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公开(公告)号：AU2010353724A1
公开(公告)日：2012-12-20
申请号：AU2010353724
申请日：2010-11-19
Applicant: ABBOTT LAB , ABBOTT GMBH & CO KG
Inventor： AKRITOPOULOU-ZANZE IRINI , BRAJE WILFRIED , DJURIC STEVAN W , WILSON NOEL S , TURNER SEAN C , KRUGER ALBERT W , RELO ANA-LUCIA , SHEKHAR SHASHANK , WELCH DENNIE S , ZHAO HONGYU , GANDARILLA JORGE , GASIECKI ALAN F , LI HUANQIU , THOMPSON CHRISTINA M , ZHANG MIN
Abstract: The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[
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公开(公告)号：MX2010014224A
公开(公告)日：2011-01-21
申请号：MX2010014224
申请日：2009-06-18
Applicant: ABBOTT LAB
Inventor： WANG LEI , YU SU , HAIGHT ANTHONY R , FRANCZYK THADDEUS S II , HILL DAVID R , MCLAUGLIN MAUREEN ANN , SHEKHAR SHASHANK , MEI JIANZHANG
IPC: C07D295/155
Abstract: Se describe un proceso para la preparación del promotor de apoptosis N-(4-(4-((2-(4-clorofenil)-5,5-dimetil-1-ciclohex-1-en-1 -il)metil)piperazinil-1-iI)benzoilo)-4-(((1R)-3-(morfolin-4-iI)-1 -((fenil) metil) propil) amino)-3-(trifluorometil)sulfonil)bencens ulfonamida (ABT-263). De la fórmula (I).
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公开(公告)号：NZ596827A
公开(公告)日：2014-01-31
申请号：NZ59682710
申请日：2010-05-20
Applicant: ABBOTT LAB , ABBOTT GMBH & CO KG
Inventor： WELCH DENNIE S , SHEKHAR SHASHANK , AKRITOPOULOU-ZANZE IRINI , BRAJE WILFRIED , RELO ANA-LUCIA , TURNER SEAN C , GANDARILLA JORGE , WILSON NOEL S , GASIECKI ALAN F , ZHANG MIN , DJURIC STEVAN W , ZHAO HONGYU , KRUGER ALBERT W , THOMPSON CHRISTINA M , LI HUANQIU
IPC: C07D487/04 , A61K31/551 , A61K31/553 , A61K31/554 , A61P25/00 , C07D225/00 , C07D491/04 , C07D495/04
Abstract: 596827 Disclosed is a compound of formula (I), such as (3aS,10bS)-8-chloro-2-methyl-1,2,3,3a,4,5-hexahydrobenzo[e]pyrrolo [3,4-c]azepin-6(10bH)-one and (3aS,10bS)-8-chloro-2-methyl-1,2,3,3a,4,5-hexahydrobenzo[e]pyrrolo [3,4-c]azepin-6(10bH)-one, which is useful for treating disorders associated with 5HT receptors. Also disclosed is a process for making such compounds.
