Abstract:
A micro-electrode array includes a substrate of a flexible material and one or more fine electrodes which are located on the substrate. The substrate includes a pattern which is located in a part of the substrate and reduces the thickness of the substrate by at least partly removing the substrate. A fine electrode array manufactured on a two dimensional plane is easily deformable into a three dimensional shape by the pattern which increases the flexibility of the substrate. For instance, the fine electrode array touches an object having a curved surface, thereby providing uniform contact according to the shape of an object when the fine electrode is inserted into a human body.
Abstract:
PURPOSE: An artificial retina system and a manufacturing method thereof are provided to obtain visual information and to stimulate the retina. CONSTITUTION: An artificial retina system comprises a substrate(300), a nanowire optical detector(301), a microelectrode array(302), and a power source(303). The substrate is patterned by lithographic processing. The nanowire optical detector comprises a nanowire in which resistance changes according to applied light. The microelectrode array stimulates retina cells and is placed to contact the retina cells. The power source supplies power for stimulating the retina cells to the nanowire optical detector and microelectrode array.
Abstract:
PURPOSE: A drug delivery system containing a layer structure with drug layers and polymer layers alternatively laminated is provided to highly maintain drug concentration of a target site and to easily control drug release rate. CONSTITUTION: A drug delivery system comprises: a core of a layer structure containing drug layers(110) and polymer layers(111) which are alternatively laminated; and a polymer outer layer(100) which surround the core and comprises an opening part. The drug delivery system further comprises a polymer cover(120) for covering the opening part. The structure inside the core has 2-10 layers. The polymer of the outer layer contains poly-caprolactone(PCL) or L-poly-lactide(LPLA). [Reference numerals] (100) Drug delivery system outer layer; (110) Drug layer; (111) Polymer layer; (120) Drug delivery system cover
Abstract:
본 발명은 표면에 미생물이 선택적으로 흡착된 이동성 마이크로 소자를 제작하는 방법으로서, 상기 마이크로 소자의 표면 에너지를 부분적 또는 전체적으로 조절하여 마이크로 소자에 흡착되는 미생물의 공간적 분포 또는 밀집도를 제어하는 것을 포함하는 방법 및 마이크로 소자의 표면 에너지 조절에 의해 제어된 공간적 분포 또는 밀집도로 흡착된 미생물을 포함하는 이동성 마이크로 소자에 관한 것이다. 본 발명에 따르면, 마이크로 소자의 표면 에너지를 조절하여 마이크로 소자에 흡착되는 미생물의 공간적 분포 또는 밀집도를 선택적으로 제어함으로써, 미생물의 운동성에 일관성을 부여하여 체내에서 마이크로 소자를 이동시키는 동력원으로 사용할 수 있게 함과 동시에, 마이크로 소자의 체내 투여를 가능하게 한다. 또한, 미생물 흡착을 위해 마이크로 소자의 표면에 추가적으로 화학적 처리하는 과정을 거치지 않고, 마이크로 소자의 표면 구성 물질이 나타내는 성질만으로 미생물이 선택적으로 흡착시켜 목적하는 이동성을 부여할 수 있다.
Abstract:
PURPOSE: A method for manufacturing a micro device in which microorganisms are selectively adsorbed on the surface is provided to selectively control the spatial distribution or close-packed state of the microorganisms. CONSTITUTION: A method for manufacturing a mobile micro device having microorganisms(120) selectively adsorbed on the surface comprises a step of partially or entirely controlling the surface energy of the micro device to control the spatial distribution or close-packed state of the microorganisms. The surface energy is controlled by varying the physical or chemical properties of the materials forming the micro device.
Abstract:
PURPOSE: A micro-patterned device and a method for compensating distortion of an optical coherent tomography image using the same are provided to be widely used for analyzing the result of experimental data and checking errors. CONSTITUTION: A micro-patterned device comprises a body(210) and micro patterns(200). The body is formed to be inserted into an organism. Micro patterns consist of a plurality of identifying areas(201,202). The identifying areas are formed on the surface of the body. The size of each identifying area is within 10 μm~100 μm. Each identifying area comprises a protrusion or a depression. The device comprises a metallic material on each identifying area and an organism-compatible material coated on the metallic material.