公开(公告)号：KR1020140065535A

公开(公告)日：2014-05-30

申请号：KR1020120129613

申请日：2012-11-15

Applicant: 대한민국(농촌진흥청장) ,  충북대학교 산학협력단

Inventor： 장기창 ,  서우덕 ,  한상익 ,  나지은 ,  오성환 ,  강현중 ,  김병주 ,  강항원 ,  남민희 ,  김대중 ,  김태명 ,  심태진

IPC: A61K36/899 ,  A61K31/352 ,  A61K31/35 ,  A61P29/00

CPC classification number: A61K31/352 ,  A61K36/899 ,  Y10S514/857 ,  Y10S514/886 ,  Y10S514/894 ,  Y10S514/914

Abstract: The present invention relates to an extract containing a polyphenol-based compound derived from sorghum and sorghum by-products and a pharmaceutical composition for prevention and treatment of inflammatory diseases containing the same as an active ingredient. More specifically, the present invention relates to: an extract containing a polyphenol-based compound derived from sorghum and sorghum by-products, which has a useful effect on prevention and treatment of inflammatory disease by separating a polyphenol-based compound showing an anti-inflammatory effect from a sorghum extract, and which can be used for the ingredients of food and medicines as well as a natural anti-inflammatory drug, etc.; and a pharmaceutical composition for prevention and treatment of inflammatory diseases containing the same as an active ingredient.

Abstract translation: 本发明涉及含有由高粱和高粱副产物衍生的多酚类化合物的提取物和用于预防和治疗含有其作为活性成分的炎性疾病的药物组合物。 更具体地说，本发明涉及：含有源自高粱和高粱副产物的多酚类化合物的提取物，其通过分离显示抗炎药物的多酚类化合物对预防和治疗炎性疾病有有效的作用 高粱提取物的作用，可用于食品和药物的成分以及天然抗炎药物等; 以及用于预防和治疗含有其作为活性成分的炎性疾病的药物组合物。

公开(公告)号：KR1020140056708A

公开(公告)日：2014-05-12

申请号：KR1020120121907

申请日：2012-10-31

Applicant: 대한민국(농촌진흥청장)

Inventor： 조준현 ,  이종희 ,  김상열 ,  송유천 ,  이지윤 ,  오성환 ,  손영보 ,  한상익 ,  여운상 ,  박동수 ,  남민희

IPC: A21D13/04 ,  A21D15/02 ,  A23L7/10

CPC classification number: A21D13/04 ,  A21D13/44 ,  A21D15/02

Abstract: The present invention relates to a method for manufacturing rice crepe, and more specifically, to a method for manufacturing rice crepe using the mixture of rice and tapioca starch instead of wheat flour. The method for manufacturing rice crepe according to one embodiment of the present invention includes a step of immersing rice into water, a step of crushing the immersed rice and obtaining rice powder, a step of obtaining dough by mixing the rice powder with the tapioca starch and adding water and salt, and a step of steaming the dough.

Abstract translation: 本发明涉及一种制造米绉的方法，更具体地说，涉及使用米和木薯淀粉代替小麦粉的混合物制造稻绉的方法。 根据本发明的一个实施方案的制造米绉的方法包括将米浸入水中的步骤，将浸米浸泡并获得米粉的步骤，通过将米粉与木薯淀粉混合获得面团的步骤和 加入水和盐，以及蒸熟面团的步骤。

公开(公告)号：KR101376231B1

公开(公告)日：2014-03-26

申请号：KR1020110020660

申请日：2011-03-08

Applicant: 대한민국(농촌진흥청장)

