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公开(公告)号：KR101590246B1
公开(公告)日：2016-02-01
申请号：KR1020140005880
申请日：2014-01-17
Applicant: 성균관대학교산학협력단
Abstract: 본발명은나노바이오하이브리드촉매의기능을향상시키기위한방법에관한것으로, 더욱구체적으로는나노바이오하이브리드촉매를담체에고정화하여복합체를제조하고, 상기복합체에고주파를가함으로써나노바이오하이브리드촉매의기능을향상시키는방법및 상기방법에의해제조된나노바이오하이브리드촉매에관한것이다. 본발명의방법에따라무기나노입자와효소가결합된나노바이오하이브리드촉매를담체에고정화하면촉매의촉매능, 열안정성, pH 내성, 유기용매내에서의활성및 재사용능을향상시킬수 있다. 또한, 고정화된나노바이오하이브리드촉매가포함된반응액에고주파(RF)를인가하면상기촉매의촉매기능을크게향상시킬수 있는효과가있다.
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公开(公告)号：KR101539205B1
公开(公告)日：2015-07-24
申请号：KR1020150056693
申请日：2015-04-22
Applicant: 성균관대학교산학협력단
Abstract: 본발명은세쿠리닌(securinine)을유효성분으로포함하는암 줄기세포분화유도용조성물및 이를이용한암 줄기세포분화유도방법에관한것으로, 구체적으로, 본발명은세쿠리닌(securinine)이암 줄기세포의분화를유도하고, 암세포내 암줄기세포를선택적으로사멸시킬수 있는효과가있음을밝히고이를통해본 발명의조성물이암 줄기세포의존재가알려진다양한암 종의분화유도에적용가능하고, 단독으로혹은기존의항암제와병행사용하여암의전이또는재발을효과적으로억제할수 있음을확인하였으며, 따라서암 질환에대한치료및 예방에유용하게이용될수 있다.
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公开(公告)号：KR101465354B1
公开(公告)日：2014-11-25
申请号：KR1020130087019
申请日：2013-07-23
Applicant: 성균관대학교산학협력단
IPC: C12N5/071 , C12N5/02 , C07K14/195
Abstract: 본 발명은 SKP(Seventeen kilodaltone protein) 단백질을 유효성분을 포함하는 줄기세포 분화 유도용 조성물 및 이를 이용한 줄기세포 분화 유도 방법에 관한 것으로, 기존의 줄기세포 분화 촉진제를 사용하지 않고 줄기세포의 분화를 유도할 수 있을 뿐만 아니라, 외배엽 세포, 중배엽 세포, 내배엽 세포, 신경 세포, 심근 세포 등 다양한 세포로의 분화가 가능하기 때문에, SKP 단백질을 이용한 다양한 배양조건을 확립한다면 다양한 세포로의 분화를 가능하게 할 것으로 기대되며, 이를 이용하여 줄기세포치료제, 암치료제 등 다양한 분야에 적용가능할 것으로 기대된다.
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公开(公告)号：KR1020140111872A
公开(公告)日：2014-09-22
申请号：KR1020130026333
申请日：2013-03-12
Applicant: 삼성전자주식회사 , 성균관대학교산학협력단
Abstract: The present invention relates to a method for scheduling in a device-to-device (D2D) communications system. The method for scheduling a link of a terminal in the D2D communications system includes the steps of: collecting information to show an medium access state of at least one adjacent link at a preset period; determining at least one link estimated to actually access a medium in a corresponding traffic slot among links with higher priority than the terminal based on the collected information, when the medium access state of the terminal is determined; and determining the medium access state of the terminal by considering at least one link estimated to actually access the medium.
Abstract translation: 本发明涉及一种在设备到设备（D2D）通信系统中进行调度的方法。 用于调度D2D通信系统中的终端的链路的方法包括以下步骤：收集信息以在预设周期内显示至少一个相邻链路的媒体接入状态; 当确定所述终端的介质访问状态时，基于所收集的信息，确定估计到实际访问对应业务时隙中的媒体的至少一个链路，所述链路优先于所述终端优先级高的链路; 以及通过考虑估计为实际访问所述介质的至少一个链路来确定所述终端的介质访问状态。
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公开(公告)号：KR1020140061278A
公开(公告)日：2014-05-21
申请号：KR1020130137241
申请日：2013-11-12
Applicant: 성균관대학교산학협력단
IPC: H01G11/36
CPC classification number: Y02E60/13 , H01G11/36 , C01B32/182 , H01G11/30
Abstract: The present invention relates to a biomolecular-capacitor using a protein outer cover-metal nanoparticle compound which is a bio-inorganic compound. The biomolecular-capacitor according to the present invention is applied to various fields such as a biochip, a biosensor, a bio electronic device, a next generation electric vehicle, and a smartphone by obtaining a fast capacitive time constant, high capacitance, and biocompatibility.
