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    Polymer coating containing drug powder of controlled morphology
    1.
    发明专利
    Polymer coating containing drug powder of controlled morphology 有权
    包含控制性形态药物的聚合物涂层

    公开(公告)号：JP2012183441A

    公开(公告)日：2012-09-27

    申请号：JP2012151964

    申请日：2012-07-06

    Applicant: Micell Technologies Inc ,  ミセル テクノロジーズ、インコーポレイテッド

    Inventor： TAYLOR DOUG ,  MCCLAIN JIM ,  SMOKE CLINT ,  COLE MIKE ,  DEYOUNG JAMES

    IPC: A61L15/00 ,  A61L27/00 ,  A61L29/00 ,  A61L31/00

    CPC classification number: A61F2/82 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/426 ,  A61L2300/606 ,  A61L2300/63 ,  A61L2420/08 ,  Y10T428/264 ,  Y10T428/265 ,  Y10T428/31507 ,  Y10T428/31544 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31786 ,  Y10T428/31935 ,  Y10T428/31938

    Abstract: PROBLEM TO BE SOLVED: To provide an effective method for depositing inert polymers and pharmaceutical or biological agents onto a substrate, where the collection process is efficient, the coating produced is conformal, substantially defect-free and uniform, the composition of the coating can be regulated and the morphology and/or secondary structure of the pharmaceutical or biological agents can be controlled.SOLUTION: The method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate includes steps of: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto the substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming the coating; and sintering the coating under conditions that do not substantially modify the morphology of the pharmaceutical agent.

    Abstract translation: 要解决的问题：为了提供将惰性聚合物和药物或生物试剂沉积到基材上的有效方法，其中收集过程是有效的，所生产的涂层是共形的，基本上无缺陷的和均匀的， 可以调节涂层，并且可以控制药物或生物制剂的形态和/或二级结构。 解决方案：将包含聚合物和药剂的涂层沉积在基材上的方法包括以下步骤：通过第一孔排出至少一种治疗上需要的干粉形式的药剂; 通过第二孔排出至少一种干粉形式的聚合物; 将聚合物和/或药物颗粒沉积到基底上，其中在基底和药物和/或聚合物颗粒之间保持电位，从而形成涂层; 并在不显着改变药剂形态的条件下烧结涂层。 版权所有（C）2012，JPO＆INPIT

    Polymer coatings containing drug powder of controlled morphology
    3.
    发明专利
    Polymer coatings containing drug powder of controlled morphology 未知

    公开(公告)号：AU2011256902B2

    公开(公告)日：2015-03-12

    申请号：AU2011256902

    申请日：2011-12-16

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： TAYLOR CHARLES DOUGLAS ,  MCCLAIN JAMES B ,  SMOKE CLINT ,  COLE MICHAEL E ,  DEYOUNG JAMES

    IPC: B05D3/00 ,  A61L2/00

    Abstract: C:\Documnsand Scuin\pSXD\LalSettins\Tcmp\DcsCorp\OCR\3AGEo IOCRdo-L2/620II A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate; wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent. 4-j 4-04 = ) I -j co0 xo: uit

    Coatings containing multiple drugs
    4.
    发明专利
    Coatings containing multiple drugs 未知

    公开(公告)号：AU2007243268B2

    公开(公告)日：2013-06-13

    申请号：AU2007243268

    申请日：2007-04-26

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： COLE MIKE ,  MCCLAIN JIM ,  TAYLOR DOUG ,  SMOKE CLINT ,  DEYOUNG JAMES

    IPC: A61F13/00 ,  A61F2/00 ,  A61F2/06

    Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.

    Polymer coatings containing drug powder of controlled morphology
    6.
    发明专利
    Polymer coatings containing drug powder of controlled morphology 未知

    公开(公告)号：AU2006270221A1

    公开(公告)日：2007-01-25

    申请号：AU2006270221

    申请日：2006-07-14

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： TAYLOR DOUG ,  COLE MIKE ,  DEYOUNG JAMES ,  MCCLAIN JIM ,  SMOKE CLINT

    IPC: B05D3/00 ,  A61L2/00

    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

    COATINGS CONTAINING MULTIPLE DRUGS
    10.
    发明专利
    COATINGS CONTAINING MULTIPLE DRUGS 未知

    公开(公告)号：CA2650590A1

    公开(公告)日：2007-11-08

    申请号：CA2650590

    申请日：2007-04-26

    Applicant: MICELL TECHNOLOGIES INC

    Inventor： DEYOUNG JAMES ,  SMOKE CLINT ,  COLE MIKE ,  MCCLAIN JIM ,  TAYLOR DOUG

    IPC: A61F13/00 ,  A61F2/00 ,  A61F2/06

    Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.

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