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公开(公告)号:US11703449B2
公开(公告)日:2023-07-18
申请号:US17184704
申请日:2021-02-25
Applicant: THE WAVE TALK, INC.
Inventor: Young Dug Kim , Kyoung Man Cho
IPC: G01N21/47
CPC classification number: G01N21/47 , G01N2201/0231 , G01N2201/06113
Abstract: Provided is a microorganism detection apparatus including a body, a sample accommodator module provided in the body to accommodate a sample, a beam irradiation module for irradiating a beam to the sample, a sensor module for detecting speckles generated when the beam irradiated to the sample is scattered due to motion of bacteria or microorganisms included in the sample, and a controller for controlling the beam irradiated from the beam irradiation module, and storing and analyzing images detected by the sensor module, wherein the sample accommodator module includes a sample accommodation block having a sample hole capable of accommodating a container containing the sample, and a heater for supplying heat to the bacteria or microorganisms in the sample at a preset temperature.
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公开(公告)号:US11703447B2
公开(公告)日:2023-07-18
申请号:US16467935
申请日:2017-12-08
Applicant: EPPENDORF SE
Inventor: Philipp Abel , Andreas Graff
IPC: G01N21/35 , G01N21/3504 , C12M1/34 , G01N33/00 , G01N21/31
CPC classification number: G01N21/3504 , C12M41/34 , G01N33/004 , G01N2021/3125 , G01N2201/0231 , G01N2201/0238
Abstract: The invention relates to a measurement apparatus for measuring the concentration of a gaseous substance. The apparatus comprises a light source, a light sensor, and a housing comprising at least one first housing member having a low thermal conductivity. A light path is formed from said light source to said light sensor, wherein the light path passes through a measurement region within said housing. The light source is configured to emit light with a spectral distribution such that said light is absorbed by said gaseous substance. Said light sensor is configured to receive the light emitted by the light source after it has passed through the measurement region. The first housing member comprises a thermal shielding region facing said measurement region on its one side and said light sensor on its other side, and is configured to permit the passage of light.
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公开(公告)号:US20230168187A1
公开(公告)日:2023-06-01
申请号:US18101448
申请日:2023-01-25
Applicant: Nikira Labs Inc.
Inventor: Manish Gupta , Rupal Gupta
CPC classification number: G01N21/31 , G02B5/10 , G02B27/30 , G01N2201/0231 , G01N2201/06113 , G01N2201/0633 , G01N2201/0636
Abstract: An optical system for performing an absorption measurement of a medium sample includes a laser source configured to output a laser beam having a wavelength corresponding to an absorption region of interest; a ringdown cavity comprising a chamber configured to receive the medium sample, an input mirror at an input end, an output mirror at an output end, and an optical axis that extends through the centers of the input mirror and the output mirror; a coupling device configured to couple the laser beam through the input mirror into the chamber; and a detector optically coupled with the cavity, and configured to detect an intensity of light of the wavelength corresponding to the absorption region of interest that extends through the output mirror, wherein a cavity geometry of the cavity increases the re-entrant condition of the cavity relative to a conventional cavity comprised of two spherical mirrors.
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公开(公告)号:US20230152216A1
公开(公告)日:2023-05-18
申请号:US17989317
申请日:2022-11-17
Applicant: Si-Ware Systems
Inventor: Bassem Mortada , Yasser M. Sabry , Samir Abozyd
IPC: G01N21/31
CPC classification number: G01N21/31 , G01N2201/0231 , G01N2201/1211
Abstract: Aspects relate to on-line compensation of instrumental drifts in miniaturized spectrometers due to variations in environmental conditions and due to other sources of instrumental drift. The spectrometer may include a light modulator, a detector, and a processor. The spectrometer may further include a sensor configured to obtain a value of a condition contributing to instrumental drifts in the spectrometer. The processor may be configured to extract a set of correction parameters from a correction matrix associating a plurality of sets of correction parameters with sensor values based on the value and to apply the set of correction parameters to an output of the detector to produce a corrected spectrum of a sample under test. The correction matrix may be generated for the spectrometer or may be based on a global correction matrix fitted to the spectrometer.
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公开(公告)号:US10073028B2
公开(公告)日:2018-09-11
申请号:US14842642
申请日:2015-09-01
Applicant: SpectraSensors, Inc.
Inventor: Joshua Cohen , Nathan St. John , Alfred Feitisch
IPC: G01N21/01 , G01J3/02 , G02B7/02 , H01S3/131 , H01S5/00 , H01S3/00 , G01N21/27 , G02B7/00 , H01S5/068 , G01J3/42
CPC classification number: G01N21/01 , G01J3/0286 , G01J3/42 , G01N21/27 , G01N2201/0231 , G01N2201/0636 , G02B7/008 , G02B7/028 , H01S3/0071 , H01S3/1317 , H01S5/0071 , H01S5/06804
Abstract: An optical head assembly for use in a spectrometer is provided that is configured to characterize one or more constituents within a sample gas. The assembly includes a thermoelectric cooler (TEC) having a cold side on one end and a hot side on an opposite end, a cold plate in thermal communication with the cold side of the TEC, a hot block in thermal communication with the hot side of the TEC, a light source in thermal communication with the cold plate such that a change in temperature of the TEC causes one or more properties of the light source (e.g., wavelength, etc.) to change, and an optical element in thermal communication with the cold plate positioned to collimate light emitted by the light source through the sample gas (such that properties of the optical element vary based on a change in temperature of the TEC).
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公开(公告)号:US10006857B2
公开(公告)日:2018-06-26
申请号:US15005321
申请日:2016-01-25
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Dan Vadim Regelman
CPC classification number: G01N21/51 , G01N21/0303 , G01N2021/513 , G01N2201/0231 , G01N2201/0415
Abstract: An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.
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公开(公告)号:US20180135107A1
公开(公告)日:2018-05-17
申请号:US15870290
申请日:2018-01-12
Applicant: Takara Bio USA, Inc.
Inventor: Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC: C12Q1/686 , H01L27/144 , B01L3/00 , G01N21/01 , H01L31/18 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , C12Q1/6806
CPC classification number: C12Q1/686 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/0689 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B82Y30/00 , C12Q1/6806 , C12Q1/6844 , G01N21/01 , G01N21/0332 , G01N21/6408 , G01N21/6452 , G01N21/76 , G01N35/0099 , G01N2021/6417 , G01N2021/6484 , G01N2035/0405 , G01N2201/0231 , H01L27/1443 , H01L31/0203 , H01L31/02325 , H01L31/024 , H01L31/105 , H01L31/18 , C12Q2565/501
Abstract: The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号:US20180135106A1
公开(公告)日:2018-05-17
申请号:US15870247
申请日:2018-01-12
Applicant: Takara Bio USA, Inc.
Inventor: Victor Joseph , Amjad Huda , Alnoor Shivji , Jie Zhou
IPC: C12Q1/686 , H01L27/144 , B01L3/00 , G01N21/01 , H01L31/18 , H01L31/0203 , H01L31/0232 , H01L31/024 , H01L31/105 , C12Q1/6806
CPC classification number: C12Q1/686 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/0689 , B01L2300/044 , B01L2300/0636 , B01L2300/0654 , B01L2300/0819 , B01L2300/0829 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B82Y30/00 , C12Q1/6806 , C12Q1/6844 , G01N21/01 , G01N21/0332 , G01N21/6408 , G01N21/6452 , G01N21/76 , G01N35/0099 , G01N2021/6417 , G01N2021/6484 , G01N2035/0405 , G01N2201/0231 , H01L27/1443 , H01L31/0203 , H01L31/02325 , H01L31/024 , H01L31/105 , H01L31/18 , C12Q2565/501
Abstract: The present invention provides miniaturized instruments for conducting chemical reactions where control of the reaction temperature is desired or required. Specifically, this invention provides chips and optical systems for performing and monitoring temperature-dependent chemical reactions. The apparatus and methods embodied in the present invention are particularly useful for high-throughput and low-cost amplification of nucleic acids.
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公开(公告)号:US09835556B2
公开(公告)日:2017-12-05
申请号:US15366054
申请日:2016-12-01
Applicant: HORIBA, LTD.
Inventor: Takuya Ido , Yasushi Hirata , Toshiaki Nakagawa
CPC classification number: G01N21/55 , G01N21/3504 , G01N21/61 , G01N21/8507 , G01N33/0036 , G01N2021/158 , G01N2021/8514 , G01N2021/8578 , G01N2201/0231 , G01N2201/06113 , G01N2201/0636
Abstract: A gas analysis device includes a probe tube, a flange, an optical system member, and heaters. The probe tube includes an optical path through which measurement light is projected onto a prescribed measurement region of a sample gas flowing through a flue and/or is received from the measurement region. The flange is fixed to the outer periphery of the probe tube and is attached to a pipe side wall. The optical system member projects measurement light onto the sample gas S within the measurement region and/or receives measurement light from the measurement region. The heaters are disposed within the flange and heats the portion where the probe tube and flange are fixed to each other.
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公开(公告)号:US20170314990A1
公开(公告)日:2017-11-02
申请号:US15652458
申请日:2017-07-18
Applicant: H2Optx Inc.
Inventor: Rudolf J. Hofmeister , Donald A. Ice , Scott W. Tandy
IPC: G01J3/42 , B01D46/00 , G01N33/15 , G01N23/00 , G01N21/65 , G01N21/3577 , G01N21/3504 , G01N21/33 , G01N21/25 , G01N21/01 , G01N1/06 , G01J3/44 , G01J3/10 , G01J3/06 , G01J3/00 , B01D46/42 , G01N35/10
CPC classification number: G01J3/42 , B01D46/0002 , B01D46/42 , G01J3/00 , G01J3/0202 , G01J3/0205 , G01J3/0237 , G01J3/0267 , G01J3/0286 , G01J3/0291 , G01J3/06 , G01J3/10 , G01J3/2823 , G01J3/44 , G01N1/06 , G01N21/01 , G01N21/25 , G01N21/253 , G01N21/33 , G01N21/3504 , G01N21/3577 , G01N21/65 , G01N23/00 , G01N33/15 , G01N35/10 , G01N2021/0106 , G01N2201/0231
Abstract: In some aspects, a device for apportioning granular samples includes a sample feeder defining a conduit, the conduit including a first opening to receive the granular samples and a second opening. The device includes a shuttle operably coupled to the sample feeder to receive the granular samples from the conduit via the second opening. The shuttle is configured to apportion the granular samples to incrementally enter a sample chamber to be analyzed. The device includes an outlet conduit fluidly coupled to the sample chamber and configured to permit the sample chamber to be evacuated.
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