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公开(公告)号:CA2686964A1
公开(公告)日:2008-12-11
申请号:CA2686964
申请日:2008-06-03
Applicant: BASF AG
Inventor: GEBERT SILKE , SCHONHERR MICHAEL , MEYER-BOEHM KATHRIN , KOLTER KARL , MASCHKE ANGELIKA
Abstract: The invention relates to a pharmaceutical formulation in the form of aggl omerates containing A) an adjuvant consisting of a) 60 - 97 % by weight of s ugar or sugar alcohols, b) 1 - 25 % by weight of a disintegration agent c)1 - 15 % by weight of water insoluble, film-forming polymers d) 0 -15 % by wei ght of water soluble polymers, and e) 0 - 15 % by weight of additional conve ntional pharmaceutical adjuvants, the sum of the components a) to e) totalli ng 100 % by weight, and B) at least one active ingredient.
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公开(公告)号:DE502006000273D1
公开(公告)日:2008-02-21
申请号:DE502006000273
申请日:2006-04-03
Applicant: BASF AG
Inventor: KOLTER KARL , ASCHERL HERMANN , FUSSNEGGER BERNHARD
IPC: A61K9/20 , C08F226/06 , C08F6/12
Abstract: Purify-hasty, powdered bonding agents comprises a vinyllactampolymer, where the bonding agents exhibits an average particle size of upto 35 mu m and a bulk density of smaller than 0.2 g/ml. Independent claims are included for: (1) use of the bonding agent for production of tablets with high firmness; and (2) the preparation of the bonding agents.
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公开(公告)号:CA2611083A1
公开(公告)日:2006-12-14
申请号:CA2611083
申请日:2006-05-31
Applicant: BASF AG
Inventor: KOLTER KARL , SCHOENHERR MICHAEL , ASCHERL HERMANN
IPC: A61K9/14 , A23L33/15 , A61K9/16 , A61K9/26 , A61K9/48 , A61K31/07 , A61K31/405 , A61K31/4174 , A61K31/426 , A61K31/495 , A61K31/496 , A61K31/5415 , A61K31/55
Abstract: A process for producing solid solutions in powder or granule form of slightly soluble substances in which the slightly soluble substance is in the form of a molecular dispersion in an excipient matrix, by atomizing a solution of the active ingredient and of the matrix excipients, which comprises heating an aqueous suspension of the slightly soluble substance in the presence of the matrix excipients to temperatures above the boiling point under atmospheric pressure, and dissolving the slightly soluble substance, and subsequently converting the solution of the slightly soluble substance and of the matrix excipients by atomizing and drying into a solid form, where the temperature of the spray solution before feeding into the atomizing apparatus is 90° C. to 350° C.
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公开(公告)号:CA2569321A1
公开(公告)日:2006-01-12
申请号:CA2569321
申请日:2005-06-22
Applicant: BASF AG
Inventor: KOLTER KARL , ANGEL MAXIMILIAN , HABICH ANDREAS
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公开(公告)号:CA2548564A1
公开(公告)日:2005-06-23
申请号:CA2548564
申请日:2004-12-09
Applicant: BASF AG
Inventor: KOLTER KARL , KRAEMER KLAUS , WOOLF HERBERT DENNIS
Abstract: The invention relates to a method for treating the surface of food products by applying a polymer film, wherein a polyvinyl alcohol-polyether graft copolym er in the form of an aqueous dispersion is applied on the food product as the film-forming polymer.
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公开(公告)号:ES2223698T3
公开(公告)日:2005-03-01
申请号:ES01123521
申请日:2001-09-29
Applicant: BASF AG
Inventor: ANGEL MAXIMILIAN , SANNER AXEL , KOLTER KARL
IPC: A61K47/32 , A61K9/20 , A61K9/28 , A61K9/32 , C08F216/06 , C08F218/04 , C08F220/28 , C08F261/04
Abstract: Copolímeros hidrosolubles o dispersables en agua obtenibles mediante polimerización iniciada a través de radicales de a) un 80 a un 20 % en peso de (met) acrilato de hidroxi alquilo con 1 a 6 átomos de carbono, así como, en caso dado, uno o varios compuestos de la fórmula (A) o (B) con R1 = H, alquilo con 1 a 6 átomos de carbono, R2 = H, CH3 R3 = alquilo con 1 a 24 átomos de carbono o mezclas de los mismos, en presencia de b) un 20 a un 80 % en peso de alcohol polivinílico (PVA) y c) en caso dado un 0 a un 20 % en peso de otros compuestos polimerizables (C).
