公开(公告)号：IN181657B

公开(公告)日：1998-08-15

申请号：IN494CA1994

申请日：1994-06-27

Applicant: HOECHST AG

Inventor： SCHACH THOMAS ,  PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: C07B39/00 ,  C07C121/52

公开(公告)号：ZA9607366B

公开(公告)日：1997-02-28

申请号：ZA9607366

申请日：1996-08-30

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PFIRMANN RALF ,  KRAUSE STEFAN ,  NEUMANN-GRIMM DORIS

IPC: C07C229/56 ,  C07C

CPC classification number: C07C229/56

公开(公告)号：ZA959411B

公开(公告)日：1996-05-15

申请号：ZA959411

申请日：1995-11-07

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS ,  PFIRMANN RALF

IPC: C07B53/00 ,  C07C253/30 ,  C07C253/34 ,  C07C255/37 ,  C07C

Abstract: Prodn. of cis-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile (1a) and trans-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile (1b), or prodn. of one of (1a) and (1b), comprises a) fractional distillation of a mixt. contg. (1a) + (1b) under reduced pressure to yield a fraction contg. at least 80 wt.% (1a) and a fraction contg. at least 80 wt.% (1b); and (b) purifying the fractions further by fractional crystallisation or melt crystallisation; or (c) isomerising one fraction to the thermodynamic equilibrium mixt. of (1a) + (1b) and returning to step a). Cis-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile of formula (Ia) and the trans isomer of formula (1b) are new.

公开(公告)号：ZA9509411B

公开(公告)日：1996-05-15

申请号：ZA9509411

申请日：1995-11-07

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS ,  PFIRMANN RALF

IPC: C07B53/00 ,  C07C253/30 ,  C07C253/34 ,  C07C255/37 ,  C07C

CPC classification number: C07C253/34 ,  C07C255/37

公开(公告)号：CA2113973A1

公开(公告)日：1994-07-24

申请号：CA2113973

申请日：1994-01-21

Applicant: HOECHST AG

Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR

IPC: C07C51/08 ,  C07C63/70 ,  C07C253/14 ,  C07C253/30 ,  C07C255/50 ,  C07C255/49

Abstract: 2,3-Difluoro-6-nitrobenzonitrile and 2 chloro-5,6-di-fluorobenzonitrile, process for their preparation and their use for the preparation of 2,3,6 trifluorobenzoic acid The present invention describes the novel intermediates 2,3-difluoro-6-nitrobenzonitrile and 2-chloro-5,6-di-fluorobenzonitrile, a process for their preparation and their advantageous use for the preparation of 2,3,6trifluorobenzoic acid, which in turn is a valuable intermediate for the preparation of insecticides and antibacterial agents. The intermediates according to the invention are prepared from 2,3,4-trifluoronitrobenzene by fluorine/cyanide exchange and subsequent denitrating chlorination. 2,3,6-Trifluorobenzoic acid can be prepared from the novel intermediates, in a manner known per se in the literature, by simple chlorine/fluorine exchange and subsequent hydrolysis in a process which overall is industrially advantageous and economically favorable.

公开(公告)号：AU646563B2

公开(公告)日：1994-02-24

申请号：AU1706792

申请日：1992-05-21

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: C07C51/083 ,  C07C51/377 ,  C07C51/56 ,  C07C51/567 ,  C07C63/68 ,  C07D307/89

Abstract: Process for the preparation of 3,4,6-tetrafluorophthalic acid of the formula (1) (1) or the anhydride thereof in good yields and in an advantageous manner, by dehalogenating tetrafluorophthalic anhydride of the formula (2) (2) or tetrafluorophthalic acid in aqueous-alkaline medium using zinc at temperatures of approximately 20 DEG C. to approximately 160 DEG C. and, if appropriate, converting the resulting 3,4,6-trifluorophthalic acid into the anhydride in a known manner by dehydrating it.

