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公开(公告)号:KR101902832B1
公开(公告)日:2018-10-01
申请号:KR1020180062660
申请日:2018-05-31
Applicant: 전남대학교산학협력단
IPC: A61K31/496 , A61P19/08 , A61P19/10
CPC classification number: A61K31/496 , A61P19/08 , A61P19/10
Abstract: 본발명은특정화합물을포함함으로써, 조골세포분화를억제할뿐만아니라파골세포분화또한억제하는효과를가져, 치주염등을포함하는골질환에대한우수한약효및 건강기능성을나타낼수 있는조성물에관한것이다.
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公开(公告)号:KR101861574B1
公开(公告)日:2018-06-29
申请号:KR1020180035416
申请日:2018-03-27
Applicant: 전남대학교산학협력단
CPC classification number: C12N9/88 , C07K1/22 , C12N15/52 , C12N15/70 , C12Y503/04001
Abstract: 본발명은재조합단백질및 이의제조방법에관한것으로서, 보다상세하게는현저히개선된수용성을가져, 용이하게분리, 정제가가능한 PDIA 3 단백질및 이를대량으로발현하고용이하게분리, 정제가가능한제조방법에관한것이다.
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公开(公告)号:KR1020130046457A
公开(公告)日:2013-05-08
申请号:KR1020110110848
申请日:2011-10-28
Applicant: 전남대학교산학협력단
IPC: G01N33/574 , C12Q1/68 , C12N15/11
CPC classification number: C07K7/08 , C07K7/06 , C07K16/18 , C12Q1/6886 , C12Q2600/158 , G01N33/57419 , G01N33/6893 , G01N2033/57465 , C12Q2600/118
Abstract: PURPOSE: A novel marker for diagnosing colon cancer and a kit for diagnosing colon cancer using the same are provided to determine metastasis and prognosis of colon cancer. CONSTITUTION: A polypeptide is denoted by an amino acid sequence selected from the group consisting of sequence numbers 1-4. The polynucleotide encodes the amino acid sequence. A polynucleotide has base sequences of sequence numbers 5-8. A composition for detecting a cancer marker contains a material for detecting the expression of the polypeptide or the polynucleotide. A composition for detecting the cancer marker contains: an antibody which specifically binds to the polypeptide or a combination thereof, or a primer pair which specifically binds to the polynucleotide, a probe, or an antisense nucleotide. A kit for diagnosing cancer contains the composition.
Abstract translation: 目的:提供用于诊断结肠癌的新型标志物和用于诊断结肠癌的试剂盒,以确定结肠癌的转移和预后。 构成:多肽由选自序列号1-4的氨基酸序列表示。 多核苷酸编码氨基酸序列。 多核苷酸具有序列号5-8的碱基序列。 用于检测癌症标志物的组合物含有用于检测多肽或多核苷酸表达的材料。 用于检测癌症标志物的组合物包含:特异性结合多肽或其组合的抗体,或特异性结合多核苷酸,探针或反义核苷酸的引物对。 用于诊断癌症的试剂盒包含组合物。
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公开(公告)号:KR1020100098039A
公开(公告)日:2010-09-06
申请号:KR1020090017002
申请日:2009-02-27
Applicant: 전남대학교산학협력단
Abstract: PURPOSE: An antibody to a specific region of selenoprotein O is provided to use in western blotting and immunoprecipitation and to quantify and qualify selenoprotein O. CONSTITUTION: An isolated peptide comprises an amino acid sequence of sequence number 1. The peptide contains a cystein at N-terminal for KLH conjugation. The peptide is modified by amidation of C-terminal. An antibody which specifically binds to the peptide with an amino acid of sequence number 1 specifically binds to selenoprotein O. The antibody is used in western blotting or ELISA analysis. A method for detecting a specific polypeptide in a sample comprises: a step of contacting the antibody to the sample; a step of forming complex of the specific polypeptide and antibody; and a step of detecting the complex.
Abstract translation: 目的:提供用于蛋白质印迹和免疫沉淀的特定区域的抗体,并对硒蛋白O进行定量和鉴定。构成:分离的肽包含序列号1的氨基酸序列。肽含有N末端的半胱氨酸 - KLH缀合的末端。 肽通过C-末端的酰胺化来修饰。 与序列号1的氨基酸特异性结合肽的抗体特异性结合于硒蛋白O.抗体用于western印迹或ELISA分析。 用于检测样品中特定多肽的方法包括:使抗体与样品接触的步骤; 形成特异性多肽和抗体复合物的步骤; 以及检测复合物的步骤。
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公开(公告)号:KR101948917B1
公开(公告)日:2019-02-15
申请号:KR1020180062661
申请日:2018-05-31
Applicant: 전남대학교산학협력단
IPC: A61K31/501 , A23L33/10 , A61P19/08 , A61P19/10
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公开(公告)号:KR101907908B1
公开(公告)日:2018-10-15
申请号:KR1020180033712
申请日:2018-03-23
Applicant: 전남대학교산학협력단
CPC classification number: A61K38/1709 , A61P1/02 , A61P19/08 , A61P19/10
Abstract: 본발명은특정단백질을포함함으로써, 조골세포분화를억제할뿐만아니라파골세포분화또한억제하는효과를가짐으로써치주염, 골암등을포함하는골질환에대한우수한약효및 건강기능성을나타낼수 있는조성물에관한것이다.
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公开(公告)号:KR101769789B1
公开(公告)日:2017-08-21
申请号:KR1020160070339
申请日:2016-06-07
Applicant: 전남대학교산학협력단
IPC: C12Q1/26 , C12Q1/48 , C07K14/00 , G01N33/574
CPC classification number: C12Q1/26 , C07K14/00 , C12Q1/485 , G01N33/57415
Abstract: 본발명은 NADPH와결합하여형광을띄는메타게놈유래의단백질 mBFP(metagenome-derived blue fluorescent protein)의변이체를활용한 NAD(H) 정량용조성물및 정량방법에관한것으로것으로, 조효소인 NAD(H)와 NADP(H)를모두정량할 수있고, 기존의조효소정량키트에존재하는문제점을해결하였으며, 나아가이를활용하여각종질환의진단과 NAD(H) 또는 NADP(H) 의존적인효소의라이브러리를구축할수 있다.
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公开(公告)号:KR101341732B1
公开(公告)日:2013-12-20
申请号:KR1020110008928
申请日:2011-01-28
Applicant: 전남대학교산학협력단
IPC: C07K14/78 , G01N33/68 , G01N33/574 , C07K16/18
Abstract: 본발명은난소암진단을위한콜라겐유형Ⅵ 알파 1의신규한용도에관한것으로보다상세하게는산화된콜라겐유형Ⅵ 알파 1(collagen type VI alpha 1) 폴리펩티드또는이에대한결합물질, 이를유효성분으로포함하는난소암진단용조성물. 상기조성물을함유한키트, 이를이용한진단방법, 콜라겐유형Ⅵ 알파 1(collagen type VI alpha 1) 폴리펩티드의난소암특이적산화부위에대한다형성폴리펩티드및 이에대한항체에관한것이다. 본발명은난소암을진단할수 있는새로운방법을제공한다. 본발명의콜라겐유형Ⅵ 알파 1 폴리펩티드는난소암에서특이적으로산화변형을보이므로이를검출하는경우난소암의진단의목적으로유용하게사용할수 있다.
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