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21.发明公开
公开(公告)号：KR1020120113959A
公开(公告)日：2012-10-16
申请号：KR1020110031665
申请日：2011-04-06
Applicant: 주식회사 바이오리더스 , 충남대학교산학협력단 , 국민대학교산학협력단
CPC classification number: A61K49/126 , A61K49/1863 , A61K49/1872
Abstract: PURPOSE: A nanocomposite containing anionic and cationic polymers and a method for preparing the same are provided to generate synergistic effect of amplifying magnetic resonance signal. CONSTITUTION: A method for fabricating a nanoparticle composite in which a magnetic resonance nano contrast agent is encapsulated in a polymer composite comprises: a step of mixing a contrast agent-containing organic solvent solution with anionic polymer-containing organic solvent solution to prepare an anionic polymer/magnetic resonance imaging nano contrast composite; and a step of adding cationic polymers to the composite.
Abstract translation: 目的：提供含有阴离子和阳离子聚合物的纳米复合材料及其制备方法，以产生放大磁共振信号的协同效应。 构成：制造其中将磁共振纳米造影剂包封在聚合物复合材料中的纳米颗粒复合材料的方法包括：将含造影剂的有机溶剂溶液与含阴离子聚合物的有机溶剂溶液混合以制备阴离子聚合物的步骤 /磁共振成像纳米对比复合材料; 以及向复合物中加入阳离子聚合物的步骤。
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22.发明公开Ｌ형 폴리감마글루탐산을 생산하는 신규 미생물 바실러스 메가테리움 토하 및 이로부터 생산된 Ｌ형 폴리감마글루탐산 有权新型微生物生产L型聚氨基葡糖酸和L型聚氨基葡萄糖酸的新型微生物MOHATERIUM TOHA
公开(公告)号：KR1020120063025A
公开(公告)日：2012-06-15
申请号：KR1020100124020
申请日：2010-12-07
Applicant: 주식회사 바이오리더스 , 국민대학교산학협력단 , 한국생명공학연구원 , 충남대학교산학협력단
CPC classification number: C12R1/11 , A23L33/135 , A23L33/175 , A61K8/88 , A61K38/02 , A61K2800/10 , A61Q19/00 , C12N1/20 , C12P21/02
Abstract: PURPOSE: A novel microorganism which produces L-type poly gamma glutamic acid is provided to obtain the poly gamma glutamic acid used as a thickening agent, and biodegradable plastic solvent. CONSTITUTION: A novel microorganism, Bacillus megaterium Toha(KCTC 11752BP), produces L-type poly gamma glutamic acid. The strain is derived from a fermented food. The strain has 16S rDNA sequence of sequence number 1 and produces the poly gamma glutamic acid at low salinity. A probiotic composition contains Bacillus megaterium Toha (KCTC 11752BP) and the poly gamma glutamic acid.
Abstract translation: 目的：提供一种产生L-型polyγ谷氨酸的新型微生物，以获得用作增稠剂的聚γ谷氨酸和可生物降解的塑料溶剂。 构成：一种新型微生物，巨大芽孢杆菌Toha（KCTC 11752BP）产生L-型polyγ谷氨酸。 该菌株来自发酵食物。 该菌株具有序列号1的16S rDNA序列，并产生低盐度的多聚谷氨酸。 益生菌组合物含有巨大芽孢杆菌Toha（KCTC 11752BP）和聚γ谷氨酸。
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公开(公告)号：KR1020110101612A
公开(公告)日：2011-09-16
申请号：KR1020100020733
申请日：2010-03-09
Applicant: 한국외국어대학교 연구산학협력단 , 국민대학교산학협력단
CPC classification number: C12Q1/686 , C12Q1/04 , C12Q2537/143 , C12Q2600/16 , C12R1/085 , C12R1/445
Abstract: 본 발명은 주요 식품 위해 세균으로 인식되고 있는 세 가지 그람양성 식중독 세균인, 바실러스 세균(
Bacillus
cereus ), 포도상구균(
Stapylococcus
aureus ) 및 리스테리아 세균(
Listeria
monocytogenesis )의 유무를 시료에서 간편하게 탐지할 수 있는 올리고뉴클레오타이드 및 이의 용도에 관한 것이다.-
公开(公告)号：KR101471043B1
公开(公告)日：2014-12-09
申请号：KR1020090001510
申请日：2009-01-08
Applicant: 주식회사 바이오리더스 , 국민대학교산학협력단
CPC classification number: C12N15/746 , A61K39/12 , A61K2039/523 , A61K2039/542 , C12N2710/20034 , C12N2710/20045 , C12N2810/55
Abstract: 본발명에따른인간파필로마바이러스의항원단백질의표면발현용벡터로형질전환된재조합유산균및 이를이용한조성물은자궁경부암치료용백신으로활용하여경구또는질 부위에직접적용할수 있으므로매우경제적인효과가있다.
