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公开(公告)号:SE7713386A
公开(公告)日:1978-05-26
申请号:SE7713386
申请日:1977-11-25
Applicant: HOECHST AG
Inventor: BARTMANN W , LERCH U , TEUFEL H , SCHOLKENS B , BECK G
IPC: A61K31/205 , A61K31/22 , A61K31/557 , A61K31/5575 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/02 , C07D317/72 , C07D319/08 , C07D333/32 , C07D339/06 , C07D339/08 , C07D409/06 , C07F9/40 , C07C177/00
CPC classification number: C07F9/4018 , C07C405/00 , C07D339/06 , C07F9/4006
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公开(公告)号:SE7711509A
公开(公告)日:1978-04-17
申请号:SE7711509
申请日:1977-10-12
Applicant: HOECHST AG
Inventor: REUSCHLING K KUHLEIN D-B , LINKIES A , SCHOLKENS B
IPC: A61K31/215 , A61K31/20 , A61P1/04 , A61P1/16 , A61P7/02 , A61P9/12 , A61P15/00 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/93 , C07D307/935 , C07C177/00
CPC classification number: C07D307/93
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公开(公告)号:SE7708245A
公开(公告)日:1978-01-17
申请号:SE7708245
申请日:1977-07-15
Applicant: HOECHST AG
Inventor: BARTMANN W , LERCH U , TEUFEL H , SCHOLKENS B
IPC: A61K31/20 , A61K31/23 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D317/72 , C07D319/08 , C07D333/32 , C07D339/06 , C07D339/08 , C07F9/40 , C07C177/00
CPC classification number: C07D317/72 , C07C405/00 , C07D319/08 , C07D339/06 , C07F9/4006 , C07F9/4018
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公开(公告)号:SE7708244L
公开(公告)日:1978-01-17
申请号:SE7708244
申请日:1977-07-15
Applicant: HOECHST AG
Inventor: BARTMANN W , LERCH U , TEUFEL H , SCHOLKENS B , BECK G
IPC: C07D339/08 , A61K31/19 , A61K31/215 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D317/72 , C07D339/06 , C07C177/00
Abstract: What is disclosed are prostaglandin-analogous cyclopentane derivatives of the formula I wherein R1 is hydrogen or a linear or branched, saturated or unsaturated aliphatic or cycloaliphatic radical having from 1 to 8 carbon atoms, or an araliphatic radical having from 7 to 9 carbon atoms, or a physiologically tolerable metal, NH4 or substituted ammonium ion derived from a primary, secondary or tertiary amine; R2 is a linear or branched, saturated or unsaturated aliphatic hydrocarbon radical having from 1 to 8 carbon atoms; R3 is hydrogen or a R4CO group wherein R4 is a hydrogen atom or a linear or branched alkyl group having up to 10 carbon atoms; A is a saturated, linear or branched alkylene group having from 2 to 5 carbon atoms, and a process for the manufacture thereof.
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公开(公告)号:SE7705613A
公开(公告)日:1977-11-15
申请号:SE7705613
申请日:1977-05-13
Applicant: HOECHST AG
Inventor: REUSCHLING D-B , LINKIES A , KUHLEIN K , SCHOLKENS B
IPC: C07D207/27 , A61K31/40 , A61K31/4015 , A61P43/00 , C07D207/26
CPC classification number: C07D207/26
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公开(公告)号:NZ223383A
公开(公告)日:1990-01-29
申请号:NZ22338388
申请日:1988-02-02
Applicant: HOECHST AG
Inventor: ENGLERT H C , LANG H J , MANIA D , SCHOLKENS B
IPC: A61K31/40 , A61K31/4025 , A61K31/41 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/535 , A61K31/54 , A61P9/00 , A61P9/08 , A61P9/10 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D417/04 , C07D521/00 , A61K31/395 , A61K31/415 , A61K31/42 , A61K31/425 , A61K31/495 , A61K31/50 , A61K31/505 , A61K31/55
Abstract: 3,4-Dihydro-2H-benzo[b]pyrans of the formula I I are described, in which R1 is H, OH, (C1-C2)-alkoxy, (C1-C2)-alkyl or NR4R5, R4 and R5 being identical or different and representing H, (C1-C2)-alkyl or (C1-C3)-alkylcarbonyl, R2 and R3 are identical or different and are alkyl having 1-4 carbon atoms, Ar is an aromatic or heteroaromatic system which is unsubstituted or substituted, n is 1 or 2 and X is a (CH2)r chain which can be interrupted by a heteroatom O, S or NR6, R6 being H or (C1-C4)-alkyl and r being one of the numbers 2, 3, 4 or 5. Processes for the preparation of these compounds, their use and pharmaceutical products based on these compounds are also described.
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公开(公告)号:NZ223384A
公开(公告)日:1989-11-28
申请号:NZ22338488
申请日:1988-02-02
Applicant: HOECHST AG
Inventor: ENGLERT H C , LANG H-J , MANIA D , SCHOLKENS B , KLAUS E
IPC: A61K31/40 , A61K31/41 , A61K31/535 , A61K31/54 , C07D405/04 , C07D413/04 , C07D417/04 , A61K31/395 , A61K31/415 , A61K31/445 , A61K31/42 , A61K31/425 , A61K31/495 , A61K31/50 , A61K31/505
Abstract: N-Benzopyranyllactams of the formula I in which R' represents CN, NO2 or SOn-Ar; where n = 1 or 2, Ar represents an aromatic or heteroaromatic system which is unsubstituted or substituted and p represents 1 or 2, R represents H, OH, (C1-C2)-alkoxy, (C1-C2)-alkyl, halogen or NR R , where R and R are identical or different and represent H, (C1-C2)-alkyl or (C1-C2)-alkylcarbonyl, R and R are identical or different and represent alkyl having 1-4 C atoms, the abovementioned meanings of R and R can also be exchanged, X represents a chain (CH2)m, which is substituted by at least 1 and at most 2m-1 (C1-C2)-alkyl groups, and can also be interrupted by a heteroatom Y having the meaning O, NR or S and R denotes H or (C1-C4)-alkyl and m represents 2, 3 or 4, are described. They have hypotensive activity and/or ureter-relaxing activity.
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公开(公告)号:SE7800689L
公开(公告)日:1978-07-22
申请号:SE7800689
申请日:1978-01-19
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOLKENS B
IPC: C07D317/30 , A61K31/215 , A61K31/335 , A61K31/34 , A61K31/341 , A61K31/357 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/58 , C07C177/00
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公开(公告)号:SE7800688A
公开(公告)日:1978-07-22
申请号:SE7800688
申请日:1978-01-19
Applicant: HOECHST AG
Inventor: BARTMANN W , BECK G , LERCH U , TEUFEL H , SCHOLKENS B
IPC: C07D307/42 , A61K31/20 , A61K31/34 , A61K31/341 , A61P9/12 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07C177/00
CPC classification number: C07C405/00
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公开(公告)号:SE7713386L
公开(公告)日:1978-05-26
申请号:SE7713386
申请日:1977-11-25
Applicant: HOECHST AG
Inventor: BARTMANN W , LERCH U , TEUFEL H , SCHOLKENS B , BECK G
IPC: A61K31/205 , A61K31/22 , A61K31/557 , A61K31/5575 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D307/02 , C07D317/72 , C07D319/08 , C07D333/32 , C07D339/06 , C07D339/08 , C07D409/06 , C07F9/40 , C07C177/00
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