公开(公告)号：EP2729190A1

公开(公告)日：2014-05-14

申请号：EP12737197.9

申请日：2012-07-10

Applicant: Coloplast A/S

Inventor： EVERLAND, Hanne ,  OSTHER, Kurt ,  VANGE, Jakob ,  NIELSEN, Lene Feldskov

IPC: A61L15/26 ,  A61L15/38

CPC classification number: A61F13/00991 ,  A61L15/26 ,  A61L15/32 ,  A61L15/38 ,  A61L15/425 ,  A61L2400/04 ,  C08L75/04

Abstract: The present invention relates to method of preparing an absorbent wound care device comprising an active agent on a wound contacting surface, such as e.g. a protein or an enzyme, by the use of electrospraying, and a wound care device obtained by said method. The invention further relates to a wound care device comprising Thrombin and a polyurethane foam, and a method of treating bleeding.

公开(公告)号：EP3668555A1

公开(公告)日：2020-06-24

申请号：EP18769588.7

申请日：2018-08-16

Applicant: Coloplast A/S

Inventor： VANGE, Jakob

IPC: A61L29/08 ,  A61L29/14

公开(公告)号：EP2451490A1

公开(公告)日：2012-05-16

申请号：EP10730698.7

申请日：2010-07-06

Applicant: Coloplast A/S

Inventor： EVERLAND, Hanne ,  NIELSEN, Lene, Feldskov ,  VANGE, Jakob ,  GALLEGO, Monica, Ramos

IPC: A61L27/12 ,  A61L27/38 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61B17/08 ,  A61F2/00 ,  A61F5/48

CPC classification number: A61F2/0045 ,  A61B17/0057 ,  A61F2/0063 ,  A61L27/12 ,  A61L27/38 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/236 ,  A61L2300/414 ,  A61L2300/43 ,  A61L2300/604 ,  C08L67/04

Abstract: The present invention relates to new reinforced biodegradable scaffolds for soft tissue regeneration, as well as methods for support and for augmentation and regeneration of living tissue, wherein a reinforced biodegradable scaffold is used for the treatment of indications, where increased strength and stability is required besides the need for regeneration of living tissue within a patient. The present invention further relates to the use of scaffolds together with cells or tissue explants for soft tissue regeneration, such as in the treatment of a medical prolapse, such as rectal or pelvic organ prolapse, or hernia.

Abstract translation: 本发明涉及用于软组织再生的新的增强的可生物降解支架，以及用于支撑和增加和再生生物体组织的方法，其中增强的可生物降解的支架用于治疗适应症，其中需要增加强度和稳定性， 需要在患者体内再生活组织。 本发明还涉及支架与细胞或组织外植体一起用于软组织再生，例如用于治疗医学脱垂，例如直肠或盆腔器官脱垂或疝气的用途。

公开(公告)号：EP1996643A1

公开(公告)日：2008-12-03

申请号：EP07711258.9

申请日：2007-03-07

Applicant: Coloplast A/S

Inventor： VANGE, Jakob ,  SCHWACH-ABDELLAOUI, Khadija ,  EVERLAND, Hanne ,  NIELSEN, Peter, Sylvest ,  NIELSEN, Brian ,  JESPERSEN, Lene, Karin ,  NIELSEN, Lene, Feldskov

IPC: C08G63/664 ,  C08G81/00 ,  C08J9/00 ,  C08J9/28 ,  A61L27/18 ,  A61L15/26 ,  A61L27/56

CPC classification number: C08G63/664 ,  A61L15/26 ,  A61L15/425 ,  A61L27/18 ,  A61L27/56 ,  C08G2261/126 ,  C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2367/04 ,  C12N5/0068 ,  C12N2533/30 ,  C12N2533/40 ,  Y10T428/249958 ,  C08L67/04

Abstract: The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A-O-(CHR1CHR2O)n-B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [-CH(CH3)-COO-] and (ii) glycolide units [-CH2-COO-] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C1-6-alkyl or hydroxy protecting groups, one of R1 and R2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [-(CHR1CHR2O)-] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.

公开(公告)号：EP1322168B1

公开(公告)日：2004-11-24

申请号：EP01971722.2

申请日：2001-09-26

Applicant: COLOPLAST A/S

Inventor： VANGE, Jakob ,  NIELSEN, Brian

IPC: A01N59/16 ,  A01N43/50 ,  A01N43/54

CPC classification number: A61L29/085 ,  A01N43/50 ,  A01N43/54 ,  A01N59/16 ,  A61L26/0066 ,  A61L29/16 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/802 ,  C07D233/74 ,  C07D233/80 ,  C07D233/88 ,  C07D239/62 ,  A01N25/34 ,  A01N25/22 ,  A01N25/16 ,  A01N25/04 ,  A01N2300/00

