公开(公告)号：US20090123108A1

公开(公告)日：2009-05-14

申请号：US12251032

申请日：2008-10-14

Applicant: Tom Baehr-Jones ,  Michael J. Hochberg ,  Axel Scherer

Inventor： Tom Baehr-Jones ,  Michael J. Hochberg ,  Axel Scherer

IPC: G02F1/035

CPC classification number: G02F1/3515 ,  G02F1/3517 ,  G02F1/365 ,  G02F2201/063

Abstract: A single-photon absorption all-optical modulator, systems employing the same, and methods of making and using the same. An illustrative example is provided based on silicon semiconductor technology that employs rectangular waveguides. In some embodiments, it is observed that the waveguides operate with an absorption density of less than 1017 cm−1s−1mW−1 to provide a single-photon absorption operation mode.

Abstract translation: 单光子吸收全光调制器，采用其的系统及其制造和使用方法。 提供了基于采用矩形波导的硅半导体技术的说明性示例。 在一些实施例中，观察到波导以小于1017cm-1s-1mW-1的吸收密度进行操作以提供单光子吸收操作模式。

公开(公告)号：US07524459B2

公开(公告)日：2009-04-28

申请号：US10351294

申请日：2003-01-23

Applicant: Mark L. Adams ,  Stephen R. Quake ,  Axel Scherer

Inventor： Mark L. Adams ,  Stephen R. Quake ,  Axel Scherer

IPC: B01L3/00

CPC classification number: G01N21/6454 ,  B01L3/502715 ,  B01L2300/0654

Abstract: Techniques for integrating optoelectronic system and microfluidic system. An apparatus for optical analysis includes a detector system and a microfluidic system on the detector system. The apparatus is free from any lens system between the microfluidic system and the detector system. Methods of making such an apparatus and using such an apparatus are also disclosed.

Abstract translation: 集成光电系统和微流体系统的技术。 用于光学分析的装置包括检测器系统和检测器系统上的微流体系统。 该装置在微流体系统和检测器系统之间没有任何透镜系统。 还公开了制造这种装置和使用这种装置的方法。

公开(公告)号：US20090067773A1

公开(公告)日：2009-03-12

申请号：US11849981

申请日：2007-09-04

Applicant: William P. Krug ,  Jocelyn Y. Takayesu ,  Michael Hochberg ,  Thomas W. Baehr-Jones ,  Eric Y. Chan ,  Larry Dalton ,  Axel Scherer

Inventor： William P. Krug ,  Jocelyn Y. Takayesu ,  Michael Hochberg ,  Thomas W. Baehr-Jones ,  Eric Y. Chan ,  Larry Dalton ,  Axel Scherer

IPC: G02F1/295

CPC classification number: G02F1/3132 ,  G02B6/12007 ,  G02F1/065 ,  G02F2203/15 ,  G02F2203/585 ,  H04J14/021 ,  H04J14/0212 ,  H04J14/0219

Abstract: A system and method are disclosed for a rapidly tunable wavelength selective ring resonator. An embodiment of a voltage-tunable wavelength selective ring resonator includes a ring-shaped waveguide formed on a semiconductor substrate, an electro-optic cladding layer formed over the ring-shaped waveguide, and voltage applying means for applying a voltage across the electro-optic cladding layer. The ring-shaped waveguide is configured to propagate optical signals having predetermined resonant wavelengths, the electro-optic cladding layer has a voltage-controlled variable refractive index, and the means for applying is configured to apply a wavelength-specific control voltage to the electro-optic cladding layer. The wavelength-specific control voltage will shift or tune the predetermined resonant wavelengths for the ring-shaped waveguide.

