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公开(公告)号：SI9300661A
公开(公告)日：1994-06-30
申请号：SI9300661
申请日：1993-12-16
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：CA2151953A1
公开(公告)日：1994-06-23
申请号：CA2151953
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
IPC: A61K38/00 , A61K38/08 , A61P35/00 , C07K1/00 , C07K5/02 , C07K5/027 , C07K7/02 , C07K7/06 , A61K31/425 , A61K38/04 , C07D277/56 , C07D417/12
Abstract: Novel peptides of folmula (I) in which R1, R2, X, A, R3, B, D, E, R7, M, Q, a, b and d have the meanings statod in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：HRP931504B1
公开(公告)日：2001-04-30
申请号：HRP931504
申请日：1993-12-16
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QUIAN XIAO-DONG
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公开(公告)号：DK0691962T3
公开(公告)日：2000-10-16
申请号：DK94911931
申请日：1994-03-19
Applicant: BASF AG
Inventor： JANSSEN BERND , KLING ANDREAS , MUELLER STEFAN , RITTER KURT , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , TRAUGOTT ULRICH , SCHLECKER RAINER
IPC: C07D295/08 , A61K31/34 , A61K31/341 , A61K31/357 , A61K31/36 , A61K31/40 , A61K31/403 , A61K31/41 , A61K31/42 , A61K31/421 , A61K31/4245 , A61K31/425 , A61K31/426 , A61K31/433 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4409 , A61K31/4412 , A61K31/4418 , A61K31/445 , A61K31/451 , A61K31/47 , A61K31/495 , A61K31/496 , A61P35/00 , C07D207/32 , C07D207/333 , C07D209/52 , C07D211/14 , C07D213/30 , C07D215/14 , C07D261/08 , C07D261/18 , C07D263/14 , C07D263/32 , C07D271/06 , C07D271/10 , C07D277/24 , C07D285/12 , C07D295/092 , C07D307/42 , C07D307/58 , C07D317/58 , C07D317/66 , C07D333/06 , C07D333/16 , C07D413/12 , C07D417/12 , C07D521/00 , C07F9/6509
Abstract: This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula 1: 1 (in which A, B, R, Rx, X and Z are defined as in the specification described) and methods for their preparation. These compounds may be used as modulators of multidrug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.
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公开(公告)号：CZ286752B6
公开(公告)日：2000-06-14
申请号：CZ157595
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
IPC: A61K38/00 , A61K38/08 , A61P35/00 , C07K1/00 , C07K5/02 , C07K5/027 , C07K7/02 , C07K7/06 , A61K38/07
Abstract: In the present invention there are disclosed peptides of the general formula I, in which the substituents and variables have specific meanings, further pharmaceutical preparation in which the peptides are comprised. These substances can be used for treating neoplastic diseases.
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Patent Agency Ranking
公开(公告)号：DE69320339T2
公开(公告)日：1998-12-17
申请号：DE69320339
申请日：1993-05-10
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , A61K38/04
Abstract: Novel derivates of dolastatin of formula (I) in which R , R , A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：ES2118955T3
公开(公告)日：1998-10-01
申请号：ES93909931
申请日：1993-05-10
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , A61K38/04
Abstract: Novel derivates of dolastatin of formula (I) in which R , R , A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：NO975711L
公开(公告)日：1998-01-30
申请号：NO975711
申请日：1997-12-05
Applicant: BASF AG
Inventor： HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
Abstract: Novel compounds of the formulaR1R2N-CHX-CO-A-B-D-(E)s-(F)t-(G)U-KIin which R1, R2, A, B, D, E, F, G, K, X, s, t, and u have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号：NZ258882A
公开(公告)日：1997-06-24
申请号：NZ25888293
申请日：1993-12-04
Applicant: BASF AG
Inventor： HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号：HUT73529A
公开(公告)日：1996-08-28
申请号：HU9600360
申请日：1994-08-08
Applicant: BASF AG
Inventor： BOUSQUET PETER , CASTELLANO BERLANGA JOSE MARIA , FERNANDEZ BRANA MIGUEL , KEILHAUER GERHARD , MORAN MOSET MARINA , PEREZ DE VEGA MARIA JESUS , QIAN XIAO-DONG , ROMERDAHL CYNTHIA
IPC: A61K31/47 , A61K31/473 , A61P35/00 , C07D221/14 , A61K31/435
Abstract: Disclosed herein are compounds pharmaceutical compositions containing same of the formula 1. A compound of the Formula wherein X, X', X'' and X''', A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
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