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公开(公告)号：WO2015094153A1
公开(公告)日：2015-06-25
申请号：PCT/US2013/075306
申请日：2013-12-16
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： D'AMBROGIO, Robert , POTANIN, Andrei , PAN, Guisheng , LIN, Nora
CPC classification number: A61K8/19 , A61K8/24 , A61K8/25 , A61K8/731 , A61K2800/28 , A61K2800/524 , A61Q11/00
Abstract: The present invention provides oral care compositions comprising, by total weight of the composition: (a) 15 to 35 weight % calcium carbonate; and (b) 5 to 25 weight % talc. In one aspect, the total concentration of talc and calcium carbonate in the composition is greater than 35 weight %. In another aspect where the total concentration of talc and calcium carbonate is 35 weight % or less, the composition also includes an additional structuring agent, which comprises at least one of: (i) a cellulose ether thickening agent; and (ii) an inorganic thickening agent selected from thickening silica, a clay thickening agent, and mixtures thereof.
Abstract translation: 本发明提供口腔护理组合物，其包含按组合物的总重量计：（a）15-35重量％的碳酸钙; 和（b）5至25重量％的滑石。 一方面，组合物中滑石和碳酸钙的总浓度大于35重量％。 在滑石和碳酸钙的总浓度为35重量％以下的另一方面，该组合物还包括另外的结构剂，其包含以下至少一种：（i）纤维素醚增稠剂; 和（ⅱ）选自增稠二氧化硅，粘土增稠剂及其混合物的无机增稠剂。
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公开(公告)号：WO2017219339A1
公开(公告)日：2017-12-28
申请号：PCT/CN2016/086994
申请日：2016-06-24
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： PRENCIPE, Michael , RUSSO, Amy , STETTLER, Hansruedi , WON, Betty , MANUS, Lisa , STRANICK, Michael A. , YAN, Peng , TAN, Chengkang , PATEL, Vyoma , MORGAN, Andre Michelle , POTANIN, Andrei , HUANG, Xiaoyi
Abstract: An oral care composition comprises (a) arginine or lysine; (b) zinc citrate and zinc oxide; (c) fluoride source; and (d) a silica abrasive which exhibits an acid pH when measured as an aqueous slurry. The composition is used in the manufacture of a product for application to the oral cavity of a subject in need thereof to improve oral health.
Abstract translation: 口腔护理组合物包含（a）精氨酸或赖氨酸; （b）柠檬酸锌和氧化锌; （c）氟化物源; 和（d）当以含水浆液测量时呈现酸性pH的二氧化硅研磨剂。 该组合物用于制造用于需要其的受试者的口腔以改善口腔健康的产品。
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公开(公告)号：WO2017223496A1
公开(公告)日：2017-12-28
申请号：PCT/US2017/039080
申请日：2017-06-23
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： HUANG, Xiaoyi , JOSIAS, Wilbens , PRENCIPE, Michael , STRANICK, Michael, A. , WON, Betty , MAURAO, Marcella , RUSSO, Amy , MANUS, Lisa , STETTLER, Hansruedi , PATEL, Vyoma , MORGAN, Andre, Michelle , POTANIN, Andrei , TAN, Chengkang , YAN, Peng
Abstract: Described herein are oral care compositions comprising a basic amino acid; a combination of zinc ion sources; and from about 0.75 wt.% to about 2 wt.% of a chelating system; along with methods of making and using same.
Abstract translation: 本文描述了包含碱性氨基酸的口腔护理组合物; 锌离子源的组合; 和约0.75重量％至约2重量％的螯合体系; 以及制作和使用它们的方法。
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公开(公告)号：WO2015094154A1
公开(公告)日：2015-06-25
申请号：PCT/US2013/075310
申请日：2013-12-16
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： D'AMBROGIO, Robert , POTANIN, Andrei , PAN, Guisheng , LIN, Nora
CPC classification number: A61K8/36 , A61K8/19 , A61K8/24 , A61K8/25 , A61K8/26 , A61K8/345 , A61K8/73 , A61K8/731 , A61K2800/28 , A61K2800/48 , A61K2800/592 , A61Q11/00
Abstract: The present invention provides an oral care composition comprising, by total weight of the composition: (a) 15 to 35 weight % calcium carbonate; (b) 0.5 to 2 weight % cellulose ether thickening agent; (c) 1 to 6 weight % clay thickening agent; and (d) at least 35 weight % water; wherein, when the composition comprises less than 28 weight % calcium carbonate and less than 4 weight % clay thickening agent, the cellulose ether thickening agent is present in an amount of greater than 1 weight %.
Abstract translation: 本发明提供一种口腔护理组合物，其包含组合物的总重量：（a）15至35重量％的碳酸钙; （b）0.5〜2重量％纤维素醚增稠剂; （c）1〜6重量％粘土增稠剂; 和（d）至少35重量％的水; 其中当所述组合物包含小于28重量％的碳酸钙和小于4重量％的粘土增稠剂时，纤维素醚增稠剂的存在量大于1重量％。
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公开(公告)号：WO2023059869A1
公开(公告)日：2023-04-13
申请号：PCT/US2022/046022
申请日：2022-10-07
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： MALONEY, Venda, Porter , DU-THUMM, Laurence , RINAUDI MARRON, Luciana , LAVENDER, Stacey , PATEL, Vyoma , MAKWANA, Ekta , POTANIN, Andrei , TEOMAN, Baran , POTNIS, Shashank , PATEL, Gayatri, Sachin , MYERS, Carl
IPC: A61K8/02 , A61K8/44 , A61K8/65 , A61K8/73 , A61Q11/00 , A23G3/36 , A23G3/42 , A23G3/44 , A23G3/364 , A61K2800/92 , A61K8/0216 , A61K8/042
Abstract: Disclosed herein are oral compositions comprising an amino acid and a gelling agent. In certain embodiments, the chewable composition is in the form of a gummy comprising arginine and pectin. Related kits and methods of use are further provided.
