-
公开(公告)号：KR101334159B1
公开(公告)日：2013-11-27
申请号：KR1020130049461
申请日：2013-05-02
Applicant: 충남대학교산학협력단
Abstract: The present invention relates to a method for screening hepatotoxicity of a drug metabolite using human liver microsome (HLM), comprising steps of: 1) culturing hepatocarcinoma cells and treating hepatocarcinoma cells with a test material and HLM; 2) exchanging a medium and culturing the hepatocarcinoma cells; and confirming cytotoxicity in the hepatocarcinoma cells. [Reference numerals] (AA) Cell survival rate (the rate compared to a control group)
Abstract translation: 本发明涉及使用人肝微粒体（HLM）筛选药物代谢物的肝毒性的方法，包括以下步骤：1）用测试材料和HLM培养肝癌细胞和治疗肝癌细胞; 2）交换培养基并培养肝癌细胞; 并确认肝细胞中的细胞毒性。 （附图标记）（AA）细胞存活率（与对照组相比的速率）
-
-
13.发明授权
公开(公告)号：KR101827794B1
公开(公告)日：2018-02-09
申请号：KR1020160026926
申请日：2016-03-07
Applicant: 충남대학교산학협력단
IPC: C07C275/26 , A61K31/17 , C07C275/30 , C07C273/16
Abstract: 본발명은 1,3-이치환유레아유도체화합물, 이의광학이성질체, 또는이의약학적으로허용가능한염, 및이를유효성분으로포함하는심혈관질환의예방또는치료용약학조성물에관한것으로, 1,3-이치환유레아유도체화합물은 sEH의억제활성이우수하여 EET가 DHET로대사되는과정을효과적으로막을수 있어, 심혈관질환의예방또는치료용약학조성물로유용하게사용될수 있다.
-
14.发明授权
公开(公告)号：KR101035463B1
公开(公告)日：2011-05-18
申请号：KR1020070141245
申请日：2007-12-31
Applicant: 충남대학교산학협력단
IPC: A61K36/258 , A61P31/16
Abstract: 본 발명은 고온고압 제조방법을 이용하여 제조된 흑삼 뿌리로부터 추출된 추출물을 유효성분으로 함유하는 조성물에 관한 것으로, 상세하게는 본 발명의 조성물은 뛰어난 고병원성 조류 인플루엔자 바이러스(highly pathogenic avian influenza)에 대한 억제 효과를 나타내므로, 고병원성 조류 인플루엔자 바이러스 감염증의 예방 및 치료용 약학조성물 및 건강기능식품으로 유용하게 이용될 수 있다.
흑삼, 고병원성 조류 인플루엔자 바이러스-
15.发明公开흑삼 가공 뿌리 추출물을 유효성분으로 함유하는 고병원성 조류 인플루엔자 바이러스의 예방 및 치료용 조성물 有权一种包含PANAX GINSENG加工提取物预防和治疗病原性AVIAN流感病毒的组合物
公开(公告)号：KR1020090073328A
公开(公告)日：2009-07-03
申请号：KR1020070141245
申请日：2007-12-31
Applicant: 충남대학교산학협력단
IPC: A61K36/258 , A61P31/16
Abstract: A composition for preventing and treating highly pathogenic avian influenza virus is provided to have suppression effect to highly pathogenic avian influenza virus by using an extract isolated from Panax ginseng. A method for producing a composition for preventing and treating highly pathogenic avian influenza virus comprises: a step of producing a Panax ginseng; a step of mixing the Panax ginseng with water in a mass ratio of 1:3-7, and maintaining at room temperature for 3-7 hours; a step of adding water containing purified water, low alcohol of C1-4, or their mixture solvent in a mass ratio of 1:5-20; a step of extracting for 2-8 hours one to five times; and a step of cooling, filtering and concentrating the extract.
