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11.发明专利
公开(公告)号：AU2002359851A8
公开(公告)日：2003-07-30
申请号：AU2002359851
申请日：2002-12-20
Applicant: IDEXX LAB INC
Inventor： KRAH EUGENE REGIS III , LAWTON ROBERT , GUO HONGLIANG , AIYAPPA ASHOK
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公开(公告)号：AU4044900A
公开(公告)日：2000-10-16
申请号：AU4044900
申请日：2000-03-30
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , MERMER BRION , FRANCOEUR GREG
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13.发明专利
公开(公告)号：AU2002251784B2
公开(公告)日：2006-09-14
申请号：AU2002251784
申请日：2002-01-16
Applicant: IDEXX LAB INC
Inventor： BARTOL BARBARA ANN , LAWTON ROBERT , MACHENRY PAUL SCOTT , O'CONNOR THOMAS PATRICK JR
IPC: G01N33/53 , G01N33/68 , C07K7/08 , C07K14/195 , C07K14/29 , C07K16/12 , C12P21/08 , G01N33/569
Abstract: The invention provides methods and compositions for the detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies and antibody fragments.
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14.发明专利
公开(公告)号：AU2002359851A1
公开(公告)日：2003-07-30
申请号：AU2002359851
申请日：2002-12-20
Applicant: IDEXX LAB INC
Inventor： KRAH EUGENE REGIS III , GUO HONGLIANG , AIYAPPA ASHOK , LAWTON ROBERT
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15.发明专利
公开(公告)号：CA2469833A1
公开(公告)日：2003-07-24
申请号：CA2469833
申请日：2002-12-20
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , KRAH EUGENE REGIS III , GUO HONGLIANG , AIYAPPA ASHOK
IPC: C12N15/09 , A61K39/395 , A61P37/08 , A61P43/00 , C07K16/18 , C07K16/42 , C07K19/00 , C07K16/00 , C12N15/00
Abstract: The present invention provides canine heavy chain and light chain (both .lambda. and .kappa.) variable domain nucleic acids and polypeptides. The present invention also provides caninized antibodies comprised of the presen t disclosed canine variable domain framework sequences and CDRs specific for a n antigen obtained from antibodies from other than canines (preferably mouse). The invention also provides methods of making caninized antibodies and using them. This disclosure specifically describes caninized antibodies that are useful in the treatment of canine allergy. The general process of caninizati on permits the development of useful therapeutics, which includes but is not limited to allergy, osteoarcomma's and lymphomma's.
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Patent Agency Ranking16.发明专利
公开(公告)号：CA2433394C
公开(公告)日：2013-09-10
申请号：CA2433394
申请日：2002-01-16
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , O'CONNOR THOMAS PATRICK JR , BARTOL BARBARA ANN , MACHENRY PAUL SCOTT
IPC: C07K7/08 , G01N33/53 , C07K14/195 , C07K14/29 , C07K16/12 , C12P21/08 , G01N33/569 , G01N33/68
Abstract: The invention provides methods and compositions for the detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies and antibody fragments.
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公开(公告)号：ES2324401T3
公开(公告)日：2009-08-06
申请号：ES02720810
申请日：2002-01-16
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , O'CONNOR THOMAS PATRICK JR , BARTOL BARBARA ANN , MACHENRY PAUL SCOTT
IPC: G01N33/53 , G01N33/68 , C07K7/08 , C07K14/195 , C07K14/29 , C07K16/12 , C12P21/08 , G01N33/569
Abstract: Un polipéptido aislado que consiste en la SEQ ID NO:1 y variantes de sustitución de aminoácidos de la SEQ ID NO:1 que se unen específicamente a un anticuerpo anti-P30-1 de Ehrlichia.
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18.发明专利
公开(公告)号：CA2469833C
公开(公告)日：2008-05-20
申请号：CA2469833
申请日：2002-12-20
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , KRAH EUGENE REGIS III , AIYAPPA ASHOK , GUO HONGLIANG
IPC: C12N15/09 , C12N15/13 , A61K39/395 , A61P37/08 , A61P43/00 , C07K16/00 , C07K16/18 , C07K16/42 , C07K16/46 , C07K19/00
Abstract: The present invention provides canine heavy chain and light chain (both .lambda. and .kappa.) variable domain nucleic acids and polypeptides. The present invention also provides caninized antibodies comprised of the presen t disclosed canine variable domain framework sequences and CDRs specific for a n antigen obtained from antibodies from other than canines (preferably mouse). The invention also provides methods of making caninized antibodies and using them. This disclosure specifically describes caninized antibodies that are useful in the treatment of canine allergy. The general process of caninizati on permits the development of useful therapeutics, which includes but is not limited to allergy, osteoarcomma's and lymphomma's.
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公开(公告)号：ES2234180T3
公开(公告)日：2005-06-16
申请号：ES99107035
申请日：1999-04-09
Applicant: IDEXX LAB INC
Inventor： LAWTON ROBERT , MERMER BRION , FRANCOEUR GREG
Abstract: LA INVENCION SE REFIERE A PROTEINAS DE UNION QUE SE UNEN ESPECIFICAMENTE A UN PEPTIDO AISLADO Y PURIFICADO QUE COMPRENDE UNA LEUCINA SITUADA A UNA DISTANCIA DE DOS ENLACES PEPTIDICO DE UN PAR TIROSINA - ARGININA. OTRAS PROTEINAS DE UNION DE LA INVENCION INCLUYEN AQUELLAS QUE SE UNEN ESPECIFICAMENTE A UN PEPTIDO AISLADO Y PURIFICADO CON LA SECUENCIA CISTEINA - HUECO HUECO - PROLINA - HISTIDINA - HUECO - HUECO - HUECO - CISTEINA, O CISTEINA - HUECO - PROLINA - HISTIDINA - HUECO - PROLINA HUECO - HUECO - CISTEINA.
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公开(公告)号：AU6401800A
公开(公告)日：2001-03-05
申请号：AU6401800
申请日：2000-08-09
Applicant: IDEXX LAB INC
Inventor： GUO HONGLIANG , LAWTON ROBERT , MERMER BRION , AIYAPPA ASHOK P
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