Inventor： 장기창 ,  한상익 ,  서우덕 ,  나지은 ,  오성환 ,  최경진 ,  강항원 ,  하태정

IPC: A61K36/8998 ,  A61K31/37 ,  A61P31/16 ,  A61P31/00

Abstract: 본 발명은 뉴라미니데이즈 억제활성을 가지는 새싹보리 추출물 및 폴리페놀계 화합물에 관한 것으로서, 보다 상세하게는 새싹보리 유래 폴리페놀계 화합물을 추출하여 분리하고, 이의 뉴라미니데이즈 억제 활성을 확인하여 인플루엔자 바이러스의 예방, 치료 등에 적용할 수 있는 조성물에 관한 것이다.
본 발명은 인플루엔자 바이러스 표면 항원인 동시에 새로 생성된 바이러스를 세포밖으로 방출하는데 중요한 역할을 담당하는 효소인 뉴라미니데이즈에 대하여 새싹보리의 폴리페놀계 화합물들이 강한 억제효과가 있음을 확인함으로써 생물의약, 건강기능 식품산업과 식·의약분야 및 가축 사료 첨가제 분야에서 새싹보리의 활용성을 증진시킬 수 있을 것으로 기대된다.

公开(公告)号：KR1020140017818A

公开(公告)日：2014-02-12

申请号：KR1020120084430

申请日：2012-08-01

Applicant: 대한민국(농촌진흥청장) ,  연세대학교 원주산학협력단

Inventor： 서우덕 ,  장기창 ,  한상익 ,  나지은 ,  오성환 ,  송유천 ,  강항원 ,  남민희 ,  김종배 ,  김사현 ,  박민

IPC: A61K36/899 ,  A61P1/04 ,  A61P1/00

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating Helicobacter pylori infectious diseases which includes extract of black rice or black rice solvent fractions as an active ingredient and a method for manufacturing black rice solvent fractions. More specifically, the active ingredients of the black rice extract or black rice derived cyanidin-3-O-glucoside black rice fractions show activities of growth inhibition of the Helicobacter pylori, inhibition of Helicobacter pylori urease, and toxin secretion inhibition of CagA, VacA, SecA, and are safe and natural black rice derived materials so that active ingredients of the black rice extract or black rice derived cyanidin-3-O-glucoside black rice fractions can be used as the pharmaceutical composition, health supplement, drink and additives for preventing or treating the Helicobacter pylori which are safe, have low toxicity, and inhibits the generation of resistant bacteria caused by abusing antibiotics.

Abstract translation: 本发明涉及一种用于预防或治疗幽门螺杆菌感染性疾病的药物组合物，其包括黑米或黑米溶剂级分的提取物作为活性成分，以及黑米溶剂级分的制造方法。 更具体地说，黑米提取物或黑米衍生的花青素-3-O-葡萄糖苷黑米级部分的活性成分显示了幽门螺旋杆菌的生长抑制活性，幽门螺杆菌脲酶的抑制以及CagA，VacA的毒素分泌抑制， SecA，并且是安全和天然的黑米衍生材料，使得黑米提取物或黑米衍生的花青素-3-O-葡萄糖苷黑米级分的活性成分可用作药物组合物，健康补充剂，饮料和预防添加剂 或治疗安全的幽门螺杆菌，具有低毒性，并且抑制由滥用抗生素引起的抗性细菌的产生。

公开(公告)号：KR101296208B1

公开(公告)日：2013-08-13

申请号：KR1020120081932

申请日：2012-07-26

Applicant: 대한민국(농촌진흥청장) ,  경북대학교 산학협력단

Inventor： 한상익 ,  장기창 ,  서우덕 ,  나지은 ,  오성환 ,  최경진 ,  강항원 ,  남민희 ,  최진현

IPC: D01F1/10 ,  D01D5/00 ,  D01F6/14 ,  D01D1/02 ,  A61L15/10 ,  A61L26/00

CPC classification number: D01F1/103 ,  A61L15/10 ,  A61L26/0014 ,  D01D1/02 ,  D01D5/0015 ,  D01F6/14

Abstract: PURPOSE: A polyvinyl alcohol nanofiber which contains sorghum pigment is provided to show high antibiotic material and be used as wound coating flux which is medical material due to no cytotoxicity. CONSTITUTION: The sorghum by-product extract is the golden chalsusu stem extract and the golden chalsusu stem extract. The component of the sorghum extract or the sorghum by-product extract is chemical formula 1 or chemical formula 2.

