METHODS OF MAKING FIBRIN COMPOSITIONS AND ARTICLES
    11.
    发明申请
    METHODS OF MAKING FIBRIN COMPOSITIONS AND ARTICLES 审中-公开
    制备纤维蛋白组合物和制品的方法

    公开(公告)号:WO2018067532A1

    公开(公告)日:2018-04-12

    申请号:PCT/US2017/054892

    申请日:2017-10-03

    Abstract: A method of forming a fibrin hydrogel composition including providing one or more unitary masses of a fibrin hydrogel, dividing at least one of the unitary masses of the fibrin hydrogel into a multiplicity of smaller pieces of the fibrin hydrogel, and recombining at least a portion of the smaller pieces into a cohesive mass. Dividing at least one of the unitary masses of fibrin hydrogel into a multiplicity of smaller pieces may include shearing or cutting the unitary masses to form an aqueous dispersion of the fibrin hydrogel in an aqueous medium. The aqueous dispersion of fibrin hydrogel may be applied to a substrate on a roller or an endless belt, and is optionally overlaid by a scrim. The cohesive mass of fibrin hydrogel, which may be formed by removing at least a portion of the aqueous medium from the aqueous dispersion of the smaller pieces of the fibrin hydrogel, finds uses in wound dressing articles.

    Abstract translation: 一种形成纤维蛋白水凝胶组合物的方法,包括提供一个或多个纤维蛋白水凝胶的单一团块,将纤维蛋白水凝胶的单一团块中的至少一个分成多个纤维蛋白水凝胶的较小片段 并且将至少一部分小块重新组合成粘性物质。 将至少一个单一纤维蛋白水凝胶块分成多个小块可包括剪切或切割整体块以形成纤维蛋白水凝胶在水性介质中的水分散体。 纤维蛋白水凝胶的水分散体可以施加到辊或环形带上的基底上,并且任选地被稀松布覆盖。 可以通过从纤维蛋白水凝胶的较小部分的水分散体中除去至少一部分水性介质而形成的纤维蛋白水凝胶的粘着块可用于伤口敷料制品。

    FLEXIBLE APPLICATOR HANDLE REGION
    16.
    发明申请

    公开(公告)号:WO2020039296A1

    公开(公告)日:2020-02-27

    申请号:PCT/IB2019/056799

    申请日:2019-08-09

    Abstract: An applicator (100) including a hollow body (110), the hollow body including a distal portion (112), a proximal portion (114), an exterior surface (118), an interior surface (116), and an activation region (120), where the hollow body includes at least two longitudinal grooves (122) on at least one of the exterior surface and the interior surface in the activation region of the applicator, and where the hollow body has a first radial groove (124) in the activation region that is on at least one of the exterior surface or the interior surface. The applicator includes a frangible ampoule (160) inside the hollow body, the frangible ampoule configured to contain a solution. The applicator may include a head (140) having an absorbent component (150) capable of absorbing the contents of the frangible ampoule when the ampoule is fractured and can aid in application of the ampoule contents to the desired surface.

    WOUND DRESSING SYSTEM
    17.
    发明申请

    公开(公告)号:WO2020035811A1

    公开(公告)日:2020-02-20

    申请号:PCT/IB2019/056915

    申请日:2019-08-14

    Abstract: A wound dressing system comprising a drape and a hydrogel sealant. The drape comprises a film and an adhesive on a first major surface of the film. The hydrogel comprises at least 30% by weight water, a crosslinked hydrophilic absorbent polymer; and a swelling agent. The hydrogel can create a seal between the drape and a surface (e.g., a patient's skin), making the disclosed systems suitable for negative pressure wound therapy (NPWT) applications.

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