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公开(公告)号:CA2883874A1
公开(公告)日:2014-10-23
申请号:CA2883874
申请日:2014-04-18
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号:AU2020250255A1
公开(公告)日:2020-12-17
申请号:AU2020250255
申请日:2020-10-08
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号:AU2020250288A1
公开(公告)日:2020-11-05
申请号:AU2020250288
申请日:2020-10-09
Applicant: OCULEVE INC
Inventor: LOUDIN JAMES DONALD , FRANKE MANFRED , HAMILTON DANIEL N , DORAISWAMY ANAND , ACKERMANN DOUGLAS MICHAEL
IPC: A61N1/36
Abstract: CONTACT LENS FOR INCREASING TEAR PRODUCTION Abstract Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
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公开(公告)号:AU2017260237A1
公开(公告)日:2018-11-22
申请号:AU2017260237
申请日:2017-05-02
Applicant: OCULEVE INC
Inventor: FRANKE MANFRED , SENCHYNA DIANE MICHELLE , HAMILTON DANIEL N
IPC: A61N1/36
Abstract: Described here are devices, systems, and methods for treating meibomian gland disease and/or blepharitis by providing intranasal stimulation. Generally, the devices may deliver electrical stimulation to the nasal mucosa. Intranasal stimulation may unblock obstructed meibomian glands and increase the lipid content of tears, both acutely during stimulation and subsequent to intranasal stimulation. The methods may include an initial round of stimulation to unblock obstructed meibomian glands, and subsequent shorter rounds of stimulation to cause meibum secretion and maintain the open glands.
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公开(公告)号:AU2017204782B2
公开(公告)日:2018-11-15
申请号:AU2017204782
申请日:2017-07-12
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号:AU2017204782A1
公开(公告)日:2017-07-27
申请号:AU2017204782
申请日:2017-07-12
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号:HK1220934A1
公开(公告)日:2017-05-19
申请号:HK16108987
申请日:2016-07-27
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
IPC: A61N20060101
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公开(公告)号:AU2015203275B2
公开(公告)日:2017-04-13
申请号:AU2015203275
申请日:2015-06-16
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health. WO 2014/172693 PCT/US2014/034733 100-% 118 0 o142
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公开(公告)号:AU2014253754B2
公开(公告)日:2015-03-19
申请号:AU2014253754
申请日:2014-04-18
Applicant: OCULEVE INC
Inventor: ACKERMANN DOUGLAS MICHAEL , LOUDIN JAMES DONALD , WARDLE JOHN , BALDWIN JARREN ARMOND , HAMILTON DANIEL N , KUZMA JANUSZ , STIVERS CHRISTOPHER WILLIAM
Abstract: Described here are devices, systems, and methods for treating one or more conditions (such as dry eye) or improving ocular health by providing stimulation to nasal or sinus tissue. Generally, the devices may be handheld or implantable. In some variations, the handheld devices may have a stimulator body and a stimulator probe having one or more nasal insertion prongs. When the devices and systems are used to treat dry eye, nasal or sinus tissue may be stimulated to increase tear production, reduce the symptoms of dry eye, and/or improve ocular surface health.
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公开(公告)号:EP3209370A4
公开(公告)日:2018-05-30
申请号:EP15851950
申请日:2015-10-22
Applicant: OCULEVE INC
Inventor: LOUDIN JAMES DONALD , FRANKE MANFRED , HAMILTON DANIEL N , DORAISWAMY ANAND , ACKERMANN DOUGLAS MICHAEL
CPC classification number: A61N1/3787 , A61N1/36046 , A61N1/36121 , B29D11/00038 , B29D11/00826
Abstract: Described here are devices, systems, and methods for increasing tear production by stimulating the cornea, conjunctiva, and/or subconjunctiva. In some variations, the devices may be in the form of a contact lens. The contact lens may comprise a lens body and a stimulator chip, where the stimulator chip is embedded in the lens body. An external power source wirelessly transmits energy to the stimulator chip, where the stimulator chip may convert the energy to an electric waveform to stimulate the cornea, conjunctiva, and/or subconjunctiva. Stimulation may activate the lacrimal reflex to increase tear production. The devices and systems for increasing tear production may be used in methods of treating dry eye, reducing the symptoms of tired eye, increasing comfort for contact lens wearers, and extending the number of years a contact lens user can wear contacts. Also described are methods of manufacturing a contact lens.
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