-
公开(公告)号：JP2012183441A
公开(公告)日：2012-09-27
申请号：JP2012151964
申请日：2012-07-06
Applicant: Micell Technologies Inc , ミセル テクノロジーズ、インコーポレイテッド
Inventor： TAYLOR DOUG , MCCLAIN JIM , SMOKE CLINT , COLE MIKE , DEYOUNG JAMES
CPC classification number: A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
Abstract: PROBLEM TO BE SOLVED: To provide an effective method for depositing inert polymers and pharmaceutical or biological agents onto a substrate, where the collection process is efficient, the coating produced is conformal, substantially defect-free and uniform, the composition of the coating can be regulated and the morphology and/or secondary structure of the pharmaceutical or biological agents can be controlled.SOLUTION: The method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate includes steps of: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto the substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming the coating; and sintering the coating under conditions that do not substantially modify the morphology of the pharmaceutical agent.
Abstract translation: 要解决的问题：为了提供将惰性聚合物和药物或生物试剂沉积到基材上的有效方法，其中收集过程是有效的，所生产的涂层是共形的，基本上无缺陷的和均匀的， 可以调节涂层，并且可以控制药物或生物制剂的形态和/或二级结构。 解决方案：将包含聚合物和药剂的涂层沉积在基材上的方法包括以下步骤：通过第一孔排出至少一种治疗上需要的干粉形式的药剂; 通过第二孔排出至少一种干粉形式的聚合物; 将聚合物和/或药物颗粒沉积到基底上，其中在基底和药物和/或聚合物颗粒之间保持电位，从而形成涂层; 并在不显着改变药剂形态的条件下烧结涂层。 版权所有（C）2012，JPO＆INPIT
-
公开(公告)号：JP2013099598A
公开(公告)日：2013-05-23
申请号：JP2013024508
申请日：2013-02-12
Applicant: Micell Technologies Inc , ミセル テクノロジーズ、インコーポレイテッド
Inventor： TAYLOR DOUG , MCCLAIN JIM , SMOKE CLINT , COLE MIKE , DEYOUNG JAMES
IPC: A61L31/00
CPC classification number: A61F2/82 , A61F2210/0076 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/426 , A61L2300/606 , A61L2300/63 , A61L2420/08 , Y10T428/264 , Y10T428/265 , Y10T428/31507 , Y10T428/31544 , Y10T428/31551 , Y10T428/31663 , Y10T428/31786 , Y10T428/31935 , Y10T428/31938
Abstract: PROBLEM TO BE SOLVED: To provide an efficient method which applies an inactive polymer and medical or biological agent to a substrate so that the collection process is efficient, the coating produced is superficially conformal, substantially defect-free and uniform, the composition of the coating can be regulated and the morphology and/or secondary structure of the pharmaceutical or biological agents can be controlled.SOLUTION: The coating includes a stent scaffold, rapamycin, and polymer. A coated coronary stent has crystalline rapamycin of at least 50%.