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25.发明授权
公开(公告)号：KR101398214B1
公开(公告)日：2014-05-23
申请号：KR1020110031665
申请日：2011-04-06
Applicant: 주식회사 바이오리더스 , 충남대학교산학협력단 , 국민대학교산학협력단
CPC classification number: A61K49/126 , A61K49/1863 , A61K49/1872
Abstract: 본 발명은 음이온성 및 양이온성 고분자를 함유하는 나노복합체 및 이의 제조방법에 관한 것으로, 생체친화성 고분자 물질인 폴리감마글루탐산(γ-PGA)과 키토산의 이온성 자기조립 성질을 이용하여 산화철 기반 나노입자를 γ-PGA/키토산 고분자 복합체 내부로 봉입하여 제조한 폴리감마글루탐산(γ-PGA)/키토산/망간산화철 나노입자의 복합체 및 이의 제조방법에 관한 것이다.
본 발명에 따른 음이온성 폴리감마글루탐산(γPGA)와 양이온성 키토산을 이용한 이온성 조립을 통해 산화철 기반 나노입자는 고분자 복합체 내부로 봉입하여 복합체 내부에 갇혀있는 산화철 기반 나노입자들이 서로간의 상호작용으로 인해 자기공명신호 증폭의 시너지효과를 유발하기 때문에, 하나의 입자로 존재할 때보다 뛰어난 조영 효과가 있는 특징이 있다.-
Patent Agency Ranking
公开(公告)号：KR101342642B1
公开(公告)日：2013-12-20
申请号：KR1020110123774
申请日：2011-11-24
Applicant: 주식회사 바이오리더스 , 국민대학교산학협력단
Abstract: 본발명은폴리감마글루탐산을함유하는튀김제품의도우조성물에관한것으로, 보다상세하게는, 튀김제품의도우조성물에폴리감마글루탐산또는그의염을유효량으로첨가시킴으로써유탕처리시 흡유를저감시키고, 체내칼슘흡수를촉진시키며, 식감과맛을유지시킬수 있는폴리감마글루탐산을함유하는튀김제품의도우조성물에관한것이다. 본발명에따른폴리감마글루탐산을함유하는튀김제품의도우조성물은폴리감마글루탐산또는그의염을유효량으로배합하여제조함으로써기존제품과비교시 유탕처리중 튀김의흡유를감소시킬뿐만아니라, 체내칼슘흡수를촉진시킬수 있고, 맛과식감의저하를최소화할수 있는효과가있어튀김의지방함량이감소되고맛과식감이향상되어다양한튀김제품의생산을가능케함으로써국민건강증진및 관련식품외식산업에유용한효과가있다.
