公开(公告)号：CA2151953A1

公开(公告)日：1994-06-23

申请号：CA2151953

申请日：1993-12-04

Applicant: BASF AG

Inventor： HAUPT ANDREAS ,  JANSSEN BERND ,  RITTER KURT ,  KLINGE DAGMAR ,  KEILHAUER GERHARD ,  ROMERDAHL CYNTHIA ,  BARLOZZARI TERESA ,  QIAN XIAO-DONG

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K1/00 ,  C07K5/02 ,  C07K5/027 ,  C07K7/02 ,  C07K7/06 ,  A61K31/425 ,  A61K38/04 ,  C07D277/56 ,  C07D417/12

Abstract: Novel peptides of folmula (I) in which R1, R2, X, A, R3, B, D, E, R7, M, Q, a, b and d have the meanings statod in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.

公开(公告)号：CA1326037C

公开(公告)日：1994-01-11

申请号：CA596231

申请日：1989-04-10

Applicant: BASF AG

Inventor： DAUM LOTHAR ,  KEILHAUER GERHARD ,  LORENZ GISELA ,  AMMERMANN EBERHARD ,  ANKE TIMM ,  WEBER WOLFGANG ,  STEGLICH WOLFGANG ,  STEFFAN BERT ,  SCHERER ANGELA

IPC: C12P17/18 ,  A01N43/90 ,  A61K31/335 ,  A61P31/04 ,  A61P31/12 ,  A61P35/00 ,  C07D493/10 ,  C12R1/645

Abstract: Novel strobilurine derivatives which are suitable for the treatment of disorders and as fungicides are described.

公开(公告)号：ZA8903310B

公开(公告)日：1991-01-30

申请号：ZA8903310

申请日：1989-05-05

Applicant: BASF AG

Inventor： DAUM LOTHAR ,  LOTHAR DAUM ,  KEILHAUER GERHARD ,  GERHARD KEILHAUER ,  LORENZ GISELA ,  GISELA LORENZ ,  ANKE TIMM ,  TIMM ANKE ,  AMMERMANN EBERHARD ,  EBERHARD AMMERMANN ,  WEBER WOLFGANG ,  WOLFGANG WEBER ,  STEGLICH WOLFGANG ,  WOLFGANG STEGLICH ,  STEFFAN BERT ,  BERT STEFFAN ,  SCHERER ANGELA ,  ANGELA SCHERER

IPC: C12P17/18 ,  A01N43/90 ,  A61K31/335 ,  A61P31/04 ,  A61P31/12 ,  A61P35/00 ,  C07D493/10 ,  C12R1/645 ,  C07D ,  A01N ,  A61K ,  C12P

CPC classification number: C07D493/10

公开(公告)号：ZA883428B

公开(公告)日：1990-01-31

申请号：ZA883428

申请日：1988-05-16

Applicant: BASF AG

Inventor： DOERPER THOMAS ,  THOMAS DOERPER ,  MOELLER ACHIM ,  ACHIM MOELLER ,  HILLEN HEINZ ,  HEINZ HILLEN ,  KEILHAUER GERHARD ,  GERHARD KEILHAUER ,  EMLING FRANZ ,  FRANZ EMLING ,  DAUM LOTHAR ,  LOTHAR DAUM

IPC: A61K38/00 ,  A61P35/00 ,  C07K1/20 ,  C12N15/09 ,  C07K14/00 ,  C07K14/52 ,  C07K14/525 ,  C07K14/78 ,  C07K19/00 ,  C12P21/02 ,  C12R1/19 ,  C07K ,  C07H ,  C12P

Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.

公开(公告)号：AU590861B2

公开(公告)日：1989-11-16

申请号：AU7452187

申请日：1987-06-19

Applicant: BASF AG

Inventor： SCHOLLMEIER KLAUS ,  MOELLER ACHIM ,  KOERWER WOLFGANG ,  DOERPER THOMAS ,  HILLEN HEINZ ,  DAUM LOTHAR ,  EMLING FRANZ ,  KEILHAUER GERHARD

IPC: C07K14/52 ,  A61K38/00 ,  A61P35/00 ,  C07K14/00 ,  C07K14/525 ,  C12N15/00 ,  C12N15/09 ,  C12P21/02 ,  C12R1/19 ,  C07K13/00 ,  A61K37/02 ,  A61K37/42 ,  C07G17/00 ,  C07H21/04 ,  C12N1/20 ,  C12P19/34

公开(公告)号：DK263588A

公开(公告)日：1988-11-17

申请号：DK263588

申请日：1988-05-13

Applicant: BASF AG

Inventor： DOERPER THOMAS ,  MOELLER ACHIM ,  HILLEN HEINZ ,  KEILHAUER GERHARD ,  EMLING FRANZ ,  DAUM LOTHAR

IPC: C12N15/09 ,  A61K38/00 ,  A61P35/00 ,  C07K1/20 ,  C07K14/00 ,  C07K14/52 ,  C07K14/525 ,  C07K14/78 ,  C07K19/00 ,  C12P21/02 ,  C12R1/19 ,  C07K13/00 ,  C12N15/00

Abstract: Tumor necrosis factor (TNF) produced from the TNF molecule by modification at the amino terminus are prepared as described and are suitable for controlling diseases.

公开(公告)号：AU7999687A

公开(公告)日：1988-04-28

申请号：AU7999687

申请日：1987-10-21

Applicant: BASF AG

Inventor： SEITZ WERNER ,  DAUM LOTHAR ,  EMLING FRANZ ,  KEILHAUER GERHARD

IPC: A61K31/275 ,  A61K31/277 ,  A61P35/00

公开(公告)号：FI872635A

公开(公告)日：1987-12-21

申请号：FI872635

申请日：1987-06-12

Applicant: BASF AG

Inventor： SCHOLLMEIER KLAUS ,  MOELLER ACHIM ,  KOERWER WOLFGANG ,  DOERPER THOMAS ,  HILLEN HEINZ ,  DAUM LOTHAR ,  EMLING FRANZ ,  KEILHAUER GERHARD

IPC: C07K14/52 ,  A61K38/00 ,  A61P35/00 ,  C07K14/00 ,  C07K14/525 ,  C12N15/00 ,  C12N15/09 ,  C12P21/02 ,  C12R1/19 ,  C12N

公开(公告)号：FI872635A0

公开(公告)日：1987-06-12

申请号：FI872635

申请日：1987-06-12

Applicant: BASF AG

Inventor： SCHOLLMEIER KLAUS ,  MOELLER ACHIM ,  KOERWER WOLFGANG ,  DOERPER THOMAS ,  HILLEN HEINZ ,  DAUM LOTHAR ,  EMLING FRANZ ,  KEILHAUER GERHARD

IPC: C07K14/52 ,  A61K38/00 ,  A61P35/00 ,  C07K14/00 ,  C07K14/525 ,  C12N15/00 ,  C12N15/09 ,  C12P21/02 ,  C12R1/19 ,  C12N

公开(公告)号：HU219232B

公开(公告)日：2001-03-28

申请号：HU9600360

申请日：1994-08-08

Applicant: BASF AG

Inventor： BOUSQUET PETER ,  CASTELLANO BERLANGA JOSE MARIA ,  FERNANDEZ BRANA MIGUEL ,  KEILHAUER GERHARD ,  MORAN MOSET MARINA ,  PEREZ DE VEGA MARIA JESUS ,  QIAN XIAO-DONG ,  ROMERDAHL CYNTHIA

IPC: A61K31/47 ,  A61K31/473 ,  A61P35/00 ,  C07D221/14

Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.