Abstract translation: 本发明涉及使用作为生物无机化合物的蛋白质外覆盖金属纳米粒子化合物的生物分子电容器。 根据本发明的生物分子电容器通过获得快速电容时间常数，高电容和生物相容性，被应用于诸如生物芯片，生物传感器，生物电子器件，下一代电动车辆和智能手机的各种领域。
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Patent Agency Ranking
公开(公告)号：KR1020140061277A
公开(公告)日：2014-05-21
申请号：KR1020130137240
申请日：2013-11-12
Applicant: 성균관대학교산학협력단
Abstract: The present invention relates to a composition comprising securinine as an active ingredient for inducing differentiation of a cancer stem cell and a method for inducing differentiation of a cancer stem cell by using the same. More specifically, the present invention reveals that the securinine incudes differentiation of the cancer stem cell and can selectively destroy the cancer stem cell in cancer cells. The composition of the present invention can be applied for inducing differentiation of a variety of cancer species which is known to have cancer stem cells, and can effectively suppress recurrence and metastasis of cancer by using the composition alone or combined with a conventional anticancer agent; thereby can be used for treating and preventing cancer diseases.
Abstract translation: 本发明涉及一种组合物，其包含作为诱导癌症干细胞分化的活性成分的硫嘌呤，以及通过使用该组合物诱导癌症干细胞分化的方法。 更具体地，本发明揭示了证实蛋白质包括癌干细胞的分化，并且可以选择性地破坏癌细胞中的癌干细胞。 本发明的组合物可用于诱导已知具有癌症干细胞的各种癌症种类的分化，并且可以通过单独使用组合物或与常规抗癌剂组合来有效地抑制癌症的复发和转移; 从而可用于治疗和预防癌症疾病。
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公开(公告)号：KR1020140023738A
公开(公告)日：2014-02-27
申请号：KR1020120090104
申请日：2012-08-17
Applicant: 삼성전자주식회사 , 성균관대학교산학협력단
CPC classification number: H04W72/082
Abstract: The present invention relates to a link scheduling method of a transmission node and an interference information reporting method of a reception node in a wireless communication system which directly communicates between the transmission node and the reception node. The link scheduling method of the transmission node according to the present invention includes the steps of: receiving the interference information of one or more reception nodes by one or more transmission nodes from one or more reception nodes; performing link scheduling based on the interference information; and transmitting data according to the link scheduling result. [Reference numerals] (a) Transmission node in which there is data to be transferred: scheduling according to an interference matrix; (AA) Scheduling links in which use the interference matrix; (b) Interference matrix after calculating the scheduling; (BB) Desired signal; (CC) Interference signal; (DD) Scheduled link; (EE) Yielded link; (FF) B_INTF [nth traffic section] =; (GG) Except from a nth traffic section; (HH) Use in the nth traffic section
Abstract translation: 本发明涉及在发送节点和接收节点之间直接通信的无线通信系统中的发送节点的链路调度方法和接收节点的干扰信息报告方法。 根据本发明的传输节点的链路调度方法包括以下步骤：从一个或多个接收节点接收一个或多个传输节点的一个或多个接收节点的干扰信息; 基于干扰信息执行链路调度; 并根据链路调度结果发送数据。 （附图标记）（a）其中存在要传送的数据的传输节点：根据干扰矩阵进行调度; （AA）使用干扰矩阵的调度链路; （b）计算调度后的干扰矩阵; （BB）所需信号; （CC）干扰信号; （DD）预定链接; （EE）产生链接; （FF）B_INTF [第n个流量段] =; （GG）除第n个流量段外; （HH）在第n个流量段使用
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公开(公告)号：KR1020130142494A
公开(公告)日：2013-12-30
申请号：KR1020120065756
申请日：2012-06-19
Applicant: 삼성전자주식회사 , 성균관대학교산학협력단
IPC: H04W56/00
CPC classification number: H04W56/00 , H04W56/002
