公开(公告)号：WO2018080499A1

公开(公告)日：2018-05-03

申请号：PCT/US2016/059147

申请日：2016-10-27

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： SIMON, Eric ,  PORTER-MALONEY, Venda ,  PATEL, Vyoma

IPC: A61Q11/00 ,  A61K8/19 ,  A61K8/27 ,  A61K8/03 ,  A61K8/365 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49

Abstract: A dual-phase mouthwash composition for whitening teeth is disclosed. The dual-phase mouthwash composition includes an orally acceptable vehicle having a hydrophilic phase and a hydrophobic phase, a blue dye and/or blue pigment having a blue to blue-violet color with a hue angle in the CIELAB system from about 200 to about 320 degrees, and a zinc salt.

Abstract translation: 公开了一种用于美白牙齿的双相漱口剂组合物。 双相漱口剂组合物包含具有亲水相和疏水相的口腔可接受的载体，具有蓝色至蓝紫色的蓝色染料和/或蓝色颜料，CIELAB系统中的色调角为约200至约320 度，和锌盐。

公开(公告)号：WO2017219339A1

公开(公告)日：2017-12-28

申请号：PCT/CN2016/086994

申请日：2016-06-24

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  WON, Betty ,  MANUS, Lisa ,  STRANICK, Michael A. ,  YAN, Peng ,  TAN, Chengkang ,  PATEL, Vyoma ,  MORGAN, Andre Michelle ,  POTANIN, Andrei ,  HUANG, Xiaoyi

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/25 ,  A61K8/21 ,  A61Q11/00

Abstract: An oral care composition comprises (a) arginine or lysine; (b) zinc citrate and zinc oxide; (c) fluoride source; and (d) a silica abrasive which exhibits an acid pH when measured as an aqueous slurry. The composition is used in the manufacture of a product for application to the oral cavity of a subject in need thereof to improve oral health.

Abstract translation: 口腔护理组合物包含（a）精氨酸或赖氨酸; （b）柠檬酸锌和氧化锌; （c）氟化物源; 和（d）当以含水浆液测量时呈现酸性pH的二氧化硅研磨剂。 该组合物用于制造用于需要其的受试者的口腔以改善口腔健康的产品。

公开(公告)号：WO2014185884A1

公开(公告)日：2014-11-20

申请号：PCT/US2013/040694

申请日：2013-05-13

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： JOZIAK, Marilou ,  PATEL, Vyoma ,  PRENCIPE, Michael

IPC: A61K8/44 ,  A61Q11/00 ,  A61K8/96 ,  A61K8/19

CPC classification number: A61K8/965 ,  A61K8/0204 ,  A61K8/0241 ,  A61K8/19 ,  A61K8/21 ,  A61K8/44 ,  A61K2800/28 ,  A61K2800/41 ,  A61K2800/412 ,  A61K2800/592 ,  A61Q11/00

Abstract: Disclosed are oral care compositions comprising an abrasive system, wherein the abrasive system comprises (a) a first particulate abrasive comprising at least 20 wt% pumice, based on the weight of the oral care composition, having an average particle size of from 20 to 300 microns; and (b) a second particulate abrasive comprising calcium carbonate having an average particle size of from 2 to 13 microns. There is also disclosed a method of cleaning teeth comprising applying the oral care composition to a tooth surface, the oral care composition being applied as a paste disposed in a prophy cup.

Abstract translation: 公开了包含磨料体系的口腔护理组合物，其中磨料体系包含（a）基于口腔护理组合物的重量，包含至少20重量％浮石的平均粒度为20至300的第一颗粒磨料 微米; 和（b）包含平均粒径为2至13微米的碳酸钙的第二颗粒磨料。 还公开了一种清洁牙齿的方法，包括将口腔护理组合物施用于牙齿表面，所述口腔护理组合物作为糊状物应用于植入杯中。

公开(公告)号：EP3344219A1

公开(公告)日：2018-07-11

申请号：EP17737129.1

申请日：2017-06-23

Applicant: Colgate-Palmolive Company

Inventor： POTANIN, Andrei ,  POTH, Tilo ,  AHUJA, Amit ,  BLANVALET, Claude ,  WON, Betty ,  MANUS, Lisa ,  STRANICK, Michael, A. ,  HUANG, Xiaoyi ,  PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  YAN, Peng ,  TAN, Chengkang ,  PATEL, Vyoma ,  MORGAN, Andre, Michelle

IPC: A61K8/27 ,  A61K8/44 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/24

CPC classification number: A61K8/44 ,  A61K8/042 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/27 ,  A61K8/34 ,  A61K8/365 ,  A61K8/37 ,  A61K8/442 ,  A61K8/73 ,  A61K8/731 ,  A61K2800/28 ,  A61K2800/48 ,  A61K2800/52 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and a thickening system comprising a nonionic cellulose ether having a viscosity, measured at 2% in water at 25° C., of 4500 to 7500 cps; and a polysaccharide gum; along with methods of making and using same.

公开(公告)号：EP4017457A1

公开(公告)日：2022-06-29

申请号：EP20820742.3

申请日：2020-11-12

Applicant: Colgate-Palmolive Company ,  University of Florida Research Foundation, Inc.

