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    Evaluation method for active state of cranial nerve cell
    12.
    发明专利
    Evaluation method for active state of cranial nerve cell 审中-公开
    CRANIAL神经细胞活性状态的评估方法

    公开(公告)号：JP2007289469A

    公开(公告)日：2007-11-08

    申请号：JP2006121632

    申请日：2006-04-26

    Applicant: Hamano Life Science Research Foundation ,  Kao Corp ,  花王株式会社 ,  財団法人濱野生命科学研究財団

    Inventor： KAMINAMI MASAYUKI ,  ITO YUKIO ,  YADA YUKIHIRO ,  NAGASHIMA YOSHINAO ,  MITOBE HIROYUKI

    IPC: A61B5/055 ,  G01R33/28

    Abstract: PROBLEM TO BE SOLVED: To enable a brain functional activated area related to a task to be specified in such a manner that the task is applied to a subject while effectively suppressing physiological function change alone accompanying stresses, and measurement data of the brain function related to the task is accurately acquired by a simple and inexpensive constitution without applying a large burden on the subject. SOLUTION: This specifying method for the brain functional activated area enables delivery of a bio-active substance to the subject with a sensing stimulation or a brain function activating subject applied in a non-invasive brain functional examination method by a bio-functional measuring method. Then, the brain function activated area related to the sensing stimulation or the execution of the brain function activating subject, which makes an indicia of the change of an intracerebral blood flow, is specified. As the bio-active substance, cedrol is preferably used, and the cedrol is preferably inhaled at a concentration of 0.01 to 50 μg/L. Also, the cedrol is preferably volatilized from a volatilization device 15 being formed by using a non-magnetic material. COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：使得能够以如下方式指定与任务相关的脑功能激活区域：使任务应用于受试者，同时有效地抑制伴随应力的生理功能变化，以及大脑的测量数据 与该任务有关的功能通过简单廉价的结构被准确地获得，而不对该对象施加大的负担。 解决方案：用于脑功能激活区域的这种指定方法使得能够通过生物功能的非侵入性脑功能检查方法中的感测刺激或脑功能激活受试者将生物活性物质递送给受试者 测量方法。 然后，规定与感觉刺激相关的大脑功能激活区域或大脑功能激活对象的执行，这是脑内血流量变化的标记。 作为生物活性物质，优选使用雪松汁，优选以0.01〜50μg/ L的浓度吸入雪松汁。 此外，雪松膏优选通过使用非磁性材料形成的挥发装置15挥发。 版权所有（C）2008，JPO＆INPIT

    Pupil's light reaction measuring instrument for evaluating relax feeling
    13.
    发明专利
    Pupil's light reaction measuring instrument for evaluating relax feeling 有权
    PUPIL的光反应测量仪器评估放松感觉

    公开(公告)号：JP2005143684A

    公开(公告)日：2005-06-09

    申请号：JP2003383325

    申请日：2003-11-13

    Applicant: Kao Corp ,  花王株式会社

    Inventor： NAGASHIMA YOSHINAO ,  SADATE HIDETOSHI ,  YADA YUKIHIRO

    IPC: A61B3/10 ,  A61B3/11 ,  A61B5/16

    CPC classification number: A61B3/112 ,  A61B5/16

    Abstract: PROBLEM TO BE SOLVED: To provide a pupil's light reaction measuring instrument for evaluating relax feeling easily and used by a general healthy subject and objectively, highly precisely and easily evaluating the degrees of the stress and relax.
    SOLUTION: This pupil's light reaction measuring instrument 10 for evaluating the relax feeling is used when tracking the pupil's light reaction and evaluating the relax feeling. The instrument is provided with a three-dimensional mask part 11 worn on the face covering the part of the eyes; a pupil imaging means 12 and a light stimulating means 13 disposed oppositely to the eyeball of, at least, one eye in the inner side of the three-dimensional mask part 11; a control analysis means 14 connected to the pupil imaging means 12 and the light stimulating means 13, controlling them, recording images transmitted from the pupil imaging means 12, and computing and analyzing the miosis and the mydriasis of the pupil based on the taken images. The weight when wearing the three-dimensional mask part 11 including the pupil imaging means 12 and the light stimulating means 13 is 30-120 g.
    COPYRIGHT: (C)2005,JPO&NCIPI

