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公开(公告)号:CA2409828C
公开(公告)日:2010-08-03
申请号:CA2409828
申请日:2001-05-29
Applicant: BASF AG
Inventor: ROSENBERG JORG , BREITENBACH JORG , HERR DIETER , LAUX VOLKER , HEGER ROBERT
IPC: A61K9/16 , A61K47/12 , A61K9/48 , A61K31/726 , A61K31/727 , A61K47/14 , A61K47/30 , A61K47/32 , A61K47/34 , A61K47/38 , A61K47/44 , A61P1/04 , A61P7/02 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P13/12 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P37/06
Abstract: The invention relates to formulations based on at least one heparin, one glycosaminoglycan or on one heparinoid, and to a formulation base with a lipid constituent and a polymer constituent. The invention also relates to the use of this formulation as a medicament for orally administering at least one heparin, one glycosaminoglycan or one heparinoid, and to a method for preparing the formulations by mixing the formulation constituents while forming a plastic mixture and, optionally, while preparing the formulations as a medicament while, advantageously, using melt extrusion. The lipid constituent advantageously comprises active substance-promoting properties, whereas the polymer constituent is soluble or is capable of swelling. The invention provides that at least portions of the lipid constituent are embedded in a polymer matrix, preferably in molecularly dispersed form. The formulations can form emulsions in water or in aqueous fluids.
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公开(公告)号:NO20025759L
公开(公告)日:2003-01-14
申请号:NO20025759
申请日:2002-11-29
Applicant: BASF AG
Inventor: ROSENBERG JOERG , BREITENBACH JOERG , HERR DIETER , LAUX VOLKER , HEGER ROBERT
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公开(公告)号:NO20025759D0
公开(公告)日:2002-11-29
申请号:NO20025759
申请日:2002-11-29
Applicant: BASF AG
Inventor: ROSENBERG JOERG , BREITENBACH JOERG , HERR DIETER , LAUX VOLKER , HEGER ROBERT
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公开(公告)号:DE10026699A1
公开(公告)日:2001-12-06
申请号:DE10026699
申请日:2000-05-30
Applicant: BASF AG
Inventor: ROSENBERG JOERG , BREITENBACH JOERG , HERR DIETER , LAUX VOLKER , HEGER ROBERT
IPC: A61K47/12 , A61K9/16 , A61K31/726 , A61K31/727 , A61K47/14 , A61K47/30 , A61K47/32 , A61K47/34 , A61K47/38 , A61K47/44 , A61P1/04 , A61P7/02 , A61P9/00 , A61P9/06 , A61P9/10 , A61P11/00 , A61P13/12 , A61P19/02 , A61P27/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P37/06
Abstract: The invention relates to formulations based on at least one heparin, one glycosaminoglycan or on one heparinoid, and to a formulation base with a lipid constituent and a polymer constituent. The invention also relates to the use of this formulation as a medicament for orally administering at least one heparin, one glycosaminoglycan or one heparinoid, and to a method for preparing the formulations by mixing the formulation constituents while forming a plastic mixture and, optionally, while preparing the formulations as a medicament while, advantageously, using melt extrusion. The lipid constituent advantageously comprises active substance-promoting properties, whereas the polymer constituent is soluble or is capable of swelling. The invention provides that at least portions of the lipid constituent are embedded in a polymer matrix, preferably in molecularly dispersed form. The formulations can form emulsions in water or in aqueous fluids.
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公开(公告)号:AU3122189A
公开(公告)日:1989-09-14
申请号:AU3122189
申请日:1989-03-10
Applicant: BASF AG
Inventor: DAUM LOTHAR , SCHLICK ERICH , HERR DIETER , GEISS KARL-HEINZ , DOERPER THOMAS
IPC: C12N9/99 , A61K31/505 , A61K31/52 , A61K31/715 , A61K38/00 , A61K38/19 , A61K38/21 , A61K39/395 , A61K45/06 , A61P31/12 , A61P37/00 , A61P43/00 , A61K31/725
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公开(公告)号:AU2749288A
公开(公告)日:1989-06-29
申请号:AU2749288
申请日:1988-12-23
Applicant: BASF AG
Inventor: HERR DIETER , DOERPER THOMAS , DAUM LOTHAR , GEISS KARL-HEINZ , MOELLER ACHIM
IPC: C08B37/10 , A61K20060101 , A61K31/715 , A61P31/12 , A61K31/725
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