公开(公告)号：CA2564020C

公开(公告)日：2009-10-27

申请号：CA2564020

申请日：1997-09-02

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  PLATTNER JACOB J ,  CHU DANIEL T ,  GRIESGRABER GEORGE ,  CLARK RICHARD F ,  MA ZHENKUN

IPC: C07H17/08 ,  A61K31/7048 ,  C07D405/14 ,  C07D407/12

Abstract: Antimicrobial compounds having formula (V) as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.(See formula V)

公开(公告)号：SI1027361T1

公开(公告)日：2004-02-29

申请号：SI9830484

申请日：1998-10-29

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU DANIEL T

IPC: A61K31/70 ,  C07H17/00

公开(公告)号：UY27008A1

公开(公告)日：2003-05-30

申请号：UY27008

申请日：2001-10-31

Applicant: ABBOTT LAB

Inventor： MA ZHENKUN ,  OR YAT SUN ,  CLARK RICHARD E ,  CHU DANIEL T ,  PLATTNER JACOB J ,  GRIESGRABER GEORGE

IPC: C07H17/08 ,  A61K31/7048 ,  A61P31/04

Abstract: Compuestos antimicrobianos de fórmula, así como las sales farmacéuticamente aceptables, los ésteres o profármacos del mismo; composiciones farmacéuticas que abarcan tales compuestos; métodos para el tratamiento de infecciones bacterianas mediante la administración de tales compuestos; y los procesos para la preparación de los compuestos

公开(公告)号：BG104425A

公开(公告)日：2001-01-31

申请号：BG10442500

申请日：2000-05-11

Applicant: ABBOTT LAB

Inventor： OR YAT S ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU DANIEL T

IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula or compositions comprising a therapeutically effective amount of the invention in combination with a pharmaceutically acceptable carrier, a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention; and processes for their preparation. 19 claims

公开(公告)号：CA2307828A1

公开(公告)日：1999-05-06

申请号：CA2307828

申请日：1998-10-29

Applicant: ABBOTT LAB

Inventor： CHU DANIEL T ,  LI LEPING ,  OR YAT SUN ,  GRIESGRABER GEORGE

IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II); compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier; a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention; and processes for their preparation.

公开(公告)号：CA2563965A1

公开(公告)日：1998-03-12

申请号：CA2563965

申请日：1997-09-02

Applicant: ABBOTT LAB

Inventor： GRIESGRABER GEORGE ,  OR YAT SUN ,  MA ZHENKUN ,  CHU DANIEL T ,  PLATTNER JACOB J ,  CLARK RICHARD F

IPC: C07H17/08 ,  A61K31/351 ,  A61K31/7048 ,  A61P31/04 ,  C07D407/12

Abstract: Antimicrobial compounds having formula (II) as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.

公开(公告)号：CA2253330C

公开(公告)日：2006-07-25

申请号：CA2253330

申请日：1997-05-06

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  CHU DANIEL T ,  MA ZHENKUN ,  LI LEPING ,  GRIESGRABER GEORGE ,  CLARK RICHARD F

IPC: C07H17/08 ,  A61K31/70 ,  C07H23/00

Abstract: Antimicrobial compounds having formula (II), (III), (IV), (V), (VI), (VII), (VIII) and (IX); as well as the pharmaceutically acceptable salts, esters and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.

公开(公告)号：DK1007530T3

公开(公告)日：2006-04-03

申请号：DK97924605

申请日：1997-05-06

Applicant: ABBOTT LAB

Inventor： CLARK RICHARD F ,  MA ZHENKUN ,  CHU DANIEL T ,  OR YAT SUN ,  GRIESGRABER GEORGE ,  LI LEPING

IPC: C07H17/08 ,  A61K31/70

公开(公告)号：AT310010T

公开(公告)日：2005-12-15

申请号：AT97924605

申请日：1997-05-06

Applicant: ABBOTT LAB

Inventor： OR YAT SUN ,  CLARK RICHARD F ,  MA ZHENKUN ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU DANIEL T

IPC: C07H17/08 ,  A61K31/70

公开(公告)号：DE69814441T2

公开(公告)日：2004-04-08

申请号：DE69814441

申请日：1998-10-29

Applicant: ABBOTT LAB

Inventor： OR SUN ,  GRIESGRABER GEORGE ,  LI LEPING ,  CHU T

IPC: A61K31/7042 ,  A61K31/7048 ,  A61P31/04 ,  C07H17/08 ,  C07H17/00 ,  A61K31/70

Abstract: Novel 6,11-bridged erythromycin compounds and pharmaceutically acceptable salts and esters thereof having antibacterial activity having formula (I) or (II); compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier; a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically-effective amount of a compound of the invention; and processes for their preparation.