Abstract: The present invention relates to a method and a device for synchronizing a terminal in a wireless communication network. A method for synchronizing a terminal according to one implementation example of the present invention can include the following steps: an initial monitoring step for determining whether a synchronization signal is received and accordingly setting a synchronization signal reference time in an initial monitoring section of at least two frames; a transmission/reception repeating step for determining whether a synchronization signal is received and accordingly setting a synchronization signal reference time in a synchronization signal monitoring section, and transmitting a synchronization signal based on the synchronization signal reference time in a synchronization signal transmission section during a transmission/reception repeating section where synchronization signal monitoring sections and synchronization signal transmission sections are alternately placed, after the initial monitoring step; and a dedicated monitoring step for determining whether a synchronization signal is received and accordingly setting a synchronization signal reference time in a dedicated monitoring section of at least two frames, after the transmission/reception repeating step. According to one implementation example of the present invention, terminal synchronization can be implemented without the help of an infrastructure like a base station, an access point, etc. [Reference numerals] (310) Initial monitoring section;(320) N_PO frame;(330) Dedicated monitoring section;(AA) Start communications;(BB,DD) Two frames;(CC) One frame;(EE) Time
Abstract translation: 本发明涉及一种在无线通信网络中同步终端的方法和装置。 根据本发明的一个实施例的用于同步终端的方法可以包括以下步骤：初始监视步骤，用于确定是否接收到同步信号，并且相应地在初始监视部分中设置至少两个同步信号参考时间 帧; 发送/接收重复步骤，用于确定是否接收到同步信号，并且相应地在同步信号监视部分中设置同步信号参考时间，并且在发送期间在同步信号发送部分中基于同步信号参考时间发送同步信号 在初始监视步骤之后交替放置同步信号监视部分和同步信号发送部分的接收重复部分; 以及专用监视步骤，用于在发送/接收重复步骤之后，确定是否接收到同步信号，并相应地在至少两个帧的专用监视部分中设置同步信号参考时间。 （310）初始监视部分（320）N_PO帧;（320）根据本发明的一个实现示例，终端同步可以在没有诸如基站，接入点等的基础设施的帮助下实现。 330）专用监控部分;（AA）启动通信;（BB，DD）两帧;（CC）一帧;（EE）时间
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公开(公告)号：KR101142837B1
公开(公告)日：2012-05-08
申请号：KR1020100006205
申请日：2010-01-22
Applicant: 성균관대학교산학협력단
Abstract: PURPOSE: A protein shelled platinum nanoparticle complex and a manufacturing method thereof are provided to synthesize uniform nanoparticle by controlling the reaction time and the ratio of protein shell and platinum. CONSTITUTION: A protein shell is composed of hollow protein. The diameter of internal space of the protein shell is between 1.5 and 6nm. The protein of the protein shell is composed of six or more sub units. Pores are arranged between the sub units in order to connect the inner side and the outer side of the protein. The diameter of the pore is between 1 and 4nm. A protein shelled platinum nanoparticle complex is surrounded by the protein shell.
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公开(公告)号：KR100926270B1
公开(公告)日：2009-11-12
申请号：KR1020070078982
申请日：2007-08-07
Applicant: 성균관대학교산학협력단
CPC classification number: C07K14/31 , C12Q1/485 , G01N2500/04
Abstract: 본 발명은 황색 포도상구균의 TRAP 단백질의 시험관내에서의 인산화 방법에 관한 것이다. 본 발명에서는 TRAP 단백질이 자기자신을 인산화시키는 인산화 효소라는 사실을 새롭게 알아냈고, 정제된 TRAP 단백질을 인산화시키는 방법을 최초로 밝혔다. 즉, TRAP 단백질이 철, 구리 및 아연이온 존재하에서 ATP로부터 인산이온을 받아 TRAP 단백질이 인산화된다는 사실을 입증하였다. 본 발명은 시험관내에서 TRAP 단백질을 인산화시키는 방법 및 상기 방법을 이용하여 다양한 신규 화합물 및 천연물로부터 TRAP 단백질의 인산화 저해제를 효과적으로 탐색할 수 있는 방법을 제공한다. 인산화 과정은 TRAP 단백질의 기능에 필수적이기 때문에 이러한 인산화 과정을 저해하는 저해제의 개발은 포도상구균을 대상으로 한 신규 항생제 개발을 위한 기초를 제공한다. 따라서 본 발명을 이용하면 황색 포도상구균 및 이의 내성균에 대한 신규 항생제의 개발 가능성 및 속도를 획기적으로 줄일 수 있다.
TRAP 단백질, 인산화, 인산화 저해제
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