公开(公告)号：CA2171588A1

公开(公告)日：1996-09-17

申请号：CA2171588

申请日：1996-03-12

Applicant: BIO RAD LABORATORIES

Inventor： HEFFELFINGER DAVID M ,  WITNEY FRANKLIN R

IPC: G01N21/91 ,  G01N21/25 ,  G01N21/64 ,  G01N21/77 ,  C12Q1/68

Abstract: A method and apparatus to detect fluorescence from a sample is provided. The optical system allows the user to continuously tune the wavelengths and bandwidths of the excitation source and the emission detection system. A peaking function automatically peaks the detected fluorescent signal by fine tuning the excitation and emission detection systems. A look-up table allows the fluorescent signal for a specific wavelength to be corrected for the wavelength dependence of the optical train. In one embodiment of the system the sample is simultaneously irradiated in more than one wavelength band, each wavelength band being independently tunable.

公开(公告)号：FR2664703B1

公开(公告)日：1995-05-12

申请号：FR9108381

申请日：1991-07-04

Applicant: BIO RAD LABORATORIES

Inventor： BERS GEORGE ,  WITNEY FRANKLIN R

IPC: C12Q1/42 ,  C12Q1/68 ,  G01N21/76 ,  G01N21/78 ,  G01N33/58 ,  G01N33/68 ,  G01N33/52

公开(公告)号：HK40795A

公开(公告)日：1995-03-31

申请号：HK40795

申请日：1995-03-23

Applicant: BIO RAD LABORATORIES

Inventor： BERS GEORGE ,  WITNEY FRANKLIN R

IPC: C12Q1/42 ,  C12Q1/68 ,  G01N21/76 ,  G01N21/78 ,  G01N33/58 ,  G01N33/68

公开(公告)号：CA2241364A1

公开(公告)日：1997-07-03

申请号：CA2241364

申请日：1996-12-20

Applicant: BIO RAD LABORATORIES

Inventor： WITNEY FRANKLIN R ,  HEFFELFINGER DAVID M

IPC: G01N33/566 ,  C12N15/09 ,  C12Q1/68 ,  G01B9/02 ,  G01N21/45

Abstract: The invention relates to a method of identifying the individual autosomal and sex chromosomes of a human karyotype through the use of a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hydridizing with one predetermined autosomal or sex chromosome of a human karyotype. The invention additionally relates to an interferometer that is used in such method.

公开(公告)号：SG14195G

公开(公告)日：1995-06-16

申请号：SG14195

申请日：1995-01-26

Applicant: BIO RAD LABORATORIES

Inventor： BERS GEORGE ,  WITNEY FRANKLIN R

IPC: G01N21/76

公开(公告)号：GB2246197B

公开(公告)日：1994-03-16

申请号：GB9115090

申请日：1991-07-12

Applicant: BIO RAD LABORATORIES

Inventor： BERS GEORGE ,  WITNEY FRANKLIN R

IPC: C12Q1/42 ,  C12Q1/68 ,  G01N21/76 ,  G01N21/78 ,  G01N33/58 ,  G01N33/68