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公开(公告)号：KR1020140012580A
公开(公告)日：2014-02-03
申请号：KR1020120147260
申请日：2012-12-17
Applicant: 한국전자통신연구원
Abstract: According to an embodiment of the present invention, an electrode sensor manufacturing method comprises: a step of providing a substrate having a metal thin film; a step of forming a resist layer on the substrate; a step of exposing part of a first electrode by patterning the lift-off resist layer; a step of forming an insulation layer on the substrate; a step of forming a well inside the insulation layer by removing the resist layer and the insulation layer on photoresist; and a step of forming a second electrode which is electrically connected with the first electrode inside the well. The electrode sensor manufacturing method can prevent the damage to the first electrode, and can reduce the impedance of the electrode due to the increasing surface area of the electrode by the second electrode.
Abstract translation: 根据本发明的实施例，电极传感器的制造方法包括：提供具有金属薄膜的基板的步骤; 在衬底上形成抗蚀剂层的步骤; 通过对剥离抗蚀剂层进行构图来暴露第一电极的一部分的步骤; 在基板上形成绝缘层的步骤; 通过去除抗蚀剂层和光致抗蚀剂上的绝缘层在绝缘层内形成阱的步骤; 以及形成与所述阱内的所述第一电极电连接的第二电极的步骤。 电极传感器的制造方法可以防止对第一电极的损伤，并且由于第二电极的电极表面积的增加，可以减小电极的阻抗。
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公开(公告)号：KR1020130063778A
公开(公告)日：2013-06-17
申请号：KR1020110130326
申请日：2011-12-07
Applicant: 한국전자통신연구원
IPC: C07D333/10 , C07D409/04 , C07D409/14 , G01N33/52 , H01B1/12
CPC classification number: C07D333/10 , C07D409/04 , C07D409/14 , G01N33/52 , G01N2333/00 , H01B1/12
Abstract: PURPOSE: A conductive molecular wire is provided to improve signal-to-noise ratio value by surface treatment of an electrode for measuring a neural signal, and to ensure long-term stability by covalent bond with the electrode. CONSTITUTION: A conductive molecular wire has a structure of chemical formula 1. A method for preparing the molecular wire comprises: a step of adding zinc powder(3.8g, 58.0mmol) and dichlorodimethylsilane(7.0mL, 58.0mmol) to 120 ml of a dicholoromethane solution; a step of adding 4-iodobenzenesulfonyl choloride(5.0g, 16.5mmol) and n,n'-dimethylacetamide(4.6mL, 50.0mmol) and reacting at 70 deg. C for 2 hours; a step of adding acetyl chloride(1.53mL, 21.5mmol) and reacting at 50 deg. C for 15 minutes; a step of extracting with water and isolating by column chromatography to obtain a material of chemical formula 2.
Abstract translation: 目的：提供导电分子线，以通过用于测量神经信号的电极的表面处理来提高信噪比值，并通过与电极的共价键来确保长期稳定性。 导电分子线具有化学式1的结构。制备分子线的方法包括：将锌粉（3.8g，58.0mmol）和二氯二甲基硅烷（7.0mL，58.0mmol）加入到120ml的 二氯甲烷溶液; 加入4-碘苯磺酰氯（5.0g，16.5mmol）和n，N'-二甲基乙酰胺（4.6mL，50.0mmol）并在70℃反应的步骤。 C 2小时; 加入乙酰氯（1.53mL，21.5mmol）并在50℃下反应的步骤。 C 15分钟; 用水提取并通过柱色谱法分离以获得化学式2的材料的步骤。
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公开(公告)号：KR1020120055375A
公开(公告)日：2012-05-31
申请号：KR1020100117091
申请日：2010-11-23
Applicant: 한국전자통신연구원
CPC classification number: C12N5/0068 , C12N2533/30 , C12N2537/10
Abstract: PURPOSE: A cell chip and a manufacturing method thereof are provided to simplify manufacturing process by forming patterns by light, control directions of cell growth, and limiting cell growth. CONSTITUTION: A cell chip comprises an immobilization of cell material layer(21) which is arranged on a substrate(10) and photo-crosslinked polymer partition walls(25a) which are arranged on the immobilization of cell material layer. The photo-crosslinked polymer partition walls have bio compatibility. The photo-crosslinked polymer partition walls contain polyfluorene. The immobile of cell material layer contains synthetic polymers having amine radicals within a main chain. The synthetic high polymer is polyethyleneimine. The immobile cell material layer is self-assembled monolayer.
