Abstract:
An analysis system (e.g., LIBS) includes a laser source generating a laser beam, a movable optic configured to move said laser beam to multiple locations on a sample, and a spectrometer responsive to photons emitted by the sample at those locations and having an output. A controller is responsive to a trigger signal and is configured in a moving spot cycle to adjust the moveable optic, activate the laser source sequentially generating photons at multiple locations on the sample, and process the spectrometer output at each location.
Abstract:
A mechanism that allows for precise motion of the optics of an interferometer is comprised by two or more diaphragm flexures having high lateral stiffness, creating a superior performing Michelson interferometer. When coupled with precise precision control of a mirror surface and a reference laser, the above creates a superior performing Fourier transform spectrometer.
Abstract:
An analysis system includes a laser source generating a laser beam for creating a plasma at a location on a sample. A spectrometer is responsive to photons emitted by the sample at said location and has an output. At least one nozzle is configured to deliver inert gas from a source locally to the location on the sample. A controller is responsive to a trigger signal and is configured to activate the laser source generating a series of laser pulses, open a valve to purge the location locally on the sample, and close the valve after one or more laser pulses.
Abstract:
Die vorliegende Erfindung betrifft ein Verfahren und eine Anordnung zur Fourier- Transformations-Spektroskopie, insbesondere auch zur bildgebenden Strahlungsquellen- und Stoff-Analyse aller Aggregatzustände sowie zur bildgebenden In-vivo-Gewebe-Diagnostik, einschließlich von Tumorgewebe. Die Anordnung ist insbesondere auch als mobiler Scout-Sensor oder als eine hochparallelisierte fest installierte Analyse-Station im jeweils dafür geeigneten Spektralbereich ausgebildet. Erfindungsgemäß wird mittels einer spektral breitbandigen Quelle elektromagnetischer Strahlung eine Bestrahlung mindestens eines länglichen Bereiches in den beiden Aperturflächen (A1, A2) des genutzten Zweistrahl-Interferometers mit Längsrichtung des bestrahlten länglichen Bereiches senkrecht zur Schnittebene V-M durchgeführt. Dabei sind die Endreflektoren in Hybrid-Form mit partiellen Retro-Reflexionseigenschaften ausgebildet. Es ergibt sich ein Vorteil für die Robusfheit des Zweistrahl-Interferometers auch unter widrigen Bedingungen, da unerwünschter Tilt und unerwünschte Shear von Wellenfronten eingeschränkt und/oder auch zur numerischen Kompensation erfasst werden. Somit können zuverlässige Interferogramm-Daten zur Spektrenberechnung bereitgestellt werden.
Abstract:
A system and method of dynamically localizing a measurement of parameter characterizing tissue sample with waves produced by spectrometric system at multiple wavelengths and detected at a fixed location of the detector of the system. The parameter is calculated based on impulse response of the sample, reference data representing characteristics of material components of the sample, and path lengths through the sample corresponding to different wavelengths. Dynamic localization is effectuated by considering different portions of a curve representing the determined parameter, and provides for the formation of a spatial map of distribution of the parameter across the sample. Additional measurement of impulse response at multiple detectors facilitates determination of change of the measured parameter across the sample as a function of time.
Abstract:
The present invention relates generally to a methodology of determining the concentration of the types of melanin, either eumelanin or pheomelanin, in the skin wherein the process for such determination is non-invasive and based on digital signal and image analysis of hyperspectral sensing and multi-spectral data.
Abstract:
Reflectance systems and methods are described that under-fill the collection fiber of a host spectrometer both spatially and angularly. The under- filled collection fiber produces a response of fiber-based spectrometers that is relatively insensitive to sample shape and position.