Inventor： ARORA, Payal ,  TRIVEDI, Harsh Mahendra ,  MASTERS, James ,  AHMED, Rabab ,  MELLO, Sarita Vera ,  LEITE, Sergio ,  MALONEY, Venda Porter ,  DIAMOND, Gill ,  PATEL, Vyoma

IPC: A61K8/19 ,  A61K8/25 ,  A61K8/34 ,  A61K8/67 ,  A61Q11/00

公开(公告)号：EP3247324B1

公开(公告)日：2020-01-01

申请号：EP16817201.3

申请日：2016-06-24

Applicant: Colgate-Palmolive Company

Inventor： HUANG, Xiao Yi ,  PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  PATEL, Vyoma ,  WON, Betty ,  YAN, Peng ,  MORGAN, Andre Michelle

IPC: A61K8/27 ,  A61K8/44 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/34

公开(公告)号：EP3544570A1

公开(公告)日：2019-10-02

申请号：EP17830067.9

申请日：2017-12-20

Applicant: Colgate-Palmolive Company

Inventor： MILLER, Jeffrey ,  MALONEY, Venda Porter ,  WU, Donghui ,  PEPPERNEY, Adam ,  SHEN, Hongwei ,  PATEL, Vyoma ,  CHENG, Chi-Yuan

IPC: A61K8/24 ,  A61K8/34 ,  A61K8/36 ,  A61K8/368 ,  A61K8/49 ,  A61Q11/00 ,  A61K8/03 ,  A61K8/20

公开(公告)号：EP3344346A1

公开(公告)日：2018-07-11

申请号：EP17735346.3

申请日：2017-06-23

Applicant: Colgate-Palmolive Company

Inventor： POTH, Tilo ,  POTANIN, Andrei ,  BLANVALET, Claude ,  WON, Betty ,  MANUS, Lisa ,  STRANICK, Michael A. ,  HUANG, Xiao Yi ,  PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  YAN, Peng ,  TAN, Chengkang ,  PATEL, Vyoma ,  MORGAN, Andre Michelle

IPC: A61Q11/00 ,  A61K8/27 ,  A61K8/44 ,  A61K8/73 ,  A61K8/24

Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions.

公开(公告)号：EP3283049A1

公开(公告)日：2018-02-21

申请号：EP16889671.0

申请日：2016-06-24

Applicant: Colgate-Palmolive Company

Inventor： PRENCIPE, Michael ,  RUSSO, Amy ,  STETTLER, Hansruedi ,  WON, Betty ,  MANUS, Lisa ,  STRANICK, Michael A. ,  YAN, Peng ,  TAN, Chengkang ,  PATEL, Vyoma ,  MORGAN, Andre Michelle ,  POTANIN, Andrei ,  HUANG, Xiaoyi

IPC: A61K8/44 ,  A61K8/27 ,  A61K8/25 ,  A61K8/21 ,  A61Q11/00

CPC classification number: A61K8/44 ,  A61K8/042 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/27 ,  A61K8/34 ,  A61K8/365 ,  A61K8/37 ,  A61K8/442 ,  A61K8/73 ,  A61K8/731 ,  A61K2800/28 ,  A61K2800/48 ,  A61K2800/52 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and a thickening system comprising a nonionic cellulose ether having a viscosity, measured at 2% in water at 25° C., of 4500 to 7500 cps; and a polysaccharide gum; along with methods of making and using same.

公开(公告)号：EP2996669B1

公开(公告)日：2017-07-12

申请号：EP13727685.3

申请日：2013-05-13

Applicant: Colgate-Palmolive Company

Inventor： JOZIAK, Marilou ,  PATEL, Vyoma ,  PRENCIPE, Michael ,  MORGAN, Andre

IPC: A61K8/44 ,  A61K8/96 ,  A61K8/19 ,  A61K8/02 ,  A61Q11/00

CPC classification number: A61K8/965 ,  A61K8/0204 ,  A61K8/0241 ,  A61K8/19 ,  A61K8/21 ,  A61K8/44 ,  A61K2800/28 ,  A61K2800/41 ,  A61K2800/412 ,  A61K2800/592 ,  A61Q11/00

Abstract: Disclosed are oral care compositions comprising an abrasive system, wherein the abrasive system comprises (a) a first particulate abrasive comprising at least 20 wt % pumice, based on the weight of the oral care composition, having an average particle size of from 20 to 300 microns; and (b) a second particulate abrasive comprising calcium carbonate having an average particle size of from 2 to 13 microns. There is also disclosed a method of cleaning teeth comprising applying the oral care composition to a tooth surface, the oral care composition being applied as a paste disposed in a prophy cup.

Abstract translation: 公开了包含研磨体系的口腔护理组合物，其中所述研磨体系包含（a）第一颗粒磨料，其基于所述口腔护理组合物的重量包含至少20重量％的平均粒度为20-300 微米; 和（b）包含平均粒度为2至13微米的碳酸钙的第二颗粒磨料。 还公开了一种清洁牙齿的方法，该方法包括将该口腔护理组合物施用于牙齿表面，该口腔护理组合物作为置于预防杯中的糊剂施用。