Abstract:
PURPOSE: A drug delivery system is provided to selectively and easily allow bacteria to adhere onto a specific layer by comprising a hydrophilic biodegradable polymer layer and a hydrophobic biodegradable polymer layer. CONSTITUTION: A drug delivery system comprises a hydrophilic biodegradable polymer layer (100) and a hydrophobic biodegradable polymer layer (111). Bacteria adhere onto the surface of one layer among the biodegradable polymer layers. A drug is contained in the biodegradable polymer layer in which bacteria did not adhere. The hydrophilic biodegradable polymer contains one or more ingredients selected from alginate or a derivative thereof, chitosan or a derivative thereof, hyaluronic acid or a derivative thereof, gelatin, collagen, polyethylene glycol (PEG), and polyvinylpyrrolidone (PVP). The hydrophobic biodegradable polymer contains one or more ingredients selected from poly-caprolactone, L-poly-lactides (LPLA), poly-glycolic acid (PGA), poly-D-lactide (PDLA), poly-lactic acid (PLA), and poly-lactic-co-glycolic acid (PLGA). [Reference numerals] (100) Hydrophobic polymer layer; (110) Amphiphilic adhesive material; (111) Hydrophilic polymer layer containing a drug
Abstract:
본 발명은 신호 처리된 영상 정보를 받아 전기 신호로 변환해주는 주회로부, 주회로부의 정보를 받아 망막 전극을 직접 전기 신호로 자극하는 보조회로부로 구성된 고해상도 인공 망막 자극기에 관한 것이다. 이에 의해, 기존 고해상도 인공 망막 자극기가 가지고 있던 문제점들을 해결하여 고해상도 인공 망막 자극기의 효율적인 적용으로 인체 내 망막 삽입이 보다 용이하게 함으로써 시각 장애인들의 시각 확보의 질을 높이고 생활의 편의를 높이는데 기여할 수 있다.
Abstract:
PURPOSE: An artificial high resolution retina stimulator is provided to prevent damage to cells due to heat generation. CONSTITUTION: An artificial high resolution retina stimulator comprises a main circuit unit which receives signal-processed video information and converts the information into an electric signal, and a supplementary circuit unit which receives the information of the main circuit and stimulates a retina electrode with direct electric signal. One or more supplementary circuit unit shares the main circuit unit. In the supplementary circuit unit, a decoder and a microelectrode array are integrally formed. [Reference numerals] (AA) Signal-processed video information; (BB) N number of stimulators; (CC) Circuits for driving stimulator circuit; (DD) Main circuit unit; (EE) Artificial retina stimulating chip; (FF) Date(from main circuit unit); (GG) SEL(from decoder); (HH) Memory element; (II) Programmable electric signal generator; (JJ,N1,N2,N3,N4,N5,N6,N7,N8,N9) Electrode; (KK) N_xN number of microelectrode array; (LL) Decoder; (M1,M2,M3,M4,M5,M6,M7,M8,M9) Supplementary circuit unit; (OO) Retina electrode array+supplementary circuit unit+decoder; (PP) Need of at least(N+log_2N+2 Power Line) wires
Abstract:
본 발명은 표면에 미생물이 선택적으로 흡착된 이동성 마이크로 소자를 제작하는 방법으로서, 상기 마이크로 소자의 표면 에너지를 부분적 또는 전체적으로 조절하여 마이크로 소자에 흡착되는 미생물의 공간적 분포 또는 밀집도를 제어하는 것을 포함하는 방법 및 마이크로 소자의 표면 에너지 조절에 의해 제어된 공간적 분포 또는 밀집도로 흡착된 미생물을 포함하는 이동성 마이크로 소자에 관한 것이다. 본 발명에 따르면, 마이크로 소자의 표면 에너지를 조절하여 마이크로 소자에 흡착되는 미생물의 공간적 분포 또는 밀집도를 선택적으로 제어함으로써, 미생물의 운동성에 일관성을 부여하여 체내에서 마이크로 소자를 이동시키는 동력원으로 사용할 수 있게 함과 동시에, 마이크로 소자의 체내 투여를 가능하게 한다. 또한, 미생물 흡착을 위해 마이크로 소자의 표면에 추가적으로 화학적 처리하는 과정을 거치지 않고, 마이크로 소자의 표면 구성 물질이 나타내는 성질만으로 미생물이 선택적으로 흡착시켜 목적하는 이동성을 부여할 수 있다.
Abstract:
PURPOSE: A method for manufacturing a micro device in which microorganisms are selectively adsorbed on the surface is provided to selectively control the spatial distribution or close-packed state of the microorganisms. CONSTITUTION: A method for manufacturing a mobile micro device having microorganisms(120) selectively adsorbed on the surface comprises a step of partially or entirely controlling the surface energy of the micro device to control the spatial distribution or close-packed state of the microorganisms. The surface energy is controlled by varying the physical or chemical properties of the materials forming the micro device.
Abstract:
PURPOSE: A micro-patterned device and a method for compensating distortion of an optical coherent tomography image using the same are provided to be widely used for analyzing the result of experimental data and checking errors. CONSTITUTION: A micro-patterned device comprises a body(210) and micro patterns(200). The body is formed to be inserted into an organism. Micro patterns consist of a plurality of identifying areas(201,202). The identifying areas are formed on the surface of the body. The size of each identifying area is within 10 μm~100 μm. Each identifying area comprises a protrusion or a depression. The device comprises a metallic material on each identifying area and an organism-compatible material coated on the metallic material.
Abstract:
PURPOSE: An integrated apparatus for automatically generating and classifying droplets is provided to stores classified droplets by automatically droplets according to the mass, size, and composition ratio through the droplet control fluid of a droplet separator. CONSTITUTION: A droplet generator includes a droplet raw material supply unit(110,111,120,121), a droplet generation inducer(200), and a central path(100) and generates droplets by combining one or more droplet raw materials. A droplet classifier classifies the droplet according to weight, size, or composition ratio by using a flow structure or flow of droplet control fluid. The droplet generator is spatially connected to the droplet classifier.