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公开(公告)号：HRP20130635T1
公开(公告)日：2013-08-31
申请号：HRP20130635
申请日：2013-07-05
Applicant: ABBOTT LAB
Inventor： FRANCZYK THADDEUS S II , HILL DAVID R , HAIGHT ANTHONY R , MCLAUGLIN MAUREEN ANN , SHEKHAR SHASHANK , YU SU , MEI JIANZHANG , WANG LEI
IPC: C07D295/13 , C07D295/155
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公开(公告)号：SI2307393T1
公开(公告)日：2013-08-30
申请号：SI200930640
申请日：2009-06-18
Applicant: ABBOTT LAB
Inventor： FRANCZYK THADDEUS S II , HILL DAVID R , HAIGHT ANTHONY R , MCLAUGLIN MAUREEN ANN , SHEKHAR SHASHANK , YU SU , MEI JIANZHANG , WANG LEI
IPC: C07D295/00
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Patent Agency Ranking
公开(公告)号：HK1168853A1
公开(公告)日：2013-01-11
申请号：HK12109595
申请日：2012-09-28
Applicant: ABBOTT LAB , ABBOTT GMBH & CO KG
Inventor： WELCH DENNIE S , AKRITOPOULOU-ZANZE IRINI , BRAJE WILFRIED , DJURIC STEVAN W , WILSON NOEL S , TURNER SEAN C , KRUGER ALBERT W , RELO ANA-LUCIA , SHEKHAR SHASHANK , ZHAO HONGYU , GANDARILLA JORGE , GASIECKI ALAN F , LI HUANQIU , THOMPSON CHRISTINA M , ZHANG MIN
IPC: C07D20060101 , A61K20060101 , A61P20060101
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公开(公告)号：MX2011012479A
公开(公告)日：2012-03-06
申请号：MX2011012479
申请日：2010-05-20
Applicant: ABBOTT LAB
Inventor： TURNER SEAN C , GASIECKI ALAN F , AKRITOPOULOU-ZANZE IRINI , BRAJE WILFRIED , ZHANG MIN , DJURIC STEVAN W , GANDARILLA JORGE , SHEKHAR SHASHANK , WILSON NOEL S , RELO ANA-LUCIA , WELCH DENNIE S , KRUGER ALBERT W , ZHAO HONGYU , LI HUANQIU , THOMPSON CHRISTINA M
IPC: C07D487/04 , A61K31/551 , A61K31/553 , A61K31/554 , A61P25/00 , C07D491/04 , C07D495/04
Abstract: La presente solicitud se refiere a derivados de decahidropirroloazepina fusionada a arilo- y heteroarilo, octahidrooxepinopirrol, dióxido de octahidropirrolotiazepina, decahidrociclohepta[c]pirrol, y octahidrociclohepta[cjpirrol de fórmula (I) (ver fórmula (I)) en donde R1, R2, R3, R4, R5, A, Y1, Y2, e Y3 son como se define en la especificación. La presente solicitud también se refiere a composiciones que comprenden tales compuestos, procesos para hacer tales compuestos, y métodos para tratar condiciones de enfermedad utilizando tales compuestos y composiciones y métodos para identificar tales compuestos.
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公开(公告)号：MX2011008458A
公开(公告)日：2011-09-01
申请号：MX2011008458
申请日：2010-02-09
Applicant: ABBOTT LAB
Inventor： YU SU , HAIGHT ANTHONY R , SHEKHAR SHASHANK , CHMURA PRESTON E , KISHORE VIMAL
IPC: A61K31/135
Abstract: Se describen métodos para hacer compuestos que son agonistas o antagonistas de uno o más de los receptores individuales de la familia del receptor S1P.
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公开(公告)号：CA2761961A1
公开(公告)日：2010-11-25
申请号：CA2761961
申请日：2010-05-20
Applicant: ABBOTT LAB , ABBOTT GMBH & CO KG
Inventor： AKRITOPOULOU-ZANZE IRINI , BRAJE WILFRIED , DJURIC STEVAN W , WILSON NOEL S , TURNER SEAN C , KRUGER ALBERT W , RELO ANA-LUCIA , SHEKHAR SHASHANK , WELCH DENNIE S , ZHAO HONGYU , GANDARILLA JORGE , GASIECKI ALAN F , LI HUANQIU , THOMPSON CHRISTINA M , ZHANG MIN
IPC: C07D487/04 , A61K31/551 , A61K31/553 , A61K31/554 , A61P25/00 , C07D491/04 , C07D495/04
Abstract: The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives of formula (I), wherein R1,R2, R3, R4, R5, A, Y1, Y2, and Y3 are as defined in the specification. The present application also relates to compositions comprising such compounds, processes for making such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.
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公开(公告)号：AU2009260044A1
公开(公告)日：2009-12-23
申请号：AU2009260044
申请日：2009-06-18
Applicant: ABBOTT LAB
Inventor： HILL DAVID R , MCLAUGLIN MAUREEN ANN , WANG LEI , SHEKHAR SHASHANK , MEI JIANZHANG , FRANCZYK THADDEUS S II , HAIGHT ANTHONY R , YU SU
IPC: C07D295/155
Abstract: Processes to make compounds, including N-acylsulfonamide apoptosis promoters are disclosed.
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