Abstract:
PURPOSE: A pharmaceutical composition containing one of rutin and Quercetin or the mixture is provided to prevent and treat hyperlipidemia, arteriosclerosis and liver diseases. CONSTITUTION: The rutin is extracted from buckwheat or leaves, stems and flowers of the buckwheat by leaving the materials at a base of pH10-12 by using calcium hydroxide, neutralizing and settling the materials, or by using 20-97% alcohol or water at a high temperature and pressure. The buckwheat and the leaves, stems and flowers also can be dried and pulverized to get powdered buckwheat. The resulting buckwheat flour or buckwheat extract containing 0.01-10wt% of the rutin, quercetin or the mixture of them is added to tomato ketchup, sauce and juice, ramen, noodle, bread, cookies and cracker, soup and gravies, ground beef, or dairy products to get functional foods.
Abstract:
본 발명은 B형 간염 바이러스 (HBV)의 표면항원 프리-S1 (pre-S1)에 결합하는 단일클론항체, 이를 생산하는 하이브리도마 세포주 및 그의 제조방법에 관한 것이다. 구체적으로, 본 발명은 HBV 표면항원 프리-S1 의 43-49번 아미노산을 포함하는 에피토프를 특이적으로 인식하는 생쥐 단일클론항체에 관한 것으로서, 이는 여러 아형 및 변이 HBV 를 중화시킬 수 있어 HBV 감염을 예방하고 치료하는데 널리 사용될 수 있다.
Abstract:
PURPOSE: A condiment composition containing garlic, onion, ginger, jujubes, powder or extracts of a tangerine pericarp is provided. It has an effect of improving health through prevention of circulatory organ-related diseases when added to food. CONSTITUTION: The condiment composition contains 1 to 30% by weight of garlic, 10 to 50% by weight of onion, 0.2 to 10% by weight of ginger, 5 to 40% by weight of jujubes, tangerines, powder or extract of a tangerine pericarp and additionally 30 to 50% by weight of oatmeal powder, based on the total weight of the composition. The tangerine pericarp extract is prepared by adding 3 to 30L 20 to 95% ethanol to 1kg tangerine pericarp, extracting for 1 to 12hr at 25 to 80deg.C and then filtering.
Abstract:
PURPOSE: A composition for increasing serum high density lipoprotein containing bioflavonoids is provided which is useful for preventing and treating diseases of cardiac circulatory organs. CONSTITUTION: The medical composition for increasing high density lipoprotein consists of(i) an effective amount of bioflavonoids of the following general formula(I) or a plant extract containing thereof, where each R¬1-R¬9 is independently hydrogen, hydroxy, alkoxy having 1-9 carbon atoms(optionally, which is able to include hydroxy, alkoxy having 1-5 carbon atoms, aryloxy or phenyl group which is substituted by one to three substituents selected from hydroxy, alkoxy, aryloxy, halogen, nitro and amido), cycloalkyloxy having 5-9 carbon atoms which is substituted by one to three substituents selected from hydroxy, alkoxy, aryloxy, halogen, nitro and amido, cycloalkylcarbonyloxy having 5-9 carbon atoms which is substituted by one to three substituents selected from hydroxy, alkoxy, aryloxy, halogen, nitro and amido, acyloxy having 2-10 or 16-18 carbon atoms(optionally, which is able to include hydroxy, alkoxy having 1-5 carbon atoms, aryloxy or phenyl group which is substituted by one to three substituents selected from hydroxy, alkoxy, aryloxy, halogen, nitro and amido), or rutinosyl, and X is either a single bond or a double bond; and (ii) a medically acceptable carrier.
Abstract:
본 발명은 대추 추출물 및 감귤류 과피 추출물을 포함하는 지질대사 개선 및 혈압강하용 조성물에 관한 것으로, 본 발명의 조성물은 의약용 및 식품용 조성물을 포함한다. 대추 추출물 및 감귤류 과피 추출물을 포함하는 본 발명의 조성물은, 동물에 투여되었을 때 간 질환, 고혈압증, 동맥경화증, 고지혈증 등의 성인병 및 암 예방 등의 효과를 나타낼 수 있다.
Abstract:
본 발명은 네오헤스페리딘 디하이드로칼콘(neohesperidin dihydrochalcone)을 포함하는 동맥경화증, 고지혈증, 간 질환, 고혈당증의 예방 및 치료용 조성물에 관한 것으로, 본 발명의 조성물은 의약용, 식품용 및 음료용 조성물을 포함한다.
Abstract:
본 발명은 네오헤스페리딘 디하이드로칼콘(neohesperidin dihydrochalcone)을 포함하는 동맥경화증, 고지혈증, 간 질환, 고혈당증의 예방 및 치료용 조성물에 관한 것으로, 본 발명의 조성물은 의약용, 식품용 및 음료용 조성물을 포함한다.
Abstract:
본 발명은 탄닌(tannin), 또는 탄닌 유래 갈산(gallic acid) 또는 엘라그산(ellagic acid)을 포함하는 동맥경화증, 고지혈증 및 간 질환의 예방 및 치료용 조성물에 관한 것으로, 탄닌, 갈산 또는 엘라그산은 동물에게 투여되었을 때 동맥내피에 대식세포-지질 복합체가 침착되는 것을 강력히 억제할 뿐만 아니라, 동물의 혈청 GOT(glutamate-oxaloacetate transaminase), GPT(glutamate-pyruvate transaminase), γGTP(γ-glutamyl transpeptidase) 및 혈중 지질의 농도를 낮추고, 간세포의 손상 및 지방간화를 강력히 억제하므로, 본 발명의 조성물은 동맥경화증, 고지혈증 및 간 질환의 예방 및 치료제로서 유용하게 사용될 수 있다.
Abstract:
PURPOSE: A food or drink composition including a bioflavonoid of formula(I) or extract of vegetables or citrus fruits containing the bioflavonoid is provided. This composition prevents hypertension, arteriosclerosis and a stroke of paralysis by increasing the plasma high density lipoprotein level in the body. CONSTITUTION: The composition for increasing plasma high density lipoprotein(HDL) level comprises a bioflavonoid of formula(I), wherein i) R1 to R9 are each independently hydrogen; hydroxy group; C1-9 alkoxy group optionally substituted with one or more substituents selected from the group consisting of hydroxy, C1-5 alkoxy, aryloxy, and phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C5-9 cycloalkyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; C5-9 cycloalkylcarbonyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; C2-10 or C16-18 acyloxy group optionally substituted with one or more substituents selected from the group consisting of a hydroxy, C1-5 alkoxy, aryloxy, and phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen and nitro group; rutinosyl group; or rhaminosyl group, and ii) X is a single or double bond. The bioflavonoid of formula(I) or extract of vegetables or citrus fruits containing the bioflavonoid can be added to various foods or drinks.