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公开(公告)号：KR100967813B1
公开(公告)日：2010-07-05
申请号：KR1020080025256
申请日：2008-03-19
Applicant: 대구한의대학교산학협력단
Abstract: 본 발명은 나복자 (
Raphani
semen ) 추출물을 유효성분으로 함유하는 고지혈증 또는 비만의 예방 및 치료용 조성물에 관한 것으로, 상세하게는 본 발명의 나복자 물 추출물은 생체 내 실험 (
in
vivo )을 통해 고지방 사료를 섭취한 실험동물의 체중, 난소 주위 지방의 중량, 혈중 지질함량, 혈중 렙틴 및 아디포넥틴 함량을 유의적으로 감소하였으므로, 상기 조성물은 고지혈증 또는 비만의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용할 수 있다.
나복자, 고지혈증, 비만-
公开(公告)号：KR1020090072850A
公开(公告)日：2009-07-02
申请号：KR1020070141083
申请日：2007-12-29
Applicant: 대구한의대학교산학협력단
IPC: A61K36/804 , A61P17/18 , A61P17/00
Abstract: A composition containing a Rehmannia glutimosa Libosch as an active ingredient is provided to have cell protection from UV, inhibition of apoptosis, and tyrosinase activation suppression. A composition of external skin preparation for antiaging, whitening or keratin removement comprises a Rehmannia gultimosa Libosch extract which has antioxidation effect as an active ingredient. The extract is obtained using water, low alcohol of C1-4 or its mixture solvent, hexane, butyleneglycol, propyleneglycol, glycerin, acetic acid ethyl, ether, and chloroform. The composition is used in a form of cream, gel, patch, spray, ointment, lotion, liniment, pasta or cataplasma. A cosmetic composition for anti-aging, whitening or keratin removement comprises the Rehmannia gultimosa Libosch extract.
Abstract translation: 提供含有地黄枸杞作为活性成分的组合物以具有免受UV的细胞保护，抑制凋亡和抑制酪氨酸酶活性。 用于抗衰老，美白或角质去除的外用皮肤制剂的组合物包含具有抗氧化作用作为活性成分的地黄杜鹃花提取物。 萃取液用C 1-4的低级醇或其混合溶剂，己烷，丁二醇，丙二醇，甘油，乙酸乙酯，乙醚和氯仿得到。 该组合物以霜剂，凝胶剂，贴剂，喷雾剂，软膏剂，洗剂，搽剂，面食或粘膜剂的形式使用。 用于抗衰老，美白或角蛋白去除的化妆品组合物包括地黄多菌提取物。
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公开(公告)号：KR100881368B1
公开(公告)日：2009-02-02
申请号：KR1020070108545
申请日：2007-10-26
Applicant: 대구한의대학교산학협력단
IPC: A61K36/8945 , A61K36/77 , A61K36/484 , A61P25/24
CPC classification number: A61K36/00 , A23L33/105 , A23V2200/31 , A23V2200/322 , A61K9/0053 , A61K36/484 , A61K36/725 , A61K36/77 , A61K36/8945 , A61K2236/33
Abstract: A pharmaceutical composition of preventing and treating powerfully depression is provided to have no side effect like addiction, sleepiness, chronic sleep failure and headache. A pharmaceutical composition of preventing and treating depression comprises extract from complex crude drug of Dioscorea batatas Decaisne, Euphoria longana STEUD, Glycyrrhiza uralensis FISCH, Zizyphi Fructus, Triticum aestivum L. and Zizyphi Spinosi Semen as an active ingredient. The extract is extract solubilized in a solvent selected from water including purified water, lower alcohol of C1 to C4 or their mixed solvent.
Abstract translation: 提供一种预防和治疗强力抑郁症的药物组合物，不会有成瘾，嗜睡，慢性睡眠障碍和头痛等副作用。 预防和治疗抑郁症的药物组合物包括从薯from蓉复合生药，玫瑰花蕙兰，甘草，枸杞子，紫菜，紫穗槐精油等作为活性成分提取物。 提取物溶解在选自包括纯水，C1至C4的低级醇或其混合溶剂的水的溶剂中。
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公开(公告)号：KR100723370B1
公开(公告)日：2007-05-30
申请号：KR1020050135707
申请日：2005-12-30
Applicant: 대구한의대학교산학협력단
Abstract: 본 발명은 피부 보습 및 항균효과가 있는 황금 및 황련 추출물을 유효성분으로 함유하는 화장료 조성물에 관한 것으로, 더욱 상세하게는 수상에 폴리올, 유상에 스테아릴 글리치네이트를 추가적으로 첨가하여 피부 자극이 최소화됨을 특징으로 하는 화장료 조성물에 관한 것으로 본원 발명은 무방부제 저자극 보습전용 화장료 조성물을 제공할 수 있다.