Abstract translation: 本发明提供了用于预防和治疗高致病性禽流感病毒的组合物，通过使用从人参中分离出的提取物，对高致病性禽流感病毒具有抑制作用。 一种用于预防和治疗高致病性禽流感病毒的组合物的制备方法包括：生产人参的步骤; 将人参与水以1:3-7的质量比混合的步骤，并在室温下保持3-7小时; 以1：5-20的质量比添加含有纯水，C1-4的低级醇或其混合溶剂的水的步骤; 提取2-8小时1-5次; 以及冷却，过滤和浓缩提取物的步骤。
-
Patent Agency Ranking
公开(公告)号：KR102098126B1
公开(公告)日：2020-04-07
申请号：KR1020180154294
申请日：2018-12-04
Applicant: 충남대학교산학협력단
IPC: A61K31/216 , A61P35/00
-
17.发明公开1,3-이치환유레아 유도체 화합물, 이의 광학이성질체, 또는 이의 약학적으로 허용 가능한 염, 및 이를 유효성분으로 포함하는 심혈관 질환의 예방 또는 치료용 약학 조성물 审中-实审一种1,3-二取代脲衍生物化合物，其光学异构体或其药学上可接受的盐，以及用于预防或治疗心血管疾病的药物组合物，其包含其作为活性成分
公开(公告)号：KR1020170104218A
公开(公告)日：2017-09-15
申请号：KR1020160026926
申请日：2016-03-07
Applicant: 충남대학교산학협력단
IPC: C07C275/26 , A61K31/17 , C07C275/30 , C07C273/16
Abstract: 본발명은 1,3-이치환유레아유도체화합물, 이의광학이성질체, 또는이의약학적으로허용가능한염, 및이를유효성분으로포함하는심혈관질환의예방또는치료용약학조성물에관한것으로, 1,3-이치환유레아유도체화합물은 sEH의억제활성이우수하여 EET가 DHET로대사되는과정을효과적으로막을수 있어, 심혈관질환의예방또는치료용약학조성물로유용하게사용될수 있다.
Abstract translation: 本发明涉及1,3-二取代脲衍生物化合物，其光学异构体或其药学上可接受的盐以及用于预防或治疗心血管疾病的药物组合物，其包含其作为活性成分， 尿素衍生物化合物可以通过抑制sEH来有效地抑制EET代谢为DHET的过程，因此可以有效地用作预防或治疗心血管疾病的药物组合物。
-
公开(公告)号：KR101652305B1
公开(公告)日：2016-08-30
申请号：KR1020150016300
申请日：2015-02-02
Applicant: 충남대학교산학협력단
IPC: A61K31/403 , A61K31/17
Abstract: 본발명은카바졸유레아유도체를함유하는혈관질환의예방또는치료용조성물에관한것으로서, 상기카바졸유레아유도체는혈소판응집억제효과와생체내 안정성이매우우수하여혈관질환의예방또는치료용의약조성물로용이하게이용가능하다.
-
公开(公告)号：KR1020150111825A
公开(公告)日：2015-10-06
申请号：KR1020140193610
申请日：2014-12-30
Applicant: 충남대학교산학협력단
IPC: C07D203/16 , A61K31/396 , C07D403/12 , C07D401/12
CPC classification number: C07D203/16 , A61K31/396 , C07D401/12 , C07D403/12
Abstract: 본발명은강심활성을지니는화합물및 이를함유하는약학적조성물을개시하며, 본발명에따른화합물을포함하는조성물은심부전의예방및 치료에유용하다.
Abstract translation: 公开了具有强心活性的化合物和含有该化合物的药物组合物，根据本发明的含有该化合物的组合物可用于预防和治疗心力衰竭。
-
公开(公告)号：KR100987236B1
公开(公告)日：2010-10-12
申请号：KR1020090027695
申请日：2009-03-31
Applicant: 충남대학교산학협력단
Abstract: PURPOSE: A composition comprising dried powder and an extract of epimedium leaves, and a manufacturing method of an animal feed including thereof are provided to secure the generative power reinforcing activity of an antioxidant or the animal feed including the composition. CONSTITUTION: A manufacturing method of an animal feed including a composition comprising dried powder and an extract of epimedium leaves comprises the following steps: cutting the epimedium leaves; adding a mixed solution containing purified water and low class alcohol; and extracting for 1 hour~10 days in 15~30 deg C using an sonication extraction method; condensing and freeze-drying the extract; and mixing with the animal feed in a powder or granule state.
Abstract translation: 目的：提供一种包含干燥粉末和淫羊藿叶提取物的组合物及其包含动物饲料的制造方法，以确保抗氧化剂或包含该组合物的动物饲料的生成力增强活性。 构成：包含干粉和淫羊藿提取物的组合物的动物饲料的制造方法包括以下步骤：切割淫羊藿叶; 加入含有纯净水和低级酒精的混合溶液; 并使用超声处理提取法在15〜30℃下提取1〜10天; 冷凝干燥提取物; 并与粉末或颗粒状态的动物饲料混合。
-
-
-
-
-
-
-
-
-
Search Results
26
records
(took 0.027 seconds)