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公开(公告)号:SI1195394T1
公开(公告)日:2004-10-31
申请号:SI200130163
申请日:2001-09-29
Applicant: BASF AG
Inventor: ANGEL MAXIMILIAN , SANNER AXEL , KOLTER KARL
IPC: A61K47/32 , A61K9/20 , A61K9/28 , A61K9/32 , C08F216/06 , C08F218/04 , C08F220/28 , C08F261/04
Abstract: The present invention relates to water-soluble or water-dispersible copolymers obtainable by free-radical polymerization of a) 80 to 20% by weight of hydroxy-C 1 -C 6 -alkyl (meth)acrylate and, where appropriate, one or more compounds of the formula (A) or (B) with R 1 =H, C 1 -C 6 -alkyl, R 2 =H, CH 3 R 3 =C 1 -C 24 -alkyl or mixtures thereof in the presence of b) 20 to 80% by weight of polyvinyl alcohol (PVA) and c) where appropriate 0 to 20% by weight of other polymerizable compounds (C), a process for their preparation, and their use as coating agent, binder and/or film-forming excipient in pharmaceutical dosage forms.
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公开(公告)号:DE50103196D1
公开(公告)日:2004-09-16
申请号:DE50103196
申请日:2001-09-29
Applicant: BASF AG
Inventor: ANGEL MAXIMILIAN , SANNER AXEL , KOLTER KARL
IPC: A61K47/32 , A61K9/20 , A61K9/28 , A61K9/32 , C08F216/06 , C08F218/04 , C08F220/28 , C08F261/04
Abstract: The present invention relates to water-soluble or water-dispersible copolymers obtainable by free-radical polymerization of a) 80 to 20% by weight of hydroxy-C 1 -C 6 -alkyl (meth)acrylate and, where appropriate, one or more compounds of the formula (A) or (B) with R 1 =H, C 1 -C 6 -alkyl, R 2 =H, CH 3 R 3 =C 1 -C 24 -alkyl or mixtures thereof in the presence of b) 20 to 80% by weight of polyvinyl alcohol (PVA) and c) where appropriate 0 to 20% by weight of other polymerizable compounds (C), a process for their preparation, and their use as coating agent, binder and/or film-forming excipient in pharmaceutical dosage forms.
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公开(公告)号:ES2212633T3
公开(公告)日:2004-07-16
申请号:ES99948859
申请日:1999-09-24
Applicant: BASF AG
Inventor: GOTSCHE MICHAEL , KOLTER KARL , SANNER AXEL , ANGEL MAXIMILIAN , LEINENBACH ALFRED
IPC: A61K9/32 , A61K9/20 , A61K9/28 , A61K9/70 , A61K31/138 , A61K47/34 , A61P9/12 , C08F2/44 , C08F218/08 , C08F283/06 , C08L71/02
Abstract: The use of polymers which are obtainable by polymerization ofa) at least one vinyl ester of aliphatic C1-C24-carboxylic acids in the presence ofb) polyethers of the general formula I, in which the variables have, independently of one another, the meanings mentioned in the description, as coating agent, binder and/or film-forming excipient in pharmaceutical presentations.
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公开(公告)号:PT1102533E
公开(公告)日:2004-04-30
申请号:PT99939411
申请日:1999-07-28
Applicant: BASF AG
Inventor: BAYER HERBERT , STADLER REINHOLD , SCHNEIDER KARL-HEINRICH , SAUR REINHOLD , KOBER REINER , SEUFERT MICHAEL , KOLTER KARL
IPC: A01N25/12 , A01N25/08 , A01N25/26 , A01N37/18 , A01N37/34 , A01N37/40 , A01N37/50 , A01N37/52 , A01N43/653 , A01N43/82 , A01N43/828 , A01N43/84 , A01N47/24 , A01N47/38
Abstract: The present invention relates to soil-applied CR granules obtainable by applying an active-ingredient-comprising coating to a solid carrier in a fluidized bed, to a process for the preparation of these soil-applied granules, and to a method for controlling phytopathogenic fungi, undesired vegetation, undesired attack by insects and/or for regulating the growth of plants using the soil-applied CR granules according to the invention.
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