公开(公告)号：CA2080208A1

公开(公告)日：1993-04-10

申请号：CA2080208

申请日：1992-10-08

Applicant: HOECHST AG

Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR ,  FORSTINGER KLAUS

IPC: C07C201/12 ,  C07C205/26 ,  C07C205/22

Abstract: HOE 91/F 318 Process for the preparation of 2-nitro-5-fluoro- or -5-chlorophenol The present invention relates to a process for the preparation of isomerically pure 2-nitro-5-fluoro- or -5-chlorophenol, by reacting 2,4-difluoronitrobenzene or 2,4-dichloronitrobenzene with aqueous alkali metal or alkaline earth metal hydroxide solution or suspension in the absence of organic solvents or other solubility promoting substances at temperatures from about 20.degree.C to about 190.degree.C, adjusting the pH of the reaction mixture to about 1 to about 6 by the addition of acid, steam distilling the resultant product and isolating it from the distillate after cooling.

公开(公告)号：CA2205671A1

公开(公告)日：1997-11-20

申请号：CA2205671

申请日：1997-05-16

Applicant: HOECHST AG

Inventor： PAPENFUHS THEODOR ,  PFIRMANN RALF

IPC: C07B61/00 ,  C07C67/11 ,  C07C69/76 ,  C07C227/18 ,  C07C229/54 ,  C07C319/20 ,  C07C323/62 ,  C07C67/08 ,  C07C67/31 ,  C07C229/60

Abstract: Process for the preparation of esters of aromatic carboxylic acids The present invention relates to a process for the preparation of compounds of the formula (1) R1R2R3R4R5ArCOOR (1) in which R1, R2, R3, R4 and R5 are identical or different and are hydrogen, a halogen, an alkyl or alkoxy group having 1 to 6 carbon atoms or OR, NHR, NR2, SR or COOR, in which R is an alkyl radical having 1 to 4 carbon atoms, Ar is an aryl radical having 6 to 12 carbon atoms and the radical R shown in formula (1) has the above meaning, by reacting a compound of the formula (2) R1R2R3R4R5ArCOOH (2) in which R1, R2, R3, R4 and R5 are identical or different and are hydrogen, a halogen, an alkyl or alkoxy group having 1 to 6 carbon atoms, OH, NH2, NHR, SH or COOH and Ar has the same meaning as in formula (1), with a sulfate of the formula (RO)2SO2, in which R has the above meaning, in the presence of a water-insoluble tertiary amine and water at a temperature of 10 to 120.degree.C in the presence or absence of a water-insoluble solvent and with the addition of a base, at a pH of 5 to 12.

公开(公告)号：IN177099B

公开(公告)日：1996-11-09

申请号：IN337CA1993

申请日：1993-06-17

Applicant: HOECHST AG

Inventor： PFIRMANN RALF ,  PAPENFUHS THEODOR

IPC: C07C63/15

公开(公告)号：CA2162344A1

公开(公告)日：1996-05-09

申请号：CA2162344

申请日：1995-11-07

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS ,  PFIRMANN RALF

IPC: C07B53/00 ,  C07C253/30 ,  C07C253/34 ,  C07C255/37

Abstract: The present invention relates to the compounds cis4-(2,2,3,3-tetrafluoropropoxy)cinnamonitrile and trans4-(2,2,3,3-tetrafluoropropoxy)cinnamonitrile and to a process for their preparation. The process relates to the preparationofcis-4-(2,2,3,3-tetrafluoropropoxy)cinnamo-nitrile and trans-4-(2,2,3,3-tetrafluoropropoxy)cinnamo-nitrile or optionally one of these two compounds, by fractionally distilling a mixture containing cis- and trans-4-(2,2,3,3-tetrafluoropropoxy)cinnamontrile under reduced pressure, separating off a main fraction containing at least 80% by weight of cis-4-(2,2,3,3-tetrafluoro-propoxy)cinnamonitrile and a main fraction containing at least 80% by weight of trans-4-(2,2,3,3-tetrafluoro-propoxy)cinnamonitrile, further purifying these main fractions by means of fractional crystallization or melt crystallization or adjusting one of these main fractions by isomerization to the cis/trans isomer ratio corresponding to the particular thermodynamic equilibrium and returning it to the process and returning the remaining fractions to the process directly or after isomerization.