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37 records (took 0.022 seconds)

    11.
    发明专利
    未知

    公开(公告)号：DK1027361T3

    公开(公告)日：2003-08-25

    申请号：DK98956314

    申请日：1998-10-29

    Applicant: ABBOTT LAB

    Inventor： OR YAT SUN ,  GRIESGRABER GEORGE ,  CHU DANIEL T ,  LI LEPING

    IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

    Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II); compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier; a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention; and processes for their preparation.

    12.
    发明专利
    未知

    公开(公告)号：AT239750T

    公开(公告)日：2003-05-15

    申请号：AT98956314

    申请日：1998-10-29

    Applicant: ABBOTT LAB

    Inventor： OR YAT SUN ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU DANIEL T

    IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

    Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II); compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier; a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention; and processes for their preparation.

    COMPUESTOS A BASE DE ERITROMICINA 6-0 SUSTITUIDA Y TECNICA DE PRODUCCION.
    17.
    发明专利
    COMPUESTOS A BASE DE ERITROMICINA 6-0 SUSTITUIDA Y TECNICA DE PRODUCCION. 未知

    公开(公告)号：ES2252784T3

    公开(公告)日：2006-05-16

    申请号：ES97924605

    申请日：1997-05-06

    Applicant: ABBOTT LAB

    Inventor： OR YAT SUN ,  CLARK RICHARD F ,  MA ZHENKUN ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU DANIEL T

    IPC: C07H17/08 ,  A61K31/70

    Abstract: Un compuesto que tiene la fórmula o una sal farmacéuticamente aceptable del mismo, en la que X es =O, Ra es hidroxi; Rb es hidrógeno; Rc es hidrógeno y Rd es hidroxi; Re es metoxi; Rf es hidrógeno; y R se selecciona entre el grupo compuesto por (2) alquilo C2-C10 sustituido con uno o más sustituyentes seleccionados entre el grupo compuesto por (a) halógeno, (b) hidroxi, (c) alcoxi C1-C3, (d) alcoxi C1-C3-alcoxi C1-C3, (e) oxo, (f) -N3, (g) -CHO, (h) O-SO2-(alquilo C1-C6 sustituido), (i) -NR15R16 en la que R15 y R16 se seleccionan entre el grupo compuesto por (i) hidrógeno, (ii) alquilo C1-C12, (iii) alquilo C1-C12 sustituido, (iv) alquenilo C1-C12, (v) alquenilo C1-C12 sustituido, (vi) alquinilo C1-C12, (vii) alquinilo C1-C12 sustituido, (viii) arilo, (ix) cicloalquilo C3-C8, (x) cicloalquilo C3-C8 sustituido, (xi) arilo sustituido, (xii) heterocicloalquilo, (xiii) heterocicloalquilo sustituido, (xiv) alquilo C1-C12 sustituido con arilo, (xv) alquilo C1-C12 sustituido con arilo sustituido,(xvi) alquilo C1-C12 sustituido con heterocicloalquilo, (xvii) alquilo C1-C12 sustituido con sustituido heterocicloalquilo, (xviii) alquilo C1-C12 sustituido con cicloalquilo C3-C8, (xix) alquilo C1-C12 sustituido con cicloalquilo C3-C8 sustituido, (xx) heteroarilo, (xxi) sustituido heteroarilo, (xxii) alquilo C1-C12 sustituido con heteroarilo, y (xxiii) alquilo C1-C12 sustituido con heteroarilo sustituido, o R15 y R16 tomados junto con el átomo al que están unidos forman morfolinilo; (3) alquenilo C4-C10; y (4) alquinilo C3-C10.

    19.
    发明专利
    未知

    公开(公告)号：ES2198766T3

    公开(公告)日：2004-02-01

    申请号：ES98956314

    申请日：1998-10-29

    Applicant: ABBOTT LAB

    Inventor： OR YAT SUN ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU DANIEL T

    IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

    Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II); compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier; a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention; and processes for their preparation.

    20.
    发明专利
    未知

    公开(公告)号：PT1027361E

    公开(公告)日：2003-09-30

    申请号：PT98956314

    申请日：1998-10-29

    Applicant: ABBOTT LAB

    Inventor： OR YAT SUN ,  LI LEPING ,  CHU DANIEL T ,  GRIESGRABER GEORGE

    IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

    Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II); compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier; a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention; and processes for their preparation.

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