황금 추출물, 황련 추출물, 피부 보습, 항균, 화장료 조성물Abstract translation: 本发明的特征在于，所述金和黄连提取物与皮肤保湿和抗菌效果涉及含有一种化妆品组合物，作为活性成分，更具体地，进一步加入硬脂毛刺碳酸酯与多元醇，油奖励皮肤刺激最小化 并且本发明可以提供用于无刺激性，低刺激性，保湿和保湿条件的化妆品组合物。
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公开(公告)号：KR1020070024973A
公开(公告)日：2007-03-08
申请号：KR1020050080659
申请日：2005-08-31
Applicant: 대구한의대학교산학협력단
IPC: C12Q1/68
CPC classification number: C12Q1/683 , C12Q1/6827
Abstract: A kit for discriminating genetic identification among Cervus species through restriction fragment length polymorphism(RFLP) method is provided to supply accurate Cervus sample and be utilized for managing the quality of the Cervus. The method for discriminating genetic identification among Cervus species comprises the steps of: (a) extracting DNA from a Cervus sample; (b) preparing a reaction solution including the extracted DNA, a sense or an anti-sense primer; (c) amplifying the reaction solution; and (d) performing a RFLP on the amplified DNA to genotype it. The discrimination kit analyzes the genetic variation among Cervus species through the RFLP method including a PCR reagent containing a DNA extract reagent, a sense primer or an anti-sense primer and a restriction enzyme.
Abstract translation: 提供了一种通过限制性片段长度多态性（RFLP）方法鉴别鹿种的遗传鉴定的试剂盒，用于提供精确的鹿鹿样品，并用于管理鹿的品质。 用于区分种子遗传识别的方法包括以下步骤：（a）从鹿茸样品中提取DNA; （b）制备包括提取的DNA，有义或反义引物的反应溶液; （c）扩增反应溶液; 和（d）对扩增的DNA进行RFLP以对其进行基因型分析。 鉴别试剂盒通过包括DNA提取试剂，有义引物或反义引物和限制酶的PCR试剂在内的RFLP方法分析鹿茸种间的遗传变异。
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Patent Agency Ranking
公开(公告)号：KR100673070B1
公开(公告)日：2007-01-22
申请号：KR1020050080937
申请日：2005-08-31
Applicant: 대구한의대학교산학협력단
IPC: C12Q1/68
CPC classification number: C12Q1/6827 , C12Q1/686 , C12Q2561/113
Abstract: A method for discriminating genetic identification of ginseng species is provided to be able to supply accurate ginseng raw material through determination of the ginseng species, thereby being used for maintaining quality of the ginseng. The method comprises the steps of: (a) extracting DNA from ginseng sample; (b) method for preparing a reaction solution of primer consisting of the extracted DNA, sense primer(CCAAGTTGCA AACCCATGGT) and anti-sense primer(TTTGATTTCC TTGGCGCATT CC), VIC-primer(VIC-5'TTGGGTGGAT CTCGT-3-MGB) where TagMan MGB probe is attached at 3-terminal of the VIC primer, and FAM-primer(FAM-5'-TTGGGTGGCT CTCGT-3'-MGB) where TagMan MGB probe is attached at 3-terminal of the FAM-primer; (c) amplifying the reaction solution through PCR; (d) performing a real time PCR on the amplified DNA in combination and then analyzing it by comparing a DNA of Panax ginseng binding to the VIC primer obtained from the step(b) and having A nucleotide with a DNA of Panax quinquefolia binding to the FAM primer obtained from the step(b) and having C nucleotide through gene analysis shown in Fig. 1 using an SDS 7000 software so as to determine the Panax ginseng and the Panax quinquefolia.