Abstract translation: 目的：提供含有高粱颜料的聚乙烯醇纳米纤维，以显示高抗生素材料，并且由于没有细胞毒性而用作医疗材料的伤口涂层助焊剂。 构成：高粱副产品提取物是金黄色素提取物和金黄色素提取物。 高粱提取物或高粱副产物提取物的组分是化学式1或化学式2。

公开(公告)号：KR101211530B1

公开(公告)日：2012-12-13

申请号：KR1020110027174

申请日：2011-03-25

Applicant: 대한민국(농촌진흥청장)

Inventor： 조준현 ,  송유천 ,  오성환 ,  이종희 ,  이지윤 ,  김상열 ,  박수권 ,  한상익 ,  정국현 ,  박동수 ,  여운상 ,  이기환 ,  강항원

IPC: A23L7/10 ,  A23P1/08

Abstract: 본발명은쌀쌈의제조방법에관한것으로, 더욱상세하게는국내육성품종인밥쌀용쌀을물에침지한후 가수하여얻은분쇄물을건조하여쌀가루를얻고상기쌀가루를감자전분과배합하여물과소금을첨가한후 반죽하고상기반죽물을성형및 증숙한뒤 일정조건에서건조과정을거침으로써쌀쌈을제조하는방법에관한것이다.

公开(公告)号：KR1020110088304A

公开(公告)日：2011-08-03

申请号：KR1020100008156

申请日：2010-01-28

Applicant: 대한민국(농촌진흥청장)

Inventor： 한상익 ,  하태정 ,  장기창 ,  서우덕 ,  이제봉 ,  고종민 ,  오성환 ,  김상열 ,  박동수 ,  조준현 ,  강항원 ,  정명근

IPC: G01N33/10 ,  G01N33/02 ,  G01N31/00 ,  G01N21/359

Abstract: PURPOSE: A non-destructive analysis method is provided to effectively analyze ingredient consisting of fatty acid of a grain. CONSTITUTION: A non-destructive analysis method for a fatty acid composition of a single granule comprises: a step of randomly selecting a plurality of prediction model development group and prediction model evaluation group; a step of measuring near infrared absorption spectrum of two groups; a step of randomly selecting grain granule sample among the prediction model development groups and measuring near infrared ray absorption spectrum; a step of pulverizing the granule sample and performing chemical analysis of fatty acid ingredients; and a step of applying primary and secondary derivatives to the absorption spectrum.

Abstract translation: 目的：提供一种非破坏性分析方法，有效分析由谷物脂肪酸组成的成分。 构成：单粒子脂肪酸组成的无损分析方法包括：随机选择多个预测模型开发组和预测模型评价组的步骤; 测量两组近红外吸收光谱的步骤; 在预测模型开发组中随机选择颗粒样品并测量近红外线吸收光谱的步骤; 粉碎颗粒样品并进行脂肪酸成分的化学分析的步骤; 以及将一次和二次衍生物应用于吸收光谱的步骤。

公开(公告)号：KR1020110085758A

公开(公告)日：2011-07-27

申请号：KR1020100005714

申请日：2010-01-21

Applicant: 대한민국(농촌진흥청장)

Inventor： 한상익 ,  장기창 ,  서우덕 ,  이제봉 ,  박수권 ,  남민희 ,  강항원 ,  오성환 ,  이기환 ,  박동수 ,  김상열 ,  황운하 ,  최경진

IPC: A61K36/899 ,  A61K31/37 ,  A61K31/7048 ,  A61P17/00

CPC classification number: A61K31/192 ,  A23L29/035 ,  A61K8/368 ,  A61K8/498 ,  A61K8/602 ,  A61K8/97 ,  A61K31/352 ,  A61K31/7048 ,  A61K36/8998 ,  A61K2236/33

