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公开(公告)号：AT398470T
公开(公告)日：2008-07-15
申请号：AT02768925
申请日：2002-10-01
Applicant: BAXTER INT
Inventor： KAROOR SUJATHA , DONOVAN BRIAN , HAI TON THAT , KATADA MARI , LU LUIS , MARTIS LEO , MORTI STAVROULA , MUJAIS SALIM , SANDERS PAUL , SOLTYS PAUL , TANDON RAHUL
IPC: A61M1/16 , A61M1/36 , A61M1/28 , A61M1/34 , B01D15/00 , B01J20/02 , B01J20/06 , B01J20/20 , B01J20/22 , B01J39/10 , B01J41/10
Abstract: The invention provides a device (32) for removing uremic toxins in a dialysis procedure comprising a body having an inlet (42) and an outlet (44) and defining an interior. The interior includes a layer comprising urease, a layer comprising zirconium oxide, a layer comprising zirconium phosphate, and a layer comprising carbon. The device is constructed and arranged so that a fluid entering the device contacts the zirconium phosphate layer before contacting the urease layer and before contacting the zirconium oxide layer.
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公开(公告)号：AU2013209534A1
公开(公告)日：2014-08-07
申请号：AU2013209534
申请日：2013-01-18
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： KAROOR SUJATHA
Abstract: A dialysis system comprising: a sorbent cartridge in fluid communication with at least one of a patient or a dialyzer, the sorbent cartridge including a housing having a zirconium phosphate layer followed by at least one of a urease layer, a zirconium oxide layer, or a carbon layer; a storage container in fluid communication with the sorbent cartridge; a pump in fluid communication sorbent cartridge and the storage container; and a control unit in operable communication with the pump, wherein the control unit is programmed to cause the pump to pump a dialysis fluid to flow (i) in a first direction through the sorbent cartridge, wherein the zirconium phosphate layer is contacted by the dialysis fluid before the at least one of the urease layer, zirconium oxide layer or carbon layer and (ii) in a second direction, reverse from the first direction, through the sorbent cartridge wherein the at least one of the urease layer, zirconium oxide layer or carbon layer is contacted by the dialysis fluid before the zirconium phosphate layer.
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公开(公告)号：PL2211874T3
公开(公告)日：2014-05-30
申请号：PL08838014
申请日：2008-10-07
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RISER BRUCE L , ZIESKE PAUL , KAROOR SUJATHA , PATEL HIMANSHU D
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公开(公告)号：AU2012216797A1
公开(公告)日：2012-10-04
申请号：AU2012216797
申请日：2012-09-12
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RISER BRUCE L , ZIESKE PAUL , KAROOR SUJATHA , PATEL HIMANSHU D
Abstract: A heat sterilized solution includes a pyrophosphate and a bicarbonate buffer, the solution having a pH greater than 7, wherein the bicarbonate buffer and the pH greater than 7 heat stabilize the pyrophosphate. The solution can be part of a heat sterilized dialysis product that also includes another part comprising a dialysis component selected from the group consisting of osmotic agents, electrolytes and combinations thereof. 1 1 Inn- 1)
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公开(公告)号：DE60227189D1
公开(公告)日：2008-07-31
申请号：DE60227189
申请日：2002-10-01
Applicant: BAXTER INT
Inventor： KAROOR SUJATHA , DONOVAN BRIAN , HAI TON THAT , KATADA MARI , LU LUIS , MARTIS LEO , MORTI STAVROULA , MUJAIS SALIM , SANDERS PAUL , SOLTYS PAUL , TANDON RAHUL
IPC: A61M1/16 , A61M1/36 , A61M1/28 , A61M1/34 , B01D15/00 , B01J20/02 , B01J20/06 , B01J20/20 , B01J20/22 , B01J39/10 , B01J41/10
Abstract: The invention provides a device (32) for removing uremic toxins in a dialysis procedure comprising a body having an inlet (42) and an outlet (44) and defining an interior. The interior includes a layer comprising urease, a layer comprising zirconium oxide, a layer comprising zirconium phosphate, and a layer comprising carbon. The device is constructed and arranged so that a fluid entering the device contacts the zirconium phosphate layer before contacting the urease layer and before contacting the zirconium oxide layer.
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Patent Agency Ranking
公开(公告)号：AU2003249296A1
公开(公告)日：2004-02-09
申请号：AU2003249296
申请日：2003-07-16
Applicant: BAXTER INT
Inventor： CHILDERS ROBERT W , BROWN DAVID S , WARIAR RAMESH , KAROOR SUJATHA , DIN SHAHID , MARTIS LEO , BUCHMANN CODY , SOLTYS PAUL
Abstract: A system for dialysis is disclosed. An example peritoneal dialysis system includes a peritoneal dialysis machine including a pumping mechanism, and a sensor configured to measure a property of peritoneal dialysis fluid. The peritoneal dialysis system also includes a disposable cassette operable with the peritoneal dialysis machine. The disposable cassette includes a fluid source inlet for accepting fluid from a fluid source and a fluid flow path in fluid communication with the fluid source inlet. The fluid flow path includes a pump chamber operable with the pumping mechanism to pump fluid through the fluid flow path. The disposable cassette also includes a concentrate inlet for fluidly communicating concentrate to the fluid flow path, and a sensor chamber located along the fluid flow path and operable with the sensor. The sensor is configured to provide feedback to the peritoneal dialysis machine for mixing the concentrate for forming peritoneal dialysis fluid.
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公开(公告)号：AU2003237362A8
公开(公告)日：2003-12-31
申请号：AU2003237362
申请日：2003-06-03
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： YEH ROSA , TANDON RAHUL , KAROOR SUJATHA , PAULEY ROBIN , BOGGS DANIEL
Abstract: Membranes impregnated with cross-linked enzyme crystals and devices, systems and methods of producing and using same are provided. The present invention includes membranes impregnated with a sufficient amount of a cross-linked enzyme crystal(s), such as membranes impregnated with cross-linked urease crystals. The membrane can been dried in a glycerol solution prior to use.
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公开(公告)号：CA2754522C
公开(公告)日：2019-08-20
申请号：CA2754522
申请日：2010-03-05
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , MILLIPORE CORP
Inventor： MILLER JOSHUA J , ROHDE JUSTIN , KAROOR SUJATHA , LO YING-CHENG , DING YUANPANG S , DUPONT STEPHANE
Abstract: Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodeionization capabilities are provided. In an embodiment, the dialysis system (10) includes a carbon source (40), a urease source (50) and an electrodeionization unit (30). The carbon source (40) and urease source (50) can be in the form of removable cartridges.
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公开(公告)号：CA2701763C
公开(公告)日：2017-04-18
申请号：CA2701763
申请日：2008-10-07
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： RISER BRUCE L , ZIESKE PAUL , KAROOR SUJATHA , PATEL HIMANSHU D
Abstract: Dialysis solutions comprising pyrophosphates and methods of making and using the dialysis solutions are provided. In an embodiment, the present disclosure provides a dialysis solution comprising a stable and therapeutically effective amount of pyrophosphate. The dialysis solution can be sterilized, for example, using a technique such as autoclave, steam, high pressure, ultra-violet, filtration or combination thereof. The dialysis solution can be in the form of a concentrate.
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公开(公告)号：AU2013209534B2
公开(公告)日：2016-09-08
申请号：AU2013209534
申请日：2013-01-18
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： KAROOR SUJATHA
Abstract: A dialysis system comprising: a sorbent cartridge in fluid communication with at least one of a patient or a dialyzer, the sorbent cartridge including a housing having a zirconium phosphate layer followed by at least one of a urease layer, a zirconium oxide layer, or a carbon layer; a storage container in fluid communication with the sorbent cartridge; a pump in fluid communication sorbent cartridge and the storage container; and a control unit in operable communication with the pump, wherein the control unit is programmed to cause the pump to pump a dialysis fluid to flow (i) in a first direction through the sorbent cartridge, wherein the zirconium phosphate layer is contacted by the dialysis fluid before the at least one of the urease layer, zirconium oxide layer or carbon layer and (ii) in a second direction, reverse from the first direction, through the sorbent cartridge wherein the at least one of the urease layer, zirconium oxide layer or carbon layer is contacted by the dialysis fluid before the zirconium phosphate layer.
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