Abstract translation: 提供了一种辨别人参物种遗传鉴定的方法，可以通过测定人参种类来提供准确的人参原料，从而保持人参的质量。 该方法包括以下步骤：（a）从人参样品中提取DNA; （b）制备由提取的DNA，有义引物（CCAAGTTGCA AACCCATGGT）和反义引物（TTTGATTTCC TTGGCGCATT CC），VIC引物（VIC-5'TTGGGTGGAT CTCGT-3-MGB）组成的引物的反应溶液的方法，其中 TagMan MGB探针连接在VIC引物的3个末端，以及FAM引物（FAM-5'-TTGGGTGGCT CTCGT-3-MGB），其中TagMan MGB探针连接在FAM引物的3个末端; （c）通过PCR扩增反应溶液; （d）组合对经扩增的DNA进行实时PCR，然后通过比较人参参与与步骤（b）获得的VIC引物结合的具有A核苷酸的DNA与DNA结合的Panax quinquefolia进行分析 从步骤（b）获得并具有图8所示的通过基因分析的C核苷酸的FAM引物。 1使用SDS 7000软件，以确定人参和Panax quinquefolia。
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公开(公告)号：KR1020070001402A
公开(公告)日：2007-01-04
申请号：KR1020050056867
申请日：2005-06-29
Applicant: 대구한의대학교산학협력단
IPC: C12Q1/68
CPC classification number: C12Q1/683 , C12Q1/6827
Abstract: A kit for genetically discriminating ginseng species by restriction fragment length polymorphism(RFLP) methods is provided to improve reproducibility and accuracy of discrimination, and evaluate relationship and genetic mutations among ginseng species. The kit for genetically discriminating ginseng species by restriction fragment length polymorphism(RFLP) methods comprises a DNA extracting reagent, a PCR reagent containing sense and antisense primers and restriction enzymes, wherein the sense primer has the nucleotide sequence of SEQ ID NO:1 and the antisense primer has the nucleotide sequence of SEQ ID NO:2; and the restriction enzymes include Sau3AI capable of recognizing the nucleotide sequence of SEQ ID NO:3. A method for genetically discriminating ginseng species comprises the steps of: extracting DNA from a ginseng sample; preparing the reaction solution containing extracted DNA and sense and antisense primers; PCR-amplifying the reaction solution; performing the RFLP method with the amplified DNA product.
Abstract translation: 提供了一种通过限制性片段长度多态性（RFLP）方法对人参进行遗传鉴定的试剂盒，以提高鉴别的重现性和准确性，并评估人参物种之间的关系和遗传突变。 通过限制性片段长度多态性（RFLP）方法用于遗传鉴别人参物种的试剂盒包括DNA提取试剂，含有义和反义引物和限制酶的PCR试剂，其中正义引物具有SEQ ID NO：1的核苷酸序列和 反义引物具有SEQ ID NO：2的核苷酸序列; 并且限制酶包括能识别SEQ ID NO：3的核苷酸序列的Sau3AI。 遗传上鉴别人参物种的方法包括以下步骤：从人参中提取DNA; 制备含有提取的DNA和有义和反义引物的反应溶液; PCR扩增反应溶液; 用扩增的DNA产物进行RFLP方法。
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公开(公告)号：KR100610313B1
公开(公告)日：2006-08-10
申请号：KR1020040063778
申请日：2004-08-13
Applicant: 대구한의대학교산학협력단
IPC: C12Q1/68
Abstract: 본 발명은 파이로시퀀싱(Pyrosequencing)법에 의한 목통의 종간 유전자 감별 키트에 관한 것으로써, 상세하게는 으름덩굴과 관목통을 파이로시퀀싱법에 의하여 유전자형을 분석하고, 목통의 종간 특이성 시퀀싱 프라이머를 고안하여 아케비아 종(Akebia species)과 아리스톨로키아 종(Aristolochia species)의 종간 연관성과 유전적 변이를 평가하기 위한 감별 키트에 관한 것이다. 본 발명의 감별 키트를 통하여 목통의 종을 판별함으로써 정확한 목통 원료를 공급할 수 있으며, 목통의 품질관리 방법으로 활용 할 수 있다.
으름덩굴, 관목통, 파이로시퀀싱(Pyrosequencing)법, 감별 키트-
公开(公告)号：KR101968837B1
公开(公告)日：2019-04-12
申请号：KR1020170126887
申请日：2017-09-29
Applicant: 대구한의대학교산학협력단
IPC: A61K36/28 , A61K31/34 , A23L33/105
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公开(公告)号：KR101898411B1
公开(公告)日：2018-09-12
申请号：KR1020180031910
申请日：2018-03-20
Applicant: 대구한의대학교산학협력단
IPC: A61K36/73 , A23L33/105
Abstract: 본발명은매괴화추출물을유효성분으로함유하는간질환의예방또는치료용조성물에관한것으로, 본발명의매괴화추출물은간세포손상시 증가하는형질전환성장인자베타1(TGF-β1)에의한 Smad 분자의인산화를억제하는효과가우수하고정상세포에독성을유발하지않는다는것을확인함으로써, 간질환치료제또는간질환예방을위한건강기능성식품의유효성분으로사용할수 있다.
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