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公开(公告)号：BG101835A
公开(公告)日：1998-05-29
申请号：BG10183597
申请日：1997-08-15
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , HOEFFKEN HANS W , HORNBERGER WILFRIED , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
IPC: A61K31/00 , A61K38/55 , A61P7/02 , C07D205/04 , C07D207/16 , C07D213/53 , C07D213/63 , C07D213/72 , C07D213/78 , C07D213/79 , C07D239/28 , C07D241/14 , C07D241/24 , C07D401/12 , C07K5/06 , C07K5/062 , C07K5/078 , A61K31/40 , A61K31/445 , A61K31/495
Abstract: The description relates to compounds of formulain which A, B, D, R' and R have the meanings given in thespecification. the compounds am suitable for the treatment ofdiseases The novel compounds are produced via compounds of theformula H2N-CH2.G-M in which G and M have the meanings given in4 claims
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公开(公告)号：SG49156A1
公开(公告)日：1998-05-18
申请号：SG1996006978
申请日：1994-11-25
Applicant: BASF AG
Inventor： ECKES PETER , HORNBERGER WILFRIED , SCHWEDEN JURGEN , SUBKOWSKI THOMAS
Abstract: PCT No. PCT/EP94/03901 Sec. 371 Date May 31, 1996 Sec. 102(e) Date May 31, 1996 PCT Filed Nov. 25, 1994 PCT Pub. No. WO95/15183 PCT Pub. Date Jun. 8, 1995The invention relates to novel hirudin conjugates formed from a hirudin and one or more lipophilic compounds, where the lipophilic compound has an octanol/water partition coefficient of more than 1.8 and is chemically linked to the hirudin, to the preparation thereof and to the use thereof.
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公开(公告)号：HUT77289A
公开(公告)日：1998-03-30
申请号：HU9702107
申请日：1995-11-25
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , HORNBERGER WILFRIED , HOEFFKEN HANS WOLFGANG , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
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公开(公告)号：CA2263344A1
公开(公告)日：1998-02-19
申请号：CA2263344
申请日：1997-07-29
Applicant: BASF AG
Inventor： BAUCKE DORIT , LANGE UDO , MACK HELMUT , HORNBERGER WILFRIED , HOEFFKEN HANS WOLFGANG , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
IPC: A61K31/40 , A61K31/44 , A61K38/00 , A61K38/05 , A61P1/18 , A61P7/02 , A61P11/02 , A61P11/06 , A61P17/00 , A61P19/02 , A61P29/00 , A61P43/00 , C07D207/22 , C07D211/78 , C07K5/00 , C07K5/02 , C07K5/083 , C07K5/062 , C07K5/065
Abstract: Disclosed are compounds having formula (I) wherein the radicals R, R1, R2, R3, R4, R5 and R6, as well as l, m, and n have the meaning indicated in the description, and the production of said compounds. The new compounds can be used to combat illness. Also described are compounds having formula (II) wherein the radicals R, R1, R2, R3, R4, R5 and R6, as well as l, m, and n have the meaning indicated in claim 1, and compounds having formula (III) wherein l and R have the meaning indicated in claim 1 and Y is an N protective group, or N-terminal protected or unprotected amino acid or represents H.
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公开(公告)号：NO973657L
公开(公告)日：1997-10-03
申请号：NO973657
申请日：1997-08-08
Applicant: BASF AG
Inventor： SEITZ WERNER , MACK HELMUT , ZIERKE THOMAS , BOEHM HANS-JOACHIM , HOEFFKEN HANS WOLFGANG , KOSER STEFAN , PFEIFFER THOMAS , HORNBERGER WILFRIED
Abstract: PCT No. PCT/EP96/00472 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 6, 1996 PCT Pub. No. WO96/24609 PCT Pub. Date Aug. 15, 1996Thrombin inhibitors of the formula where R1, A, B and D have the meaning indicated in the description, and intermediates for the preparation thereof are described. The compounds I are suitable for controlling diseases.
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Patent Agency Ranking
公开(公告)号：NO973657A
公开(公告)日：1997-10-03
申请号：NO973657
申请日：1997-08-08
Applicant: BASF AG
Inventor： SEITZ WERNER , MACK HELMUT , ZIERKE THOMAS , BOEHM HANS-JOACHIM , HOEFFKEN HANS WOLFGANG , KOSER STEFAN , PFEIFFER THOMAS , HORNBERGER WILFRIED
CPC classification number: C07K5/0812 , A61K38/00 , C07K5/06026 , C07K5/06034 , C07K5/0606 , C07K5/06078 , C07K5/06113 , C07K5/06191
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217.发明专利
公开(公告)号：MX9704050A
公开(公告)日：1997-08-30
申请号：MX9704050
申请日：1995-11-25
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , HOFFKEN HANS WOLFGANG , HORNBERGER WILFRIED , ZIERKE THOMAS
IPC: A61K38/00 , A61K38/05 , A61K38/55 , A61P7/02 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/072 , C07K5/087 , C07K05/06
Abstract: Se describen compuestos de la formula I (Ver Formula) en donde R1; A y B tiene los significados establecidos en la descripcion, así como la preparacion de los mismos. Los compuestos novedosos son adecuados para controlar enfermedades.
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公开(公告)号：ZA9601276B
公开(公告)日：1997-08-19
申请号：ZA9601276
申请日：1996-02-19
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
IPC: A61K20060101 , C07K20060101 , C12N20060101 , C07K , A61K , C12N
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公开(公告)号：NO973764D0
公开(公告)日：1997-08-15
申请号：NO973764
申请日：1997-08-15
Applicant: BASF AG
Inventor： BOEHM HANS-JOACHIM , HOEFFKEN HANS WOLFGANG , HORNBERGER WILFRIED , KOSER STEFAN , MACK HELMUT , PFEIFFER THOMAS , SEITZ WERNER , ZIERKE THOMAS
IPC: A61K31/00 , A61K38/55 , A61P7/02 , C07D205/04 , C07D207/16 , C07D213/53 , C07D213/63 , C07D213/72 , C07D213/78 , C07D213/79 , C07D239/28 , C07D241/14 , C07D241/24 , C07D401/12 , C07K5/06 , C07K5/062 , C07K5/078 , C07K
Abstract: The invention relates to a compound of the formula I: or a salt thereof with a physiologically tolerated acid, or stereoisomers thereof, wherein R 1 , R 2 , A, B, C and D have the meanings described in the specification.
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公开(公告)号：NO973657D0
公开(公告)日：1997-08-08
申请号：NO973657
申请日：1997-08-08
Applicant: BASF AG
Inventor： SEITZ WERNER , MACK HELMUT , ZIERKE THOMAS , BOEHM HANS-JOACHIM , HOEFFKEN HANS WOLFGANG , KOSER STEFAN , PFEIFFER THOMAS , HORNBERGER WILFRIED
Abstract: PCT No. PCT/EP96/00472 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 6, 1996 PCT Pub. No. WO96/24609 PCT Pub. Date Aug. 15, 1996Thrombin inhibitors of the formula where R1, A, B and D have the meaning indicated in the description, and intermediates for the preparation thereof are described. The compounds I are suitable for controlling diseases.
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