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公开(公告)号：KR1020120138432A
公开(公告)日：2012-12-26
申请号：KR1020110057907
申请日：2011-06-15
Applicant: 조선대학교산학협력단 , 강원대학교산학협력단 , 주식회사 바이오리더스 , 국민대학교산학협력단
IPC: A23K20/195 , A23K1/18 , C07K19/00
CPC classification number: A23K20/147 , A23K50/60 , A23K50/75 , C07K19/00
Abstract: PURPOSE: A feed additive containing P5 peptide for replacing antibiotics, and a producing method thereof are provided to use the feed additive for weaned piglets or meat chicken. CONSTITUTION: A feed additive containing P5 peptide for replacing antibiotics contains 0.30-0.50 parts of antimicrobial P5 peptide by weight, 3,300-3,500 kcal/kg of energy, 21.0-23.0 parts of crude protein by weight, and 1.0-1.6 parts of lysine by weight. The feed additive is for feed of weaned piglets. 0.30-0.50 parts of feed additive by weight is mixed with the total amount of feed. [Reference numerals] (AA) Peptide; (BB) Amino acid sequence; (CC) Property; (DD) Parent peptide; (EE) CA-MA: C-terminal removal (HSAKKF); (FF) P1:N-terminal addition; (GG) P1:C-terminal addition; (HH) CA-MA: C-terminal removal and substitution; (II) CA-MA: substitution
Abstract translation: 目的：提供含有用于替代抗生素的P5肽的饲料添加剂及其制备方法，用于断奶仔猪或肉鸡的饲料添加剂。 构成：含有用于替代抗生素的P5肽的饲料添加剂含有重量为0.30-0.50份抗微生物P5肽，3,300-3,500千卡/ kg能量，粗蛋白质重量为21.0-23.0份，赖氨酸为1.0-1.6份 重量。 饲料添加剂用于饲喂断奶仔猪。 将0.30-0.50份饲料添加剂与饲料总量混合。 （AA）肽; （BB）氨基酸序列; （CC）财产; （DD）亲本肽; （EE）CA-MA：C-末端去除（HSAKKF）; （FF）P1：N-末端加成; （GG）P1：C-末端加成; （HH）CA-MA：C-末端去除和取代; （二）CA-MA：取代
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公开(公告)号：KR1020120053682A
公开(公告)日：2012-05-29
申请号：KR1020100114925
申请日：2010-11-18
Applicant: 충남대학교산학협력단 , 주식회사 바이오리더스 , 국민대학교산학협력단
CPC classification number: A61K49/0054 , A61K49/0034 , A61K49/0056 , G01N21/6428 , G01N21/6456
Abstract: PURPOSE: An optical imaging probe containing a conjugate of polygammaglutamic acid and optical imaging dyeing is provided to accurately sense the position of sentinel lymph node in real time without radiation contamination. CONSTITUTION: An optical imaging probe for sensing sentinel lymph node contains a conjugate of polygammaglutamic acid and optical imaging dye. The optical imaging dye is a fluorescence dye within near infrared ray or visible ray, The fluorescence dye within near infrared ray includes Alexa Fluor 647, Alexa Fluor 660, Alexa Fluor 680, Alexa Fluor 700, Alexa Fluor 780, cy5, cy5.5, cy7, indocyanine green(ICG), Cypate, ITCC, NIR820, NIR2, IRDye680, IRDye700, IRDye800, DiD, DiR, Cresy Violet, Nile Blue, Oxazine 750, and Rhodamine800. The fluorescence dye within visible ray includes Alexa Fluor 350, Alexa Fluor 488, Alexa Fluor 532, Alexa Fluor 568, Alexa Fluor 633, Alexa Fluor 647, cy2, cy3, cy3.5, Fluorescein (FITC), NBD, Nile Red, Rhodamine B, Tetramethylrhodamine (TRITC), and Texas Red.
