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    Polymer coatings containing drug powder of controlled morphology
    12.
    发明专利
    Polymer coatings containing drug powder of controlled morphology 未知

    公开(公告)号：AU2006270221B2

    公开(公告)日：2012-01-19

    申请号：AU2006270221

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： TAYLOR DOUG ,  COLE MIKE ,  DEYOUNG JAMES ,  MCCLAIN JIM ,  SMOKE CLINT

    IPC: B05D3/00 ,  A61L2/00

    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

    Coatings containing multiple drugs
    14.
    发明专利
    Coatings containing multiple drugs 未知

    公开(公告)号：AU2007243268B2

    公开(公告)日：2013-06-13

    申请号：AU2007243268

    申请日：2007-04-26

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： COLE MIKE ,  MCCLAIN JIM ,  TAYLOR DOUG ,  SMOKE CLINT ,  DEYOUNG JAMES

    IPC: A61F13/00 ,  A61F2/00 ,  A61F2/06

    Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.

    Polymer coatings containing drug powder of controlled morphology
    15.
    发明专利
    Polymer coatings containing drug powder of controlled morphology 未知

    公开(公告)号：AU2006270221A1

    公开(公告)日：2007-01-25

    申请号：AU2006270221

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： TAYLOR DOUG ,  COLE MIKE ,  DEYOUNG JAMES ,  MCCLAIN JIM ,  SMOKE CLINT

    IPC: B05D3/00 ,  A61L2/00

    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

    STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN
    17.
    发明申请
    STENT WITH POLYMER COATING CONTAINING AMORPHOUS RAPAMYCIN 审中-公开
    含非晶形RAPAMYCIN的聚合物涂层支架

    公开(公告)号：WO2007011708A8

    公开(公告)日：2007-04-26

    申请号：PCT/US2006027322

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC ,  TAYLOR DOUG ,  DAYOUNG JAMES ,  MCCLAIN JIM

    Inventor： TAYLOR DOUG ,  DAYOUNG JAMES ,  MCCLAIN JIM

    IPC: A61F2/02

    CPC classification number: A61F2/86 ,  A61F2/07 ,  A61F2002/821 ,  A61F2240/002 ,  A61F2250/0067 ,  A61L31/022 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/216 ,  A61L2300/606 ,  A61L2420/08

    Abstract: A coated coronary stent, comprising: a stainless steel sent framework coated with a primer layer of Parylene C; and a rapamycin-polyrner coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially uniformly dispersed within the rapamycin-polymer coating.

    Abstract translation: 一种带涂层的冠状动脉支架，包括：涂有聚对二甲苯C的底层的不锈钢发送框架; 和布置在支架框架上的具有基本均匀厚度的雷帕霉素聚合物涂层，其中雷帕霉素聚合物涂层包含聚甲基丙烯酸丁酯（PBMA），聚乙烯 - 共聚乙酸乙烯酯（PEVA）和雷帕霉素，其中涂层中基本上所有的雷帕霉素 呈无定形形式且基本均匀地分散在雷帕霉素聚合物涂层内。

    SURGICAL SUTURES HAVING INCREASED STRENGTH
    18.
    发明申请
    SURGICAL SUTURES HAVING INCREASED STRENGTH 审中-公开
    具有增强强度的外科手术

    公开(公告)号：WO2008042909A3

    公开(公告)日：2008-08-07

    申请号：PCT/US2007080213

    申请日：2007-10-02

    Applicant: MICELL TECHNOLOGIES INC ,  MCCLAIN JIM

    Inventor： MCCLAIN JIM

    IPC: C08J3/205

    CPC classification number: A61L17/145 ,  A61L17/005 ,  A61L17/12 ,  A61L2300/00

    Abstract: The invention relates to increasing the strength of bio-absorbable surgical sutures. The invention allows for delayed bioabsorption of suture materials to allow maintenance of mechanical strength of the suture for example in 'barbed' form.

    Abstract translation: 本发明涉及提高生物吸收性外科缝合线的强度。 本发明允许缝合材料的延迟生物吸收以允许维持例如“倒刺”形式的缝合线的机械强度。

    DRUG/POLYMER COMPOSITE MATERIALS AND METHODS OF MAKING THE SAME
    20.
    发明申请
    DRUG/POLYMER COMPOSITE MATERIALS AND METHODS OF MAKING THE SAME 审中-公开
    药物/聚合物复合材料及其制备方法

    公开(公告)号：WO2007002238A3

    公开(公告)日：2007-05-10

    申请号：PCT/US2006024221

    申请日：2006-06-21

    Applicant: MICELL TECHNOLOGIES INC ,  MCCLAIN JIM ,  DEYOUNG JAMES

    Inventor： MCCLAIN JIM ,  DEYOUNG JAMES

    IPC: A61K9/00 ,  A61F13/00 ,  A61K9/20 ,  A61K9/48

    CPC classification number: A61K47/32 ,  A61K9/0024 ,  A61K9/1635 ,  A61K9/1694

    Abstract: A method of forming a drug/polymer composite material is carried out by combining a drug material with a polymer material under pressure in the presence of a densified gas solvent (e.g., carbon dioxide) to form the drug/polymer composite material. Drug/polymer composite materials and shaped articles (e.g., subcutaneous drug depots) which may be produced by a process are also described, along with methods of use thereof.

    Abstract translation: 形成药物/聚合物复合材料的方法通过在致密化的气体溶剂（例如二氧化碳）的存在下将药物材料与聚合物材料在压力下组合以形成药物/聚合物复合材料来进行。 还可以描述可以通过方法制备的药物/聚合物复合材料和成型制品（例如，皮下药物贮库）及其使用方法。

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