, Christopher E. , Nelson, Lissa T. , Patel, Sachin V. , Matulenko, Mark A. , Keddy, Ryan G. , Jinkerson, Tammie K. , Soltwedel, Todd N. , Hutchinson, Douglas K. , Flentge, Charles A. , Wagner, Charles A. , Maring, Clarence J. , Tufano, Michael D. , Betebenner, David A. , Rockway, Todd W. , Liu, Dachun , Pratt, John K. , Lavin, Michael J. , Sarris, Kathy , Woller, Kevin R. , Wagaw, Seble H. , Califano, Jean C. , Li, Wenke , Caspi, Daniel D. , Bellizzi, Mary E.
IPC: C07D403/14 , C07D401/14 , C07D417/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/4196 , A61K31/4439 , A61P31/14
CPC classification number: C07F9/65583 , C07C33/26 , C07C201/06 , C07C205/19 , C07D207/08 , C07D207/09 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D453/00 , C07D471/04 , C07D491/113 , C07K5/06
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
Abstract translation: 描述了有效抑制丙型肝炎病毒(“HCV”)复制的化合物。 本发明还涉及制备这种化合物的方法,包含这些化合物的组合物,以及使用这些化合物治疗HCV感染的方法。
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150.PROCEDE DE NITROSATION D'UN COMPOSE PHENOLIQUE SUBSTITUE PAR UN GROUPEMEMT ELECTRO-ATTRACTEUR ET SON UTILISATION 失效
Title translation: 亚硝化方法逐一吸电子基团取代的酚化合物,和使用公开(公告)号:EP0922025A1
公开(公告)日:1999-06-16
申请号:EP97933724.0
申请日:1997-07-11
Applicant: RHODIA CHIMIE
Inventor: METIVIER, Pascal
CPC classification number: C07B43/02 , C07C201/00 , C07C201/06 , C07C205/60 , C07C207/04
Abstract: The invention concerns a method of nitrosation of a phenolic compound substituted by an electro-attracting group.The invention also concerns a method of nitration of a phenoic compound substituted by an electro-attracting group. The nitrosation method is characterised in that it consists in effecting the nitrosatio n of the said compound in presence of sulphuric acid; the concentration of the sulphuric acid being at least 60 % by weight, then optionally in effecting the separation of the resulting nitrosated compound. The invention also concerns the oxidation of the resulting p-nitrosated phenolic compound for obtaining the corresponding nitrated compound.
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