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Patent Agency Ranking
公开(公告)号：WO2022098730A1
公开(公告)日：2022-05-12
申请号：PCT/US2021/057861
申请日：2021-11-03
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： MANUS, Lisa , STEELE, Joseph , PICQUET, Guillaume , PADULA, Christine , CHEN, Dandan , WON, Betty , POTANIN, Andrei
Abstract: The present invention relates to oral hydrogel compositions, more particularly to thermosensitive gel compositions, which undergo a sol-gel transition in the oral cavity, and which optionally comprise therapeutic actives for sustained release.
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公开(公告)号：WO2017223497A1
公开(公告)日：2017-12-28
申请号：PCT/US2017/039084
申请日：2017-06-23
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： POTH, Tilo , POTANIN, Andrei , BLANVALET, Claude , WON, Betty , MANUS, Lisa , STRANICK, Michael A. , HUANG, Xiaoyi , PRENCIPE, Michael , RUSSO, Amy , STETTLER, Hansruedi , YAN, Peng , TAN, Chengkang , PATEL, Vyoma , MORGAN, Andre Michelle
Abstract: Described herein are oral care compositions comprising an amino acid; a combination of zinc ion sources; and a thickening system comprising a nonionic cellulose ether having a molecular weight of from about 300,000 to about 350,000; and a polysaccharide gum; along with methods of making and using same.
Abstract translation: 本文描述了包含氨基酸的口腔护理组合物; 锌离子源的组合; 和增稠体系，其包含分子量为约300,000至约350,000的非离子纤维素醚; 和多糖胶; 以及制作和使用它们的方法。
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公开(公告)号：WO2015016840A1
公开(公告)日：2015-02-05
申请号：PCT/US2013/052755
申请日：2013-07-30
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： TOH, Kiat-Cheong , POTANIN, Andrei
Abstract: A refill dispensing bottle (1), comprising: a container (200) defining a chamber (220) storing a viscous flowable substance and having an opening (240) through which the substance is dispensable from the chamber; and a dispenser (100) comprising a seal (110) sealing the opening, a substance flow passageway fluidly connecting the chamber to an exterior of the container through the seal, and a vent (130) fluidly connecting the chamber to the exterior of the container through the seal in parallel with the substance flow passageway; wherein a cross- sectional area of the substance flow passageway, a cross-sectional area of the vent, and a viscosity of the substance are selected so that the substance at room temperature and atmospheric pressure is dispensed from the substance flow passageway at a rate of less than 35 cc/sec and at least 0.5 cc/sec with the bottle inverted and the vent unblocked.
Abstract translation: 一种再填充分配瓶（1），包括：容器（200），其限定存储粘性可流动物质并具有开口（240）的室（220），所述物质可从所述室中分配; 以及分配器（100），其包括密封所述开口的密封件（110），通过所述密封件将所述腔室流体地连接到所述容器的外部的物质流动通道;以及将所述腔室流体连接到所述容器的外部的通气孔 通过与物质流通道平行的密封; 其中选择物质流通道的横截面面积，排气口的横截面积和物质的粘度，使得物质在室温和大气压下以物质流动通道的速度被分配 小于35cc / sec和至少0.5cc / sec，瓶倒置并且排气口不被堵塞。
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公开(公告)号：WO2017112667A1
公开(公告)日：2017-06-29
申请号：PCT/US2016/067773
申请日：2016-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： SZEWCZYK, Gregory , MANUS, Lisa , SCHAEFFER-KORBYLO, Lyndsay , POTANIN, Andrei , SUBRAMANYAM, Ravi
CPC classification number: A61K8/27 , A61K8/21 , A61K8/24 , A61K8/44 , A61K8/8176 , A61K8/8182 , A61K2800/58 , A61Q11/00 , A61Q11/02
Abstract: Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and linear polyvinylpyrrolidone and/or sodium tripolyphosphate, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.
Abstract translation: 本文公开了包含锌氨基酸卤化物配合物和线性聚乙烯吡咯烷酮和/或三聚磷酸钠的口腔护理组合物，所述组合物具有改善的流变稳定性。 还提供了制造和使用该组合物的方法。
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公开(公告)号：WO2015094152A1
公开(公告)日：2015-06-25
申请号：PCT/US2013/075304
申请日：2013-12-16
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： D'AMBROGIO, Robert , POTANIN, Andrei , PAN, Guisheng , LIN, Nora
CPC classification number: A61K8/36 , A61K8/19 , A61K8/24 , A61K8/25 , A61K8/34 , A61K8/345 , A61K8/731 , A61K2800/28 , A61K2800/48 , A61K2800/524 , A61K2800/592 , A61Q11/00
Abstract: The present invention provides an oral care composition comprising, based on the total weight of the composition: (a) 15 to 24 weight % calcium carbonate; (b) 0.9 to 2.5 weight % cellulose ether thickening agent; (c) 7 to 10 weight % thickening silica; and (d) at least 40 weight % water.
Abstract translation: 本发明提供一种口腔护理组合物，其包含基于组合物的总重量：（a）15至24重量％的碳酸钙; （b）0.9至2.5重量％的纤维素醚增稠剂; （c）7至10重量％增稠二氧化硅; 和（d）至少40重量％的水。
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