    Abstract translation: 要解决的问题：提供一种瞳孔光反应测量仪器，用于容易地评估放松感觉并且被普通健康受试者使用，并且客观地，高度精确和容易地评估应力程度和放松。 解决方案：当跟踪瞳孔的光反应并评估放松感时，使用用于评估放松感觉的该光瞳的光反射测量仪10。 该仪器具有戴在覆盖眼睛部分的脸部上的三维面具部分11; 瞳孔成像装置12和与三维掩模部11的内侧的至少一只眼睛的眼球相对设置的光刺激装置13; 连接到瞳孔成像装置12和光刺激装置13的控制分析装置14，控制它们，记录从瞳孔成像装置12发送的图像，以及基于所拍摄的图像计算和分析瞳孔的瞳孔缩小和瞳孔扩大。 当佩戴包括瞳孔成像装置12和光刺激装置13的三维掩模部分11的重量为30-120g。 版权所有（C）2005，JPO＆NCIPI

    LIPID METABOLISM IMPROVER
    15.
    发明专利
    LIPID METABOLISM IMPROVER 失效

    公开(公告)号：JPS63198630A

    公开(公告)日：1988-08-17

    申请号：JP3123287

    申请日：1987-02-13

    Applicant: KAO CORP

    Inventor： MURATA SHOICHI ,  NAGASHIMA YOSHINAO ,  HARA KENJI ,  KAYANE SHIGETO ,  IMAMURA TAKASHI

    IPC: C07H11/04 ,  A61K31/70 ,  A61P3/08 ,  A61P3/14

    Abstract: PURPOSE:To obtain a lipid metabolism improver having immediate effects free from side effects, containing a calcium hexose phosphate as an active ingredient. CONSTITUTION:A calcium hexose phosphate (e.g. calcium glucose-1-phosphate) and, if necessary, a given carrier for preparation, excipient, etc., are pharmaceuti cally manufactured by a conventional procedure to give the aimed substance. The substance can be made into tablets, granules, capsule agents, oral adminis tration agent, etc. A dose is 0.1-20g, preferably 1-10g calculated as calcium hexose per person daily. Acute toxicity of mouse of calcium glucose-1-phosphate is >=15,000mg/kg and the substance is extremely safe. Since the substance extremely lowers concentration of serum cholesterol, the substance is effective as a preventive and remedy for myocardial infarction, ischemic heart disease and hypercholesterolemia.

    Brain fatigue relieving agent
    16.
    发明专利
    Brain fatigue relieving agent 审中-公开
    大脑疲劳消除剂

    公开(公告)号：JP2007297304A

    公开(公告)日：2007-11-15

    申请号：JP2006125027

    申请日：2006-04-28

    Applicant: Kao Corp ,  花王株式会社

    Inventor： SADATE HIDETOSHI ,  NAGASHIMA YOSHINAO ,  WATANABE TAKUYA

    IPC: A61K31/192 ,  A23L1/30 ,  A61K31/216 ,  A61K31/353 ,  A61P25/00 ,  A61P25/20 ,  A61P43/00

    Abstract: PROBLEM TO BE SOLVED: To provide an agent for relieving brain fatigue such as the lowering of numeric ability caused by brain fatigue. SOLUTION: The agent for relieving the fatigue of human brain comprises (a) one or more compounds selected from chlorogenic acids, caffeic acid, ferulic acid and their pharmacologically allowable salts and (b) proanthocyanidin. COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：提供减轻脑疲劳的药剂，例如降低由脑疲劳引起的数字能力。 解决方案：用于缓解人脑疲劳的药剂包括（a）一种或多种选自绿原酸，咖啡酸，阿魏酸及其药理学允许的盐和（b）原花色素的化合物。 版权所有（C）2008，JPO＆INPIT