Abstract translation: 公开了一种用于快速可调波长选择环谐振器的系统和方法。 电压可调波长选择性环形谐振器的实施例包括形成在半导体衬底上的环形波导，形成在环形波导上的电光包层，以及用于在电光上施加电压的电压施加装置 包层 环形波导被配置为传播具有预定谐振波长的光信号，电光包层具有​​电压控制的可变折射率，并且施加装置被配置为将波长特定的控制电压施加到电 - 光纤覆层。 波长特定的控制电压将移动或调谐环形波导的预定谐振波长。

公开(公告)号：US07480319B2

公开(公告)日：2009-01-20

申请号：US10967110

申请日：2004-10-15

Applicant: Axel Scherer

Inventor： Axel Scherer

IPC: H01S3/00

CPC classification number: G02F1/0126 ,  B82Y20/00 ,  G02B6/1225 ,  G02F3/00 ,  G02F2202/32

Abstract: Optical switches and logic devices comprising microstructure-doped nanocavity lasers are described. These switches and logic devices have gain and thus can be cascaded and integrated in a network or system such as for example on a chip. Exemplary switching elements switch the intensity, wavelength, or direction of the output. Exemplary logic devices include AND, OR, NAND, NOR, NOT, and XOR gates as well as flip-flops. Microfluidic sorting and delivery as well as optical tweezing and trapping may be employed to select and position a light emitter in a nanooptical cavity to form the nanolaser.

Abstract translation: 描述了包括微结构掺杂的纳米腔激光器的光开关和逻辑器件。 这些开关和逻辑器件具有增益，因此可以级联并集成在网络或系统中，例如在芯片上。 示例性的开关元件切换输出的强度，波长或方向。 示例性逻辑器件包括AND，OR，NAND，NOR，NOT和XOR门以及触发器。 可以使用微流控分选和输送以及光学镊子和捕获来选择和定位纳米光腔中的发光体以形成纳米激光。

公开(公告)号：US20080274493A1

公开(公告)日：2008-11-06

申请号：US12127720

申请日：2008-05-27

Applicant: Stephen R. Quake ,  Marc A. Unger ,  Hou-Pu Chou ,  Todd A. Thorsen ,  Axel Scherer

Inventor： Stephen R. Quake ,  Marc A. Unger ,  Hou-Pu Chou ,  Todd A. Thorsen ,  Axel Scherer

IPC: C12Q1/02 ,  B01J19/00 ,  G01N21/01 ,  G01N21/64 ,  G01N27/00 ,  G01K13/00 ,  C12M1/34

CPC classification number: G01N33/00 ,  B01D57/02 ,  B01D61/18 ,  B01D61/28 ,  B01D63/081 ,  B01D63/088 ,  B01D2313/08 ,  B01D2313/90 ,  B01F5/0646 ,  B01F5/0647 ,  B01F7/00 ,  B01F11/0071 ,  B01F13/0059 ,  B01F13/1013 ,  B01F13/1022 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502746 ,  B01L3/502761 ,  B01L2200/0631 ,  B01L2200/10 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2400/0415 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/0633 ,  B01L2400/0655 ,  B01L2400/082 ,  C12M23/16 ,  C12M41/46 ,  F04B43/043 ,  F16K99/0001 ,  F16K99/0009 ,  F16K99/0015 ,  F16K99/0046 ,  F16K99/0048 ,  F16K99/0051 ,  F16K99/0059 ,  F16K2099/0074 ,  F16K2099/008 ,  F16K2099/0084 ,  G01N15/06 ,  G01N27/44743 ,  G01N27/44791 ,  G01N33/5005 ,  G01N33/5008 ,  G01N33/56966 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.

Abstract translation: 本发明提供微流体装置及其使用方法。 特别地，本发明的微流体装置可用于进行各种测定和高通量筛选。 本发明的微流体装置包括弹性体部件并且包括主流动通道; 多个分支流动通道; 多个控制信道; 和多个阀。 优选地，每个阀包括控制通道中的一个和可响应于施加到控制通道的致动力而从阀或液流通道偏转进入或从其中缩回的弹性体段。

公开(公告)号：US20080210320A1

公开(公告)日：2008-09-04

申请号：US11934192

申请日：2007-11-02

Applicant: Marc A. Unger ,  Hou-Pu Chou ,  Todd A. Thorsen ,  Axel Scherer ,  Stephen R. Quake