Abstract: PURPOSE: A method for preparing extract derived from young barley leaf is provided to isolate novel ingredients and to be used as a functional material supply source. CONSTITUTION: A young barley leaf extract with an antioxidative activity is prepared using an organic solvent. The young barley leaf is collected in a length of 10-20 cm and is freeze-dried. The organic solvent is methanol or ethanol. The ethanol is 80-90 weight% ethanol solution. A composition for skin whitening or anti-aging contains the extract as an active ingredient. A health food for skin whitening or anti-aging contains the extract as an active ingredient. A solvent fraction of the extract contains one or more compounds selected from compound of chemical formulas 1-4.

Abstract translation: 目的：提供一种制备从年轻大麦叶提取的提取物的方法，用于分离新成分并用作功能材料供应源。 构成：使用有机溶剂制备具有抗氧化活性的年轻大麦叶提取物。 收集年轻的大麦叶，长度为10-20厘米，冷冻干燥。 有机溶剂为甲醇或乙醇。 乙醇为80-90重量％乙醇溶液。 用于皮肤美白或抗衰老的组合物含有提取物作为活性成分。 用于皮肤美白或抗衰老的保健食品含有提取物作为活性成分。 提取物的溶剂馏分含有一种或多种选自化学式1-4化合物的化合物。

公开(公告)号：KR101677478B1

公开(公告)日：2016-11-21

申请号：KR1020140160404

申请日：2014-11-17

Applicant: 대한민국(농촌진흥청장)

Inventor： 서우덕 ,  송유천 ,  조준현 ,  이종희 ,  한상익 ,  오성환 ,  나지은 ,  박지영 ,  심은영 ,  남민희

IPC: A23G1/48 ,  A23L1/30 ,  C07H17/065 ,  C07J53/00 ,  C07C229/08

Abstract: 본발명은 (a) 흑미또는흑미밥을기름에튀기거나볶는단계; 및 (b) 상기튀기거나볶은흑미또는흑미밥을초콜릿과혼합하여성형틀에부어성형하는단계를포함하는흑미를함유한항산화활성이증진된흑미초콜릿의제조방법에관한것이다. 본발명의흑미초콜릿의제조방법에의해제조된초콜릿은항산화활성을나타내는여러가지기능성물질들을함유하고있어, 항산화활성이일반초콜릿에비해뛰어나며, 초콜릿본연의향을해치지않으면서흑미의맛과향이조화되어전체적인선호도가향상되었다.

公开(公告)号：KR101644607B1

公开(公告)日：2016-08-03

申请号：KR1020140108940

申请日：2014-08-21

Applicant: 대한민국(농촌진흥청장) ,  연세대학교 원주산학협력단

Inventor： 서우덕 ,  장기창 ,  한상익 ,  나지은 ,  오성환 ,  송유천 ,  강항원 ,  남민희 ,  김종배 ,  김사현 ,  박민

IPC: A61K36/899 ,  A61K31/7048 ,  A61P1/04 ,  A61P31/04

Abstract: 본발명은흑미추출물또는흑미용매분획물을유효성분으로포함하는헬리코박터파이로리() 감염질환의예방또는치료용약학적조성물및 흑미용매분획물을제조하는방법에관한것이다. 특히흑미추출물또는흑미유래시아니딘 3-O-글루코사이드흑미분획물의유효성분은헬리코박터파이로리의생육억제활성, 헬리코박터파일로리유레이즈억제활성및 CagA, VacA, SecA의독소분비억제활성을나타내며, 흑미유래의안전한천연소재이므로인체에안전성, 저독성및 항생제남용에의한내성균발생을억제하는안전한헬리코박터파이로리예방또는치료용약학적조성물, 건강식품, 음료및 첨가물로유용하게이용될 수있다.