    Steam heating instrument
    17.
    发明专利
    Steam heating instrument 有权
    蒸汽加热仪

    公开(公告)号：JP2006271962A

    公开(公告)日：2006-10-12

    申请号：JP2006058564

    申请日：2006-03-03

    Applicant: Kao Corp ,  花王株式会社

    Inventor： IGAKI MICHIHITO ,  NAGASHIMA YOSHINAO ,  ISHIKAWA SHUJI ,  YAMASHITA KAZUTAKA

    IPC: A61F7/08

    CPC classification number: A61F2007/0062

    Abstract: PROBLEM TO BE SOLVED: To provide a steam heating instrument for giving relaxation to a user.
    SOLUTION: The steam heating instrument includes a heating part, so as to supply steam which is generated from the heating part under a situation where the instrument is abutted on a body surface by holding a sheet between the heating part and the body surface. The sheet includes at least a ventilation part having the moisture permeability of 150-2,000g/(m
    2 ×24hr). The heating part of the steam heating instrument has a steam generating function of maximizing the evaporation amount of the steam per unit time in 0.5-25 minutes from the start of heat generation. It is preferable that the heating part of the steam heating instrument has the steam generating function of allowing the cumulative evaporation amount of the steam in 30 minutes from the start of heat generation to be the range of 0.1-0.5g per 1g of the heat generating part. The sheet is 0.05-1.5mm in total thickness, including a function of controlling the amount of air supply to the heat generating part and a function of transmitting the heat of the steam heating part to the body surface.
    COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种用于给用户放松的蒸汽加热仪器。 解决方案：蒸汽加热仪器包括加热部件，以便在仪器通过在加热部件和主体表面之间保持片材而将仪器抵靠在体表表面的情况下供应由加热部件产生的蒸汽 。 该片材至少具有透湿度为150-2,000g /（m 2 / SP>×24hr）的通风部件。 蒸汽加热装置的加热部件具有蒸发发生功能，其在从发热开始的0.5-25分钟内使单位时间内蒸汽的蒸发量达到最大。 蒸汽加热装置的加热部分优选具有允许从发热开始起30分钟内的蒸汽的累积蒸发量为每1g生热量为0.1-0.5g的蒸汽发生功能 部分。 片材的总厚度为0.05-1.5mm，包括控制向发热部件供应的空气量的功能和将蒸汽加热部件的热传递到体表的功能。 版权所有（C）2007，JPO＆INPIT

    BEAUTY METHOD
    18.
    发明专利
    BEAUTY METHOD 失效

    公开(公告)号：JPH11221260A

    公开(公告)日：1999-08-17

    申请号：JP2554498

    申请日：1998-02-06

    Applicant: KAO CORP

    Inventor： NAGASHIMA YOSHINAO ,  YADA YUKIHIRO ,  KATOU YUURI

    IPC: A61H7/00 ,  A61K8/44 ,  A61K8/67 ,  A61K8/81 ,  A61Q19/00

    Abstract: PROBLEM TO BE SOLVED: To enable to obtain large massage effect and larger beauty effect to be realized by massaging along the direction of corium strand. SOLUTION: When an upper arm part a is massaged, since the direction of corium fiber in the upper arm part a is around the arm as shown by arrow marks, a part from the elbow to the shoulder is massaged repeatedly rubbing in the direction around so as to rub up from the elbow to the shoulder. Same as for the fore arm part b, a part from the wrist to the elbow is massaged by rubbing in the direction around the arm so as to rub up from the wrist to the elbow. The femoral region c is massaged by repeatedly rubbing in the direction around the leg so as to rub up from the knee to the crotch for massaging. The crus part d is massaged by repeatedly rubbing a part from the ankle to the knee part in the direction around the leg. The abdominal part e is massaged by repeatedly rubbing in the direction around the abdominal part so as to rub up from the lower abdominal part to the pit of the stomach. The hip part is massaged by repeatedly rubbing in the direction around the waist so as to rub up from the lower hip part to the upper hip part.

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