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公开(公告)号：KR1020080007035A
公开(公告)日：2008-01-17
申请号：KR1020060066567
申请日：2006-07-14
Applicant: (주)바이오액츠
IPC: C07C311/00 , C09B29/039
Abstract: An acidic dye compound having antimicrobial activity is provided to have a structure in which two aromatic rings are linked by a sulfonamide group, and exhibit good fastness characteristics and excellent antimicrobial properties. An acidic dye compound having antimicrobial activity has a structure represented by the following formula of B^1-Ar^1-SO2NH-Ar^2-B^2. An acidic dye composition having antimicrobial activity comprises at least one of the acidic dye compounds, and further at least one dye compound selected from the group consisting of C.I. Acid Red 337, C.I. Acid Blue 324, C.I. Acid Yellow 199, and C.I. Acid Orange 67. The composition exhibits antimicrobial activity against Staphylococcus aureus, Klebsiella pneumoniae, or both strains thereof.
Abstract translation: 提供具有抗微生物活性的酸性染料化合物以具有其中两个芳环通过磺酰胺基团连接的结构，并表现出良好的牢度特性和优异的抗菌性能。 具有抗微生物活性的酸性染料化合物具有由下式表示的结构：B 1 -Ar 1-SO 2 NH -Ar 2-B 2。 具有抗微生物活性的酸性染料组合物包含至少一种酸性染料化合物，以及至少一种选自C.I. 酸性红337，C.I。 酸性蓝324，C.I。 酸性黄199和C.I. 酸性橙67.组合物对金黄色葡萄球菌，肺炎克雷伯杆菌或其两种菌株表现出抗菌活性。
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公开(公告)号：KR100688310B1
公开(公告)日：2007-03-02
申请号：KR1020050080366
申请日：2005-08-30
Abstract: Provided is an azo-based metal complex reactive dye, which has advantages of both azo-based metal complex dyes and reactive dyes, and shows an improved sunlight fastness and a high fixation ratio. The azo-based metal complex reactive dye is represented by a formula of MxAyBz, wherein M represents a metal selected from the group consisting of Cr, Co, Fe, Cu and Ni; each of x and y represents 1 or 2, and z is 1, 2 or 3; A is selected from tridendate ligands represented by formulae 7-13; B represents H2O or is selected from tridendate ligands represented by the formulae 7-13; each of R1 and R2 is selected from the group consisting of -OH, -NH2, -COOH, -NHCOCH2COCH3 and -NH-(C6H5); and at least one of R3-R9 is -NHCOCHBrCH2Br or -NHCOCBr=CH2, and each of the remaining substituents of R3-R9 is selected from the group consisting of -H, -NH2, -SO3H, -OH, -COOH, -CH3, -OCH3, -NH-(C6H5), -NH-(C6H5)CH3, -NHSO2-(C6H5), -NHSO2-(C6H5)Cl, -NHSO2-(C6H5)COOH, -NHCOCH3, -NH2CH3, -SO2NH2, -NHSO2CH3, -N(CH3)2, -N(C2H5)2, -NO2, -NHCONH2, -CONH2, -N(C2H4OH)2 and -OC2H5.
Abstract translation: 本发明提供一种偶氮类金属络合物活性染料，其兼具偶氮类金属络合物染料和活性染料两者的优点，并且显示出改善的日光牢度和高固色率。 偶氮类金属络合物反应性染料由式M x A y B z表示，其中M表示选自Cr，Co，Fe，Cu和Ni的金属; x和y中的每一个代表1或2，并且z是1,2或3; A选自由式7-13表示的十三酸配体; B代表H 2 O或选自式7-13代表的十三配位体; R 1和R 2各自选自-OH，-NH 2，-COOH，-NHCOCH 2 COCH 3和-NH-（C 6 H 5）; 并且R3-R9中的至少一个是-NHCOCHBrCH2Br或-NHCOCBr = CH2，并且R3-R9的其余取代基中的每一个选自-H，-NH2，-SO3H，-OH，-COOH， - （C 6 H 5）CH 3，-NHSO 2 - （C 6 H 5）， - NHSO 2 - （C 6 H 5）Cl，-NHSO 2 - （C 6 H 5）COOH，-NHCOCH 3，-NH 2 CH 3， - -N（CH 2）5，-NO 2，-NHCONH 2，-CONH 2，-N（C 2 H 4 OH）2和-OC 2 H 5。
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公开(公告)号：KR101953819B1
公开(公告)日：2019-03-06
申请号：KR1020170178076
申请日：2017-12-22
Applicant: (주)바이오액츠
IPC: C07D403/06 , C07D403/12 , C12Q1/68 , A61K31/404 , A01N57/24
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Patent Agency Ranking
公开(公告)号：KR101921662B1
公开(公告)日：2018-11-23
申请号：KR1020170135623
申请日：2017-10-19
Applicant: (주)바이오액츠
IPC: C07D405/12 , C09K11/06 , G01N33/58 , C07D405/14
Abstract: 본발명의목적은형광강도, 상대양자효율, 표지율면에서우수하여조영제조성물로도이용될수 있는형광화합물, 이를이용한표지방법등을제공하고자한다. 본발명에따른형광화합물은형광강도, 상대양자효율, 표지율면에서우수하여타겟물질의표지및 염색에보다효과적으로활용될수 있다. 또한, 광학안정성이우수하여장시간의염색에도안정적형광을나타내며, 체내에투여시 축적되지않으면서도형광강도가우수하여종래의염료에비하여소량의사용에도염색및 체내영상화가용이하여경제적으로이용이가능하다.
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公开(公告)号：KR101908870B1
公开(公告)日：2018-10-16
申请号：KR1020170179023
申请日：2017-12-26
Applicant: (주)바이오액츠
Abstract: 본발명은검체의다제내성아시네토박터바우마니균(MRAB)의감염여부를판단하는진단키트에대한것으로서, 상기진단키트를이용하여 MRAB의감염여부를판단하는방법은 LAMP 반응후의발색변화를육안으로관측함으로써이루어지고, 상기발색변화는마그네슘농도변화에의한것으로써마그네슘이온에민감하게반응하는본 발명에서개발된특별한염료화합물을이용하여확인할수 있다. 본발명에있어서상기 MRAB DNA의증폭은고리매개등온증폭법(LAMP)을이용하고있어서, 본발명에서제공하는진단키트는언제어디서나편리하게사용할수 있고또한신속하게진단이가능하다는장점이있다.
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公开(公告)号：KR101877003B1
公开(公告)日：2018-07-12
申请号：KR1020160142241
申请日：2016-10-28
Applicant: (주)바이오액츠
IPC: G01N33/52 , G01N33/84 , C07D311/80 , C07D209/60 , C07D209/04
Abstract: 본발명은마그네슘이온선택적으로검출할수 있는 BAPTA 유도체및 이를이용한마그네슘정량화방법에관한것이다.
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公开(公告)号：KR1020170122654A
公开(公告)日：2017-11-06
申请号：KR1020170047199
申请日：2017-04-12
Applicant: (주)바이오액츠
Abstract: 본발명은하기 [화학식 1]로표시되는형광화합물및 그제조방법에관한것이다. [화학식 1]상기 [화학식 1]에서, X, Y, R, R, R및 n는각각명세서에정의한바와같다.
Abstract translation: 本发明涉及由下式（1）表示的荧光化合物及其制备方法。 其中X，Y，R，R，R和n分别如说明书中所定义。
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公开(公告)号：KR1020130017111A
公开(公告)日：2013-02-20
申请号：KR1020110079332
申请日：2011-08-10
Applicant: (주)바이오액츠
IPC: G01N33/58 , G01N33/52 , C07D403/06 , C07D493/10
Abstract: PURPOSE: A method for labeling a biomolecule using a dye compound with a vinyl sulfone group is provided to effectively handle a dye. CONSTITUTION: A method for labeling a biomolecule comprises: a step of dissolving a dye containing a vinyl sulfone group in a first solvent and preparing a dye solution; a step of dissolving the biomolecule in a second solvent and preparing a biomolecule solution; a step of mixing the dye solution and the biomolecule solution and reacting the mixture solution; and a step of collecting solvents from the mixture solution and re-dissolving, filtering and purifying the remains. The first solvent is water or a solvent diluted with water.
Abstract translation: 目的：提供使用具有乙烯基砜基团的染料化合物标记生物分子的方法以有效地处理染料。 构成：标记生物分子的方法包括：将含有乙烯基砜基的染料溶解在第一溶剂中并制备染料溶液的步骤; 将生物分子溶解在第二溶剂中并制备生物分子溶液的步骤; 混合染料溶液和生物分子溶液并使混合溶液反应的步骤; 以及从混合溶液中收集溶剂并重新溶解，过滤和净化残留物的步骤。 第一种溶剂是水或用水稀释的溶剂。
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