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公开(公告)号:AU348062S
公开(公告)日:2013-04-16
申请号:AU201311101
申请日:2013-03-06
Applicant: UCB PHARMA SA
Abstract: Newness and distinctiveness reside in the shape and configuration of a design for an end piece as shown in in solid line said end piece being for a cassette device for administering medication. The cassette device shown in broken line is displayed for illustrative purpose only and does not form part of the claimed design.
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公开(公告)号:AU2011290581A1
公开(公告)日:2013-04-04
申请号:AU2011290581
申请日:2011-08-19
Applicant: UCB PHARMA SA
Inventor: HUMPHREYS DAVID PAUL , PETERS SHIRLEY JANE , ADAMS RALPH , HEADS JAMES
IPC: C07K16/00 , A61K39/395
Abstract: The present invention provides an antibody of the class IgG4 comprising at least one heavy chain which comprises a C
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公开(公告)号:SG187677A1
公开(公告)日:2013-03-28
申请号:SG2013007950
申请日:2011-08-19
Applicant: UCB PHARMA SA
Inventor: HUMPHREYS DAVID PAUL , PETERS SHIRLEY JANE , ADAMS RALPH , HEADS JAMES
Abstract: The present invention provides an antibody of the class IgG4 comprising at least one heavy chain which comprises a CH1 domain and a hinge region, wherein in each heavy chain: a. the inter-chain cysteine at position 127, numbered according to the Kabat numbering system, in the CH1 domain is substituted with another amino acid; and b. one or more of the amino acids positioned in the upper hinge region is substituted with cysteine.
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公开(公告)号:GB201301935D0
公开(公告)日:2013-03-20
申请号:GB201301935
申请日:2013-02-04
Applicant: UCB PHARMA SA , UNIV LEUVEN KATH
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公开(公告)号:AU2011284896A1
公开(公告)日:2013-01-24
申请号:AU2011284896
申请日:2011-07-26
Applicant: UCB PHARMA SA
Abstract: The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
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公开(公告)号:AU2007279092B2
公开(公告)日:2012-12-13
申请号:AU2007279092
申请日:2007-07-24
Applicant: UCB PHARMA SA
IPC: C07D207/14 , A61K31/395 , A61P33/00 , C07D211/72 , C07D223/12 , C07D267/10 , C07D281/06 , C07D401/12 , C07D403/12 , C07D417/12
Abstract: The present invention relates to novel analine derivatives and their use in therapy, in particular their use in the treatment of fungal infections.
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公开(公告)号:ES2390455T3
公开(公告)日:2012-11-13
申请号:ES04765134
申请日:2004-09-13
Applicant: UCB SA , UCB PHARMA SA
Inventor: SURTEES JOHN , LURQUIN FRANCOISE , DIOUF OUSMANE
IPC: C07D207/27 , C07D207/26 , C07D207/267 , C07D207/277
Abstract: Un procedimiento para la preparación de derivados de 2-oxo-1-pirrolidina de fórmula general (I), y sus sales, en la que : R1 es Ra o Rb; R3 y R4 son iguales o distintos y es cada uno, de forma independiente, hidrógeno, hidroxi, tiol, halógeno, ciano, carboxi, ácido sufónico, Ra, Rb, alquilsulfonilo, arilsulfonilo, alquilsulfinilo, arilsulfinilo, alquiltio, ariltio, alcoxi, ariloxi, sulfonamida, acilo, éster, amido, aciloxi, esteroxi o amidooxi; X es -CONR5R6, -COOR7 o -CN; R5, R6, R7 son iguales o distintos, y es cada uno, de forma independiente, hidrógeno, Ra o Rb; Ra es alquilo C1-20 o alquilo C1-20 sustituido con uno o más hidroxi, tiol, halógeno, ciano, carboxi, ácido sufónico, Rb, alquilsulfonilo, arilsulfonilo, alquilsulfinilo, arilsulfinilo, alquiltio, ariltio, alcoxi, ariloxi, sulfonamida, acilo, éster, amido, aciloxi, esteroxi y/o amidooxi; Rb es arilo, heteroarilo, heterocicloalquilo o los mismos sustituidos con uno o más Ra, hidroxi, tiol, halógeno, ciano, carboxi, ácido sufónico, arilo, alquilsulfonilo, arilsulfonilo, alquilsulfinilo, arilsulfinilo, alquiltio, ariltio, alcoxi, ariloxi, sulfonamida, heterocicloalquilo, heteroarilo, acilo, éster, amido, aciloxi, esteroxi y/o amidooxi; indicando el asterisco (*) un centro estereogénico que puede estar en una configuración R o S; que comprende la reacción de un derivado de furano de fórmula (II) o (III) en las que R2 y R2’ son iguales o distintos y cada es uno alquilo C1-10 o el mismo sustituido con arilo, con un compuesto de fórmula (IV) y con H2 en presencia de catalizador y un alcohol como disolvente.
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