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公开(公告)号:NO147877C
公开(公告)日:1983-06-29
申请号:NO794316
申请日:1979-12-28
Applicant: BASF AG
Inventor: TREIBER HANS JOERG , LENKE DIETER , WORSTMANN WOLFGANG
IPC: A61K31/55 , A61K31/553 , A61P25/04 , C07D267/10
Abstract: Novel hexahydro-1,4-oxazepines of the general formula I I where R1 is hydrogen, or alkyl or acyl each of 1 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and R3 and R4 are identical or different and each is hydrogen or methyl, and their salts with physiologically acceptable acids, processes for their preparation, drugs which contain these compounds, and their use in therapy. The compounds may be used for the pharmacotherapy of pain of various geneses.
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公开(公告)号:FI801228A
公开(公告)日:1980-11-11
申请号:FI801228
申请日:1980-04-17
Applicant: BASF AG
Inventor: STEINER GERD , FRANKE ALBRECHT , LENKE DIETER , TESCHENDORF HANS-JUERGEN , WORSTMANN WOLFGANG , KREISKOTT HORST
IPC: A61K31/55 , A61P25/18 , C07D223/20 , C07D401/06 , C07D403/04 , C07D
Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.
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公开(公告)号:FI71132C
公开(公告)日:1986-11-24
申请号:FI801228
申请日:1980-04-17
Applicant: BASF AG
Inventor: STEINER GERD , FRANKE ALBRECHT , LENKE DIETER , TESCHENDORF HANS-JUERGEN , WORSTMANN WOLFGANG , KREISKOTT HORST
IPC: A61K31/55 , A61P25/18 , C07D223/20 , C07D401/06 , C07D403/04 , C07D401/04
Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.
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公开(公告)号:FI66365C
公开(公告)日:1984-10-10
申请号:FI793231
申请日:1979-10-18
Applicant: BASF AG
Inventor: TREIBER HANS JOERG , LENKE DIETER , WORSTMANN WOLFGANG
IPC: A61K31/55 , A61K31/553 , A61P25/04 , C07D267/00 , C07D267/12 , C07D267/14
Abstract: PCT No. PCT/EP79/00080 Sec. 371 Date Jun. 26, 1980 Sec. 102(e) Date Jun. 16, 1980 PCT Filed Oct. 22, 1979 PCT Pub. No. WO80/00838 PCT Pub. Date May 1, 1980. The invention relates to novel 1,4-cycloalkano-oxazepines of the general formula where R1 is hydrogen, hydroxyl or alkoxy or acyloxy of 1 to 4 carbon atoms, R2 is a hydrocarbon radical of 1 to 3 carbon atoms, n is 1, 2 or 3 and x is 0 or 1, and of its salts with physiologically acceptable acids; processes for their preparation, and their use in therapy. The novel substances are suitable for the pharmacotherapy of pains of various origins.
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公开(公告)号:CS215038B2
公开(公告)日:1982-06-25
申请号:CS21580
申请日:1980-01-09
Applicant: BASF AG
Inventor: TREIBER HANS J , LENKE DIETER , WORSTMANN WOLFGANG
IPC: A61K31/55 , A61K31/553 , A61P25/04 , C07D267/10
Abstract: Novel hexahydro-1,4-oxazepines of the general formula I I where R1 is hydrogen, or alkyl or acyl each of 1 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and R3 and R4 are identical or different and each is hydrogen or methyl, and their salts with physiologically acceptable acids, processes for their preparation, drugs which contain these compounds, and their use in therapy. The compounds may be used for the pharmacotherapy of pain of various geneses.
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公开(公告)号:CS208458B2
公开(公告)日:1981-09-15
申请号:CS720879
申请日:1979-10-24
Applicant: BASF AG
Inventor: TREIBER HANS J , LENKE DIETER , WORSTMANN WOLFGANG
IPC: A61K31/55 , A61K31/553 , A61P25/04 , C07D267/00 , C07D267/12 , C07D267/14
Abstract: PCT No. PCT/EP79/00080 Sec. 371 Date Jun. 26, 1980 Sec. 102(e) Date Jun. 16, 1980 PCT Filed Oct. 22, 1979 PCT Pub. No. WO80/00838 PCT Pub. Date May 1, 1980. The invention relates to novel 1,4-cycloalkano-oxazepines of the general formula where R1 is hydrogen, hydroxyl or alkoxy or acyloxy of 1 to 4 carbon atoms, R2 is a hydrocarbon radical of 1 to 3 carbon atoms, n is 1, 2 or 3 and x is 0 or 1, and of its salts with physiologically acceptable acids; processes for their preparation, and their use in therapy. The novel substances are suitable for the pharmacotherapy of pains of various origins.
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公开(公告)号:DD150602A5
公开(公告)日:1981-09-09
申请号:DD22101680
申请日:1980-05-09
Applicant: BASF AG
Inventor: STEINER GERG , FRANKE ALBRECHT , LENKE DIETER , TESCHENDORF HANS-JUERGEN , WORSTMANN WOLFGANG , KREISKOTT HORST
IPC: A61K31/55 , A61P25/18 , C07D223/20 , C07D401/06 , C07D403/04
Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.
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公开(公告)号:DD148633A5
公开(公告)日:1981-06-03
申请号:DD21839480
申请日:1980-01-10
Applicant: BASF AG
Inventor: TREIBER HANS J , LENKE DIETER , WORSTMANN WOLFGANG
IPC: A61K31/55 , A61K31/553 , A61P25/04 , C07D267/10
Abstract: Novel hexahydro-1,4-oxazepines of the general formula I I where R1 is hydrogen, or alkyl or acyl each of 1 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and R3 and R4 are identical or different and each is hydrogen or methyl, and their salts with physiologically acceptable acids, processes for their preparation, drugs which contain these compounds, and their use in therapy. The compounds may be used for the pharmacotherapy of pain of various geneses.
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公开(公告)号:AU6278680A
公开(公告)日:1981-04-09
申请号:AU6278680
申请日:1980-09-29
Applicant: BASF AG
Inventor: WIERSDORFF WALTER WIELANT , GEISS KARL-HEINZ , WEIFENBACH HARALD , WORSTMANN WOLFGANG , LENKE DIETER , KRETZSCHMAR ROLF
IPC: A61K31/27 , A61K31/325 , A61K31/34 , A61K31/341 , A61K31/357 , A61K31/38 , A61K31/381 , A61P25/20 , C07C45/62 , C07C45/69 , C07C45/75 , C07C45/79 , C07C45/81 , C07C49/21 , C07C49/337 , C07C49/345 , C07C49/543 , C07C49/553 , C07C49/573 , C07C67/00 , C07C68/02 , C07C68/06 , C07C69/96 , C07C239/00 , C07C271/06 , C07C271/08 , C07C313/00 , C07C319/20 , C07C323/43 , C07D307/14 , C07D307/22 , C07D307/52 , C07D309/04 , C07D309/14 , C07D317/28 , C07D319/06 , C07D333/20 , C07C125/04 , C07C125/065
Abstract: Novel carbamates derived from substituted cyclic beta -keto-alcohols, their preparation, and pharmaceutical formulations which contain these compounds and which may be used as hypnotics in the treatment of sleep disturbance and as sedatives.
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公开(公告)号:NO802862A
公开(公告)日:1981-03-30
申请号:NO802862
申请日:1980-09-26
Applicant: BASF AG
Inventor: WIERSDORFF WALTER-WIELANT , GEISS KARL-HEINZ , WEIFENBACH HARALD , WORSTMANN WOLFGANG , LENKE DIETER , KRETZSCHMAR ROLF
IPC: A61K31/27 , A61K31/34 , A61K31/341 , A61K31/357 , A61K31/38 , A61K31/381 , A61P25/20 , C07C45/62 , C07C45/69 , C07C45/75 , C07C45/79 , C07C45/81 , C07C49/21 , C07C49/337 , C07C49/345 , C07C49/543 , C07C49/573 , C07C67/00 , C07C239/00 , C07C271/06 , C07C271/08 , C07C313/00 , C07C319/20 , C07C323/43 , C07D307/14 , C07D307/22 , C07D307/52 , C07D309/04 , C07D309/14 , C07D317/28 , C07D319/06 , C07D333/20 , C07C
CPC classification number: C07D333/20 , C07C45/62 , C07C45/69 , C07C45/75 , C07C45/79 , C07C45/81 , C07C49/21 , C07C49/337 , C07C49/345 , C07C49/543 , C07C49/573 , C07D307/14 , C07D307/52 , C07D309/04 , C07D309/14 , C07D317/28 , C07D319/06 , Y10S514/923 , C07C49/753
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