Abstract translation: 要解决的问题：为了提供一种将无活性聚合物和医用或生物试剂应用于基材使得收集过程有效的有效方法，所生产的涂层是表面上保形的，基本上无缺陷的和均匀的，组合物 可以调节涂层，并且可以控制药物或生物制剂的形态和/或二级结构。 解决方案：涂层包括支架支架，雷帕霉素和聚合物。 涂覆的冠状动脉支架具有至少50％的结晶雷帕霉素。 版权所有（C）2013，JPO＆INPIT
-
公开(公告)号：AU2011256902B2
公开(公告)日：2015-03-12
申请号：AU2011256902
申请日：2011-12-16
Applicant: MICELL TECHNOLOGIES INC
Inventor： TAYLOR CHARLES DOUGLAS , MCCLAIN JAMES B , SMOKE CLINT , COLE MICHAEL E , DEYOUNG JAMES
Abstract: C:\Documnsand Scuin\pSXD\LalSettins\Tcmp\DcsCorp\OCR\3AGEo IOCRdo-L2/620II A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate; wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent. 4-j 4-04 = ) I -j co0 xo: uit
-
公开(公告)号：PL1909973T3
公开(公告)日：2019-01-31
申请号：PL06787258
申请日：2006-07-14
Applicant: MICELL TECHNOLOGIES INC
Inventor： TAYLOR DOUG , MCCLAIN JIM , SMOKE CLINT , COLE MIKE , DEYOUNG JAMES
-
公开(公告)号：ES2691646T3
公开(公告)日：2018-11-28
申请号：ES06787258
申请日：2006-07-14
Applicant: MICELL TECHNOLOGIES INC
Inventor： TAYLOR DOUG , MCCLAIN JIM , SMOKE CLINT , COLE MIKE , DEYOUNG JAMES
Abstract: Una endoprótesis vascular coronaria revestida que comprende: un bastidor de endoprótesis vascular; y un revestimiento de fármaco-polímero inmunosupresor de macrólido en el que al menos un 50 % del fármaco está en forma cristalina.
-
Patent Agency Ranking
公开(公告)号：CA2650590C
公开(公告)日：2018-04-03
申请号：CA2650590
申请日：2007-04-26
Applicant: MICELL TECHNOLOGIES INC
Inventor： DEYOUNG JAMES , TAYLOR DOUG , MCCLAIN JIM , SMOKE CLINT , COLE MIKE
Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
-
公开(公告)号：CA2650590A1
公开(公告)日：2007-11-08
申请号：CA2650590
申请日：2007-04-26
Applicant: MICELL TECHNOLOGIES INC
Inventor： DEYOUNG JAMES , SMOKE CLINT , COLE MIKE , MCCLAIN JIM , TAYLOR DOUG
Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
-
公开(公告)号：AU2007243268A1
公开(公告)日：2007-11-08
申请号：AU2007243268
申请日：2007-04-26
Applicant: MICELL TECHNOLOGIES INC
Inventor： SMOKE CLINT , TAYLOR DOUG , COLE MIKE , MCCLAIN JIM , DEYOUNG JAMES
IPC: A61K9/14
Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
-
公开(公告)号：AU6104700A
公开(公告)日：2001-02-13
申请号：AU6104700
申请日：2000-07-17
Applicant: MICELL TECHNOLOGIES INC , LAUBACH BERNADETTE STOREY , LITAKER KARLA , DEYOUNG JAMES , STEWART GINA
Inventor： STOREY-LAUBACH BERNADETTE , LITAKER KARLA , DEYOUNG JAMES , STEWART GINA
Abstract: A method for dry-cleaning articles such as fabrics and clothing in carbon dioxide while concurrently applying a sizing agent to the articles comprises contacting an article to be cleaned with a liquid dry cleaning composition for a time sufficient to clean the fabric. The liquid dry-cleaning composition comprises a mixture of carbon dioxide, a surfactant, a sizing agent. An organic co-solvent is preferably included. After the contacting step, the article is separated from the liquid dry cleaning composition. The method is preferably carried out at ambient temperature. Preferred sizing agents are low molecular weight hydrocarbon resins. The surfactant is preferably one that does not contain a CO2-philic group. The organic co-solvent is preferably an alkane and has a flash point above 140° F.
-
公开(公告)号：AU2015203152B2
公开(公告)日：2017-01-05
申请号：AU2015203152
申请日：2015-06-12
Applicant: MICELL TECHNOLOGIES INC
Inventor： TAYLOR CHARLES DOUGLAS , MCCLAIN JAMES B , SMOKE CLINT , COLE MICHAEL E , DEYOUNG JAMES
Abstract: H: \xd\Interwoven\NRPortbl\DCC\SXD\7897863_1.doc-6/10/2015 A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate; wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent. CO, =3) LU i C/)3 hI xL 0'01 W uiI
-
-
-
-
-
-
-
-
-
Search Results
30
records
(took 0.025 seconds)