Abstract translation: 目的：提供细胞芯片及其制造方法，以通过光形成图案，控制细胞生长方向和限制细胞生长来简化制造过程。 构成：细胞芯片包括布置在基板（10）上的细胞材料层（21）的固定和光电交联的聚合物分隔壁（25a），其被布置在细胞材料层的固定上。 光交联聚合物分隔壁具有生物相容性。 光交联聚合物分隔壁含有聚芴。 细胞材料层的不动是含有在主链内有胺自由基的合成聚合物。 合成高聚物是聚乙烯亚胺。 固定电池材料层是自组装单层。
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公开(公告)号：KR1020110059249A
公开(公告)日：2011-06-02
申请号：KR1020090115915
申请日：2009-11-27
Applicant: 한국전자통신연구원
Abstract: PURPOSE: A producing method of a fluorescent polymer nanoparticle with the photo-stability is provided to offer hydrophobic fluorescent organic molecules to the nanoparticle. CONSTITUTION: A producing method of a fluorescent polymer nanoparticle with the photo-stability comprises the following steps: dissolving fluorescent organic polymers in a monomer, and obtaining the fluorescent polymer nanoparticle through the emulsion polymerization; surface-processing the surface of the fluorescent polymer nanoparticle using a surfactant; and coating the surface of the fluorescent polymer nanoparticle with silica. The monomer is selected from styrene, methyl methacrylate, methyl acrylate, ethyl acrylate, ethyl methacrylate, vinyl acetate, or acrylic acid.
Abstract translation: 目的：提供具有光稳定性的荧光聚合物纳米颗粒的制备方法，以向纳米颗粒提供疏水荧光有机分子。 构成：具有光稳定性的荧光聚合物纳米颗粒的制造方法包括以下步骤：将荧光有机聚合物溶解在单体中，并通过乳液聚合获得荧光聚合物纳米颗粒; 使用表面活性剂对荧光聚合物纳米颗粒的表面进行表面处理; 并用二氧化硅涂覆荧光聚合物纳米颗粒的表面。 单体选自苯乙烯，甲基丙烯酸甲酯，丙烯酸甲酯，丙烯酸乙酯，甲基丙烯酸乙酯，乙酸乙烯酯或丙烯酸。
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公开(公告)号：KR1020110059114A
公开(公告)日：2011-06-02
申请号：KR1020090115750
申请日：2009-11-27
Applicant: 한국전자통신연구원
IPC: B82B3/00 , B82B1/00 , C01G23/047
CPC classification number: H01L31/1888 , B82Y30/00 , B82Y40/00 , C01G23/04 , C01P2004/64 , H01L31/022466
Abstract: PURPOSE: A producing method of a titanium oxide nanostructure is provided to grow the titanium oxide nanostructure with the excellent electric conductivity on a transparent electrode substrate. CONSTITUTION: A producing method of a titanium oxide nanostructure comprises the following steps: synthesizing a titanium oxide precursor; coating a substrate with the titanium oxide precursor for forming a thin film layer(S150); and etching the thin film layer for producing the titanium oxide nanostructure on the substrate. The titanium oxide precursor is synthesized by a step of dissolving titanium oxide into alcohol before mixing with amine(S110), a step of heating and stirring the mixture while injecting inert gas into the mixture(S120), and a step of secondly stirring and heating the mixture(S130).
Abstract translation: 目的：提供一种氧化钛纳米结构体的制造方法，在透明电极基板上以优异的导电性生长氧化钛纳米结构体。 构成：二氧化钛纳米结构体的制造方法包括以下步骤：合成氧化钛前体; 用氧化钛前体涂覆基材以形成薄膜层（S150）; 并在基板上蚀刻用于制造氧化钛纳米结构的薄膜层。 通过在与胺混合之前将氧化钛溶解在醇中的步骤（S110）合成氧化钛前体，在混合物中注入惰性气体的同时加热搅拌的步骤（S120），第二次搅拌加热 混合物（S130）。
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Patent Agency Ranking
公开(公告)号：KR1020140042353A
公开(公告)日：2014-04-07
申请号：KR1020120109029
申请日：2012-09-28
Applicant: 한국전자통신연구원
Abstract: An electrode array according to an embodiment of the present invention comprises: a first electrode on a substrate; a second electrode arranged on the first electrode, and having the upper side and the lower side opposed to each other; an electrode supporter coming in contact with the second electrode and having an inner surface and an outer surface perpendicular to the substrate; and a third electrode coming in contact with the upper side of the second electrode and the inner surface of the electrode supporter. The electrode array of the present invention has an improved impedance performance, and an improved interface between a biological tissue and the electrode.
Abstract translation: 根据本发明实施例的电极阵列包括：基板上的第一电极; 布置在所述第一电极上并具有彼此相对的上侧和下侧的第二电极; 与第二电极接触并且具有垂直于衬底的内表面和外表面的电极支撑件; 以及与第二电极的上侧和电极支撑体的内表面接触的第三电极。 本发明的电极阵列具有改善的阻抗性能，以及生物组织和电极之间改进的界面。
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公开(公告)号：KR1020130063777A
公开(公告)日：2013-06-17
申请号：KR1020110130324
申请日：2011-12-07
Applicant: 한국전자통신연구원
IPC: A61B5/0478 , G03F7/20 , B82B3/00 , B82Y5/00
CPC classification number: A61B5/0478 , B82B3/009 , B82Y5/00 , G03F7/20
Abstract: PURPOSE: A surface treatment method for a neural electrode array using a zinc oxide nanowire is provided to allow the array to have surface roughness using the nanowire and to form a neuron adhesion material on the nanowire, thereby stably growing a neuron on the front surface of the array. CONSTITUTION: A surface treatment method for a neural electrode array(10) using a zinc oxide nanowire(31) includes the following steps: a step of preparing the array; a step of forming a metal seed layer on the array; a step of etching the metal seed layer; a step of growing the nanowire on the metal seed layer which is not removed in the previous step of etching; and a step of forming a neuron adhesion material(41) on the nanowire.
