公开(公告)号：EP0946122A2

公开(公告)日：1999-10-06

申请号：EP97954551.0

申请日：1997-12-04

Applicant: Abbott Laboratories

Inventor： CUNNINGHAM, David, D. ,  HENNING, Timothy, P. ,  SHAIN, Eric, B. ,  YOUNG, Douglas, F. ,  LOWERY, Michael, G. ,  SCHAPIRA, Thomas, G. ,  GRAHAM, Hugh, W. ,  MUETTERTIES, Andrew, J. ,  CHAMBERS, Geoffrey, R. ,  HUGHES, Graham, J. ,  WATKIN, Jared, L. ,  PROKOP, Gary, F. ,  GOLDFARB, Joshua, P.

IPC: A61B5 ,  G01N33

CPC classification number: A61B5/15186 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150664 ,  A61B5/15113 ,  A61B5/15125 ,  A61B5/1519 ,  A61B5/15194 ,  A61B5/157 ,  A61B5/411 ,  A61B2562/0295

Abstract: Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: (a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and (b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises: (a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump. Preferably, the apparatus also includes a housing. In a further aspect of the invention, a pneumatic lancing assembly is provided. The pneumatic lancing assembly uses differential gas pressure to thrust a lancet into skin tissue. In another aspect of this invention, an article is provided for an article capable of both collecting blood and detecting an analyte in that blood. The article, which contains an appropriate detection element for determining the amount of analyte in the blood, can be used in conjunction with a meter that measures the signal generated by the detection element of the article.

公开(公告)号：EP0783694A1

公开(公告)日：1997-07-16

申请号：EP95936210.0

申请日：1995-09-29

Applicant: Abbott Laboratories

Inventor： HANSMANN, Douglas, D. ,  GRACE, John, P. ,  LOWERY, Michael, G. ,  OOSTA, Gary, M. ,  LOOMIS, Neil, W. ,  SHAIN, Eric, B. ,  SCHAPIRA, Thomas, G.

IPC: G01N33 ,  B01L3 ,  C08G18 ,  C12Q1 ,  G01N37

CPC classification number: G01N33/5304 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2200/10 ,  B01L2300/0636 ,  B01L2300/0825 ,  B01L2400/0406 ,  B01L2400/086 ,  C08G18/0866 ,  C08G18/10 ,  G01N33/54366 ,  G01N33/54393 ,  Y10S435/81 ,  Y10S436/804 ,  Y10S436/805 ,  Y10S436/809 ,  Y10S436/81

Abstract: The present invention relates to analytical devices for determining the presence or amount of an analyte in a test sample. The analytical devices comprise an inlet port, a vent, a channel, and an array of structures. The structures have immobilized reagent covalently or non-covalently attached to the surface of the structures. The immobilized reagent captures analyte in the test sample where it is detected by a detection system. The present invention also provides methods and reagents for performing assays utilizing the analytical devices of the present invention. The present invention also provides methods of manufacturing the analytical devices of the present invention.

公开(公告)号：EP0946122B1

公开(公告)日：2005-06-08

申请号：EP97954551.4

申请日：1997-12-04

Applicant: Abbott Laboratories

Inventor： CUNNINGHAM, David, D. ,  HENNING, Timothy, P. ,  SHAIN, Eric, B. ,  YOUNG, Douglas, F. ,  LOWERY, Michael, G. ,  SCHAPIRA, Thomas, G. ,  GRAHAM, Hugh, W. ,  MUETTERTIES, Andrew, J. ,  CHAMBERS, Geoffrey, R. ,  HUGHES, Graham, J. ,  WATKIN, Jared, L. ,  PROKOP, Gary, F. ,  GOLDFARB, Joshua, P.

IPC: A61B5/15

CPC classification number: A61B5/15186 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150664 ,  A61B5/15113 ,  A61B5/15125 ,  A61B5/1519 ,  A61B5/15194 ,  A61B5/157 ,  A61B5/411 ,  A61B2562/0295

公开(公告)号：EP0959765A1

公开(公告)日：1999-12-01

申请号：EP97906739.0

申请日：1997-02-25

Applicant: Abbott Laboratories

Inventor： OOSTA, Gary, M. ,  ELSTROM, Tuan, A. ,  SHAIN, Eric, B. ,  SCHAPIRA, Thomas, G.

IPC: A61B5 ,  G01N21

CPC classification number: A61B5/1495 ,  A61B5/0059 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/442 ,  A61B5/443

Abstract: A process of calibrating an individual in preparation for the non-invasive measurement of a biological compound across the skin of that individual using non-ionizing radiation is provided. The process includes determining the contribution of one or more skin parameters to the absorption and transmittance data and correcting the subsequent non-invasive measurement of the biological compound for the contribution of the parameter(s).

公开(公告)号：EP0664000A1

公开(公告)日：1995-07-26

申请号：EP93921623.0

申请日：1993-09-16

Applicant: ABBOTT LABORATORIES

Inventor： FORNEY, Kevin, J. ,  GEIST, Jill, M. ,  LOOMIS, Neil, W. ,  MORICI, Laura, S. ,  MUETTERTIES, Andrew, J. ,  PARSONS, Robert, G. ,  PUTMAN, Jill, M. ,  ROPELLA, Paul, J. ,  SCHAPIRA, Thomas, G. ,  SIEGEL, Neal, A. ,  WAGNER, Brian, K. ,  BASORE, Bob, O.

IPC: G01N33 ,  B01L3

CPC classification number: B01L3/502707 ,  B01L3/5023 ,  B01L3/50273 ,  B01L2200/16 ,  B01L2300/069 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N33/54366 ,  G01N33/54386

Abstract: The present invention is directed to improving the performance of assays using a disposable assay device which includes a porous material in liquid communication with a capillary track. In particular, the capillary track is used in conjunction with the solid support to direct test sample and assay reagents directly to a defined reaction site on or in the porous material. Signal development at the reaction site indicates the assay result. The present invention is also directed to the construction of a disposable assay device which includes a capillary track. In particular, the cappillary track is formed by printing a fluid insoluble material, in the reverse image of the desired capillary track, on a film layer and then capping the printed material. Alternatively, the capillary track is formed by printing a fluid insoluble material, in the reverse image of the desired capillary track, on a porous material which is then sandwiched between two film layers.