Inventor： Marc A. Unger ,  Hou-Pu Chou ,  Todd A. Thorsen ,  Axel Scherer ,  Stephen R. Quake

IPC: F15C1/06

CPC classification number: B29C51/00 ,  B01L3/502707 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2300/0861 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2400/046 ,  B01L2400/0481 ,  B01L2400/0655 ,  B33Y80/00 ,  B81B5/00 ,  B81B2201/036 ,  B81B2201/054 ,  B81C1/00119 ,  B81C2201/019 ,  B81C2201/034 ,  C12Q1/6874 ,  F04B43/043 ,  F15C1/06 ,  F15C5/00 ,  F16K11/20 ,  F16K13/00 ,  F16K31/126 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0046 ,  F16K99/0048 ,  F16K99/0051 ,  F16K99/0059 ,  F16K2099/0074 ,  F16K2099/0076 ,  F16K2099/0078 ,  F16K2099/008 ,  F16K2099/0094 ,  Y10T137/0491 ,  Y10T137/0497 ,  Y10T137/2224 ,  Y10T137/87249 ,  Y10T156/10 ,  Y10T428/24479 ,  Y10T428/24744 ,  C12Q2535/125

Abstract: A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.

公开(公告)号：US07397987B2

公开(公告)日：2008-07-08

申请号：US11119380

申请日：2005-04-29

Applicant: Jeremy Witzens ,  Axel Scherer

Inventor： Jeremy Witzens ,  Axel Scherer

IPC: G02B6/34

CPC classification number: G02B6/4206 ,  G02B6/124 ,  G02B6/2706

Abstract: An apparatus and method for increasing efficiency of grating couplers are disclosed. The apparatus through the use of a defect or a reflective element allows coupling of light around a normal or nearly normal angle with a high efficiency. The method disclosed teaches how to increase the efficiency of a grating coupler through the use of a defect or a mirror. The apparatus and method can be of particular utility in the context of optical clocking implemented with a III-V chip flip-chip bonded on a CMOS chip.

Abstract translation: 公开了一种提高光栅耦合器效率的装置和方法。 通过使用缺陷或反射元件的装置允许以高效率将光围绕正常或几乎正常的角度耦合。 所公开的方法教导了如何通过使用缺陷或反射镜来提高光栅耦合器的效率。 该装置和方法可以在使用结合在CMOS芯片上的III-V芯片倒装芯片实现的光时钟的上下文中具有特别的用途。

公开(公告)号：US07348600B2

公开(公告)日：2008-03-25

申请号：US10687768

申请日：2003-10-20

Applicant: Yukio Narukawa ,  Isamu Niki ,  Axel Scherer ,  Koichi Okamoto ,  Yoichi Kawakami ,  Mitsuru Funato ,  Shigeo Fujita

Inventor： Yukio Narukawa ,  Isamu Niki ,  Axel Scherer ,  Koichi Okamoto ,  Yoichi Kawakami ,  Mitsuru Funato ,  Shigeo Fujita

IPC: H01L21/15

CPC classification number: H01L33/24 ,  B82Y20/00 ,  H01S5/0213 ,  H01S5/3202 ,  H01S5/3203 ,  H01S5/34333 ,  H01S2304/12

Abstract: The invention provides a nitride semiconductor light-emitting device comprising gallium nitride semiconductor layers formed on a heterogeneous substrate, wherein light emissions having different light emission wavelengths or different colors are given out of the same active layer. Recesses 106 are formed by etching in the first electrically conductive (n) type semiconductor layer 102 formed on a substrate with a buffer layer interposed between them. Each recess is exposed in plane orientations different from that of the major C plane. For instance, the plane orientation of the A plane is exposed. An active layer is grown and joined on the plane of this plane orientation, on the bottom of the recess and the C-plane upper surface of a non-recess portion. The second electrically conductive (p) type semiconductor layer is formed on the inner surface of the recess. With the active layer formed contiguously to the semiconductor layer in two or more plane orientations, a growth rate difference gives rise to a difference in the thickness across the quantum well (active layer), giving out light emissions having different light emission wavelength peaks or different colors.

Abstract translation: 本发明提供了一种氮化物半导体发光器件，其包括形成在异质衬底上的氮化镓半导体层，其中具有不同发光波长或不同颜色的发光具有相同的有源层。 凹槽106通过在衬底上形成的第一导电（n）型半导体层102中蚀刻形成，其中缓冲层位于它们之间。 每个凹槽以与主C平面不同的平面取向曝光。 例如，A平面的平面取向被暴露。 活性层生长并在该平面取向的平面上，在凹部的底部和非凹部的C面上表面上接合。 第二导电（p）型半导体层形成在凹部的内表面上。 由于活性层以两个或多个平面取向与半导体层连续形成，所以生长速率差导致量子阱（有源层）上的厚度差异，发出具有不同发光波长峰值或不同的发光波长峰值 颜色。

公开(公告)号：US20080044887A1

公开(公告)日：2008-02-21

申请号：US11880836

申请日：2007-07-23

Applicant: George Maltezos ,  Axel Scherer

Inventor： George Maltezos ,  Axel Scherer

IPC: C12M1/42 ,  C12N1/12

CPC classification number: C12N13/00 ,  B01J19/0093 ,  C02F1/30 ,  C02F3/327 ,  C02F3/348 ,  C10L1/026 ,  C12M21/02 ,  C12M23/06 ,  C12M23/16 ,  C12M31/04 ,  C12N1/12 ,  C12P3/00 ,  C12P7/6463 ,  C12P7/649 ,  Y02E50/13 ,  Y02W10/18 ,  Y02W10/37

Abstract: Methods and devices of performing reactions for which presence of light is desirable are provided. Biological or chemical materials such as algae are put in a chamber shaped as a meandering fluid channel. The algae can be combined with biomass such as human or animal waste and then subject to light, such as natural light or light coming from a LED, to produce fuel. Production of fuel can be optimized by controlling the height-to-width ratio of the channels

Abstract translation: 提供了需要进行光的存在的反应的方法和装置。 将诸如藻类的生物或化学材料置于作为曲折流体通道形成的室中。 藻类可以与诸如人或动物废物的生物质结合，然后经受来自LED的光，例如自然光或光，以产生燃料。 可以通过控制通道的高宽比来优化燃料的生产

公开(公告)号：US20080013092A1

公开(公告)日：2008-01-17

申请号：US11804112

申请日：2007-05-17

Applicant: George Maltezos ,  John Lee ,  Axel Scherer ,  Emil Kartalov

Inventor： George Maltezos ,  John Lee ,  Axel Scherer ,  Emil Kartalov

IPC: G01N21/25 ,  B01D63/00 ,  F15C1/06 ,  F15C5/00

CPC classification number: G01N21/6456 ,  G01N21/6452 ,  Y10T137/2224

Abstract: Microfluidic assay detectors and microfluidic assay detection methods are disclosed. A microfluidic chip is coupled to a light emitting device, emission filters and excitation filters. Excited fluorescent light is detected by a camera and a lens. The correspondent reading allows parallel detection of features such as antigens and biomarkers. A microfluidic filter and related methods are also disclosed. The filter can be used with on-chip fluid filtration such as whole blood filtration for microfluidic blood analysis. The filter is able to filter the necessary volume of fluid and in particular blood in an acceptable time frame.

Abstract translation: 公开了微流控测定检测器和微流控测定检测方法。 微流控芯片耦合到发光器件，发射滤光器和激发滤光器。 激发的荧光灯由相机和透镜检测。 通讯阅读允许并行检测抗原和生物标志物等特征。 还公开了微流体过滤器和相关方法。 过滤器可用于片上流体过滤，如全血过滤用于微流体血液分析。 过滤器能够在可接受的时间范围内过滤所需体积的流体，特别是血液。