Abstract translation: 目的：提供使用氧化锌纳米线的神经电极阵列的表面处理方法，以使阵列具有使用纳米线的表面粗糙度，并在纳米线上形成神经元粘附材料，从而稳定地生长在前表面上的神经元 阵列。 构成：使用氧化锌纳米线（31）的神经电极阵列（10）的表面处理方法包括以下步骤：准备阵列的步骤; 在阵列上形成金属种子层的步骤; 蚀刻金属种子层的步骤; 在前面的蚀刻步骤中在金属种子层上生长纳米线的步骤，其不被去除; 以及在纳米线上形成神经元粘附材料（41）的步骤。
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公开(公告)号：KR1020120067087A
公开(公告)日：2012-06-25
申请号：KR1020100128514
申请日：2010-12-15
Applicant: 한국전자통신연구원
IPC: H01L21/027 , A61B5/0408 , B82B3/00
CPC classification number: A61B5/04082 , A61B5/04085 , B82B3/0009 , B82B3/0014 , H01L21/0274
Abstract: PURPOSE: A method of manufacturing a titanium oxide film and a neural electrode including the titanium oxide film manufactured by the method are provided to produce a hierarchy structure where a micro structure and a nano structure simultaneously exist by surface-reforming a titanium oxide pattern to a nanoporous structure with an alkaline hydrothermal reaction. CONSTITUTION: A titanium oxide sol layer is formed by applying titanium oxide sol onto a substrate. A patterned titanium oxide gel layer is formed by heating the titanium oxide sol layer. The titanium oxide film having nano sized pores is formed by letting the patterned titanium oxide gel layer have hydrothermal reaction.
Abstract translation: 目的：提供一种制造氧化钛膜的方法和包括通过该方法制造的氧化钛膜的神经电极，以通过将氧化钛图案表面重整形成为同时存在微结构和纳米结构的层次结构 纳米孔结构与碱性水热反应。 构成：通过将氧化钛溶胶施加到基材上形成氧化钛溶胶层。 通过加热氧化钛溶胶层形成图案化的氧化钛凝胶层。 通过使图案化氧化钛凝胶层具有水热反应形成具有纳米尺寸孔的氧化钛膜。
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公开(公告)号：KR101118223B1
公开(公告)日：2012-03-16
申请号：KR1020090089686
申请日：2009-09-22
Applicant: 한국전자통신연구원
Abstract: 본 발명은 역 구조 기판 식각에 기반한 자기저항 측정 바이오센서 및 그의 제조방법에 관한 것이다. 본 발명의 바이오센서는 유전체층을 먼저 형성한 후 자기저항센서를 형성함으로써, 자기저항센서의 안정성에 손상을 가하지 않고 유전체층을 고온에서 형성할 수 있다. 따라서, 본 발명의 바이오센서는 고품질의 유전체층 박막을 포함하며, 그에 따르는 우수한 측정감도를 갖는다. 또한, 별도의 공정 없이 기판의 식각에 의하여 시료접촉 금속막 상에 시료적용 용기가 형성되므로 시료의 적용이 매우 편리하다.
자기저항센서, 바이오센서, 유전체층, 기판식각-
公开(公告)号：KR101373809B1
公开(公告)日：2014-03-11
申请号：KR1020090115915
申请日：2009-11-27
Applicant: 한국전자통신연구원
Abstract: 본 발명은 광 안정성을 갖는 형광 중합체 나노입자의 제조방법에 관한 것으로, 본 발명에 따른 형광 중합체 나노입자의 제조방법은 단량체 및 형광 유기분자를 용매중에 용해하여 에멀젼 중합을 통해 형광 유기분자가 포함된 형광 중합체 나노입자를 제조하는 단계; 상기 형광 중합체 나노입자 표면을 계면활성제로 처리하는 단계; 및 상기 계면활성제 처리된 형광 중합체 나노입자 표면을 실리카 코팅하는 단계를 포함한다. 이와 같은 방법으로 제조된 형광 중합체 나노입자는 광 탈색이 거의 없고, 소수성 형광 유기분자를 포함할 수 있고, 형광 유기분자의 농도가 높아져도 형광 세기가 줄어들지 않아 바이오 분석에 응용될 수 있다.
형광, 중합체, 실리카
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