公开(公告)号：EP1322168A1

公开(公告)日：2003-07-02

申请号：EP01971722.2

申请日：2001-09-26

Applicant: COLOPLAST A/S

Inventor： VANGE, Jakob ,  NIELSEN, Brian

IPC: A01N59/16 ,  A01N43/50 ,  A01N43/54

CPC classification number: A61L29/085 ,  A01N43/50 ,  A01N43/54 ,  A01N59/16 ,  A61L26/0066 ,  A61L29/16 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/802 ,  C07D233/74 ,  C07D233/80 ,  C07D233/88 ,  C07D239/62 ,  A01N25/34 ,  A01N25/22 ,  A01N25/16 ,  A01N25/04 ,  A01N2300/00

Abstract: A stabilised composition having antibacterial, antiviral and/or antifungal activity, said composition comprising silver ions and a ligand, characterised in that the composition comprises a complex of silver and a ligand selected from the group consisting of 5,5-disubstituted hydantoins in which the substituents do not comprise conjugated unsaturated bonds and barbituric acid and derivatives thereof stabilising silver ions against reduction to free silver in a hydrophilic environment, and that the composition has a solubility in water higher than 10 mg Ag/l is stable during sterilisation and retains the activity without giving rise to darkening or discoloration of the dressing during storage.

Abstract translation: 一种具有抗细菌，抗病毒和/或抗真菌活性的稳定化组合物，所述组合物包含银离子和配体，其特征在于所述组合物包含银和选自5,5-二取代乙内酰脲的配体的配合物，其中 取代基不包含共轭不饱和键和巴比妥酸及其衍生物稳定银离子以在亲水环境中还原成游离的银，并且该组合物在水中的溶解度高于10mg Ag / l在灭菌期间是稳定的并保持活性 而不会在储存期间引起敷料变黑或变色。

公开(公告)号：EP4514410A1

公开(公告)日：2025-03-05

申请号：EP23723133.7

申请日：2023-04-28

Applicant: Coloplast A/S

Inventor： VANGE, Jakob ,  STROEBECH, Esben ,  LARSEN, Esben Kjaer Unmack

IPC: A61L26/00

公开(公告)号：EP2021536B1

公开(公告)日：2014-02-26

申请号：EP07728445.3

申请日：2007-04-24

Applicant: Coloplast A/S

Inventor： HASSINGBOE, Jens ,  VANGE, Jakob ,  EVERLAND, Hanne

IPC: D01F4/00 ,  D04H3/04 ,  A61L15/32 ,  A61L27/22

CPC classification number: A61L15/32 ,  A61L15/42 ,  A61L27/222 ,  B29C47/0004 ,  B29K2089/00 ,  D01D5/04 ,  D01D5/14 ,  D01F4/00 ,  D04H1/42 ,  D04H1/4374 ,  D04H1/4382 ,  D04H3/00 ,  D04H3/073 ,  D04H3/12 ,  D04H3/16 ,  D04H13/00 ,  Y10T428/2927 ,  Y10T428/2933 ,  Y10T442/60

公开(公告)号：EP2291205A2

公开(公告)日：2011-03-09

申请号：EP09715535.2

申请日：2009-03-02

Applicant: Coloplast A/S

Inventor： EVERLAND, Hanne ,  SAMUELSEN, Peter ,  VANGE, Jakob ,  CLAUSEN, Christian ,  GALLEGO, Monica Ramos

IPC: A61L27/18 ,  A61L27/38 ,  A61L27/56 ,  A61L27/58

CPC classification number: A61L27/3604 ,  A61L27/18 ,  A61L27/38 ,  A61L27/56 ,  A61L2400/06 ,  Y10T428/2982 ,  C08L67/04

Abstract: The present invention provides for a composition, for augmentation and regeneration of living tissue in a subject, comprising a population of porous microparticles of a biodegradable polymer, one or more mammalian cell populations, and optionally, a biocompatible adhesive.

公开(公告)号：EP1996643B8

公开(公告)日：2010-04-07

申请号：EP07711258.9

申请日：2007-03-07

Applicant: Coloplast A/S

Inventor： VANGE, Jakob ,  SCHWACH-ABDELLAOUI, Khadija ,  EVERLAND, Hanne ,  NIELSEN, Peter, Sylvest ,  NIELSEN, Brian ,  JESPERSEN, Lene, Karin ,  NIELSEN, Lene, Feldskov

IPC: C08G63/664 ,  C08G81/00 ,  C08J9/00 ,  C08J9/28 ,  A61L27/18 ,  A61L15/26 ,  A61L27/56

CPC classification number: C08G63/664 ,  A61L15/26 ,  A61L15/425 ,  A61L27/18 ,  A61L27/56 ,  C08G2261/126 ,  C08J9/28 ,  C08J2201/0482 ,  C08J2201/0484 ,  C08J2367/04 ,  C12N5/0068 ,  C12N2533/30 ,  C12N2533/40 ,  Y10T428/249958 ,  C08L67/04

Abstract: The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A-O-(CHR1CHR2O)n-B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [-CH(CH3)-COO-] and (ii) glycolide units [-CH2-COO-] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C1-6-alkyl or hydroxy protecting groups, one of R1 and R2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [-(CHR1CHR2O)-] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.