Abstract translation: 目的：提供含有聚氨基丁酸和光学成像染色结合物的光学成像探针，以准确地感测前哨淋巴结的位置，无辐射污染。 构成：用于检测前哨淋巴结的光学成像探针含有聚马氨酸和光学成像染料的共轭物。 光学成像染料是近红外线或可见光线内的荧光染料。近红外线中的荧光染料包括Alexa Fluor 647，Alexa Fluor 660，Alexa Fluor 680，Alexa Fluor 700，Alexa Fluor 780，cy5，cy5.5， cy7，吲哚菁绿（ICG），Cypate，ITCC，NIR820，NIR2，IRDye680，IRDye700，IRDye800，DiD，DiR，Cresy Violet，Nile Blue，Oxazine 750和Rhodamine800。 可见光中的荧光染料包括Alexa Fluor 350，Alexa Fluor 488，Alexa Fluor 532，Alexa Fluor 568，Alexa Fluor 633，Alexa Fluor 647，cy2，cy3，cy3.5，荧光素（FITC），NBD，尼罗红，罗丹明 B，四甲基罗丹明（TRITC）和德克萨斯红。
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公开(公告)号：KR100954882B1
公开(公告)日：2010-04-28
申请号：KR1020090053845
申请日：2009-06-17
Applicant: 주식회사 바이오리더스 , 한국생명공학연구원 , 충북대학교 산학협력단 , 충남대학교산학협력단 , 국민대학교산학협력단
IPC: C12N1/20 , A61K35/744 , A23C9/12 , A23K1/16 , A23L33/00
CPC classification number: C12R1/01 , A23K10/18 , A23K50/75 , A61K35/744 , C12N1/20 , A23C9/12 , A23L33/00
Abstract: PURPOSE: A novel microorganism Weissella cibaria BLS13 is provided to ensure antiviral performance and use as a feed additive, a fermentation product, food, and a medicinal product. CONSTITUTION: A Weissella cibaria BLS13(KCTC11516BP) is isolated from Kimchi. An antiviral composition contains the Weissella cibaria BLS13(KCTC11516BP) or its culture liquid. A pharmaceutical composition for preventing an influenza infection contains KCTC11516BP or its culture liquid. The pharmaceutical composition is used in the form of a tablet, capsule, suppository, powder, gel, or liquid.
Abstract translation: 目的：提供一种新型微生物Weissella cibaria BLS13，以确保抗病毒性能和用作饲料添加剂，发酵产品，食品和药用产品。 构成：从泡菜泡菜中分离出一种贻贝BIS13（KCTC11516BP）。 抗病毒组合物含有We aria aria aria BLS13（KCTC11516BP）或其培养液。 用于预防流感感染的药物组合物含有KCTC11516BP或其培养液。 药物组合物以片剂，胶囊，栓剂，粉剂，凝胶或液体的形式使用。
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公开(公告)号：KR1020090124769A
公开(公告)日：2009-12-03
申请号：KR1020080051165
申请日：2008-05-30
Applicant: 한국외국어대학교 연구산학협력단 , 국민대학교산학협력단
Abstract: PURPOSE: A method for detecting bacteria causing food poisoning of fruit juice through real time PCR is provided to simply and quickly detect bacteria in fruit juice. CONSTITUTION: A method for detecting bacteria causing food poisoning of fruit juice comprises: a step of performing lysis of fruit juice through ultrasonic wave to prepare sample; a step of adding chelating resin to the sample then centrifuging; a step of purifying the sample through gel filtration column to prepare DNA template; a step of performing realtime PCR with prepared DNA template. The gel filtration column is sephadex column.
Abstract translation: 目的：通过实时PCR检测引起果汁食物中毒的细菌，简单快速地检测果汁中的细菌。 构成：用于检测导致果汁食物中毒的细菌的方法，包括：通过超声波进行果汁溶解以制备样品的步骤; 向样品中加入螯合树脂然后离心的步骤; 通过凝胶过滤柱纯化样品以制备DNA模板的步骤; 用制备的DNA模板进行实时PCR的步骤。 凝胶过滤柱是sephadex柱。
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