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    SYSTEMS FOR PERFORMING HEMODIALYSIS
    1.
    发明申请
    SYSTEMS FOR PERFORMING HEMODIALYSIS 审中-公开
    用于执行肝细胞分析的系统

    公开(公告)号：WO2010051207A3

    公开(公告)日：2010-07-01

    申请号：PCT/US2009061589

    申请日：2009-10-22

    Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  WATKINS RANDOLPH H ,  MALIEKKAL SHINCY ,  KAROOR SUJATHA ,  WURGLER STEVEN J ,  SMITH KATRINA

    Inventor： WATKINS RANDOLPH H ,  MALIEKKAL SHINCY ,  KAROOR SUJATHA ,  WURGLER STEVEN J ,  SMITH KATRINA

    IPC: A61M1/16

    CPC classification number: A61M1/1623 ,  A61M1/26 ,  A61M1/265 ,  A61M1/3472 ,  A61M1/3479 ,  B01D63/16 ,  B01D65/08 ,  B01D2315/02 ,  B01D2321/2033

    Abstract: Systems and methods for performing hemodialysis to remove metabolic waste from the blood of a patient are disclosed. The systems and methods preferably comprise at (east one blood processing apparatus that receives whole blood from a patient. Cellular blood components are removed from the whole blood by hemoftitration, to provide filtered plasma comprising metabolic waste that is substantially reduced of blood cells. The cellular blood components may be returned to the patient. The filtered plasma comprising waste may be removed from the blood processing apparatus through a waste path for further processing in a separate apparatus, or in the same apparatus in a second stage processing procedure to remove metabolic waste components and excess water from the plasma by hemodialysis. At least one of the hemofiltration and hemodialysis processing apparatus comprises a Taylor vortex-enhanced separation apparatus.

    Abstract translation: 公开了用于进行血液透析以从患者的血液中除去代谢废物的系统和方法。 该系统和方法优选地包括（东一个血液处理装置，其接收来自患者的全血），通过蒸发法从全血中除去细胞血液成分，以提供包含基本上减少血细胞的代谢废物的过滤血浆，细胞 可以将血液成分返回给患者，包含废物的过滤等离子体可以通过废物路径从血液处理设备中移除，以便在单独的设备中进行进一步处理，或者在第二阶段处理程序中的同一设备中去除代谢废物成分 血液透析中的至少一种血液透析和血液透析处理装置包括泰勒涡旋增强分离装置。

    SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS
    3.
    发明申请
    SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS 审中-公开
    用于执行腹膜透析的系统和方法

    公开(公告)号：WO2004009158A2

    公开(公告)日：2004-01-29

    申请号：PCT/US0322267

    申请日：2003-07-16

    Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

    Inventor： CHILDERS ROBERT W ,  BROWN DAVID S ,  WARIAR RAMESH ,  KAROOR SUJATHA ,  DIN SHAHID ,  MARTIS LEO ,  BUCHMANN CODY ,  SOLTYS PAUL

    IPC: A61M1/14 ,  A61M1/16 ,  A61M1/28

    CPC classification number: A61M1/1696 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/166 ,  A61M1/28 ,  A61M1/284 ,  A61M1/285 ,  A61M1/287 ,  A61M1/288 ,  A61M2202/0413 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2205/3327

    Abstract: In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.

    Abstract translation: 在本发明的腹膜透析实施方案中，来自患者腹膜腔的用过的透析液沿着患者环路通过具有膜的透析器，该膜将废组分与用过的透析液分开，其中患者环路将新鲜透析液返回至患者的腹膜 腔。 废物组分在第二再生回路中被带走到吸收废物组分的再生单元或吸附剂盒。 再生单元除去透析器中由透析器移除的透析液中不需要的成分，例如过量的水（超滤液或UF），毒素和代谢废物。 理想的组分可以通过该系统添加到透析液中，例如葡萄糖和电解质。 添加剂有助于维持患者适当的渗透梯度以进行透析并向患者提供必需的化合物。

    METHOD AND APPARATUS FOR SELECTIVELY REMOVING XENOREACTIVE ANTIBODIES FROM BLOOD, SERUM OR PLASMA
    4.
    发明申请
    METHOD AND APPARATUS FOR SELECTIVELY REMOVING XENOREACTIVE ANTIBODIES FROM BLOOD, SERUM OR PLASMA 审中-公开
    从血液，血清或血浆中选择性地去除感冒性抗体的方法和装置

    公开(公告)号：WO0041718A9

    公开(公告)日：2001-09-20

    申请号：PCT/US0000410

    申请日：2000-01-10

    Applicant: BAXTER INT

    Inventor： KAROOR SUJATHA ,  HENDERSON LEE ,  MOLINA JEANETTE

    IPC: A61M1/34 ,  A61P37/06 ,  B01J20/28 ,  B01J20/32 ,  A61K39/00

    CPC classification number: A61M1/3486 ,  A61M1/3472 ,  A61M1/3475 ,  B01J20/28033 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3274

    Abstract: A method and apparatus for selectively removing xenoreactive antibodies from blood, serum or plasma are provided wherein a ligand capable of binding to xenoreactive antibodies is immobilized to an immunoaffinity membrane, and the blood, serum or plasma is passed through the ligand-containing immunoaffinity membrane so that xenoreactive antibodies are removed from the blood, serum or plasma prior to its reintroduction into a patient. The invention allows for specific removal of only those xenoreactive antibodies associated with the hyperacute rejection observed when organs or tissues from certain non-human animals come in contact with human blood or blood fluids, as would occur during xenotransplantation. The invention is advantageous in that it can be carried out simply and efficiently using a single piece of equipment, and the invention will be useful in reducing or eliminating the hyperacute rejection and rapid destruction of graft tissue that would normally occur following xenotransplantation.

    Abstract translation: 提供了一种从血液，血清或血浆中选择性去除异反应性抗体的方法和装置，其中能够结合异反应性抗体的配体被固定在免疫亲和膜上，血液，血清或血浆通过含配体的免疫亲和膜 在将其再次引入患者之前，从血液，血清或血浆中除去异反应性抗体。 如在异种移植期间发生的那样，本发明允许特异性地去除与来自某些非人类动物的器官或组织接触人类血液或血液的超急性排斥相关的那些异反应性抗体。 本发明的优点在于其可以使用单件设备简单有效地进行，并且本发明可用于减少或消除通常在异种移植后发生的超急性排斥和移植组织的快速破坏。

    Systems and methods for performing peritoneal dialysis
    6.
    发明专利
    Systems and methods for performing peritoneal dialysis 未知

    公开(公告)号：AU2003249296A8

    公开(公告)日：2004-02-09

    申请号：AU2003249296

    申请日：2003-07-16

    Applicant: BAXTER HEALTHCARE SA ,  BAXTER INT

    Inventor： CHILDERS ROBERT W ,  BROWN DAVID S ,  WARIAR RAMESH ,  KAROOR SUJATHA ,  DIN SHAHID ,  MARTIS LEO ,  BUCHMANN CODY ,  SOLTYS PAUL

    IPC: A61M1/14 ,  A61M1/16 ,  A61M1/28

    Abstract: A system for dialysis is disclosed. An example peritoneal dialysis system includes a peritoneal dialysis machine including a pumping mechanism, and a sensor configured to measure a property of peritoneal dialysis fluid. The peritoneal dialysis system also includes a disposable cassette operable with the peritoneal dialysis machine. The disposable cassette includes a fluid source inlet for accepting fluid from a fluid source and a fluid flow path in fluid communication with the fluid source inlet. The fluid flow path includes a pump chamber operable with the pumping mechanism to pump fluid through the fluid flow path. The disposable cassette also includes a concentrate inlet for fluidly communicating concentrate to the fluid flow path, and a sensor chamber located along the fluid flow path and operable with the sensor. The sensor is configured to provide feedback to the peritoneal dialysis machine for mixing the concentrate for